LOCUS X16150 2330 bp mRNA linear HUM 22-MAR-1995
DEFINITION Human Lyam-1 mRNA for leukocyte adhesion molecule-1.
ACCESSION X16150
VERSION X16150.1
KEYWORDS cell surface protein; leukocyte adhesion protein; transmembrane
protein.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2330)
AUTHORS Tedder T.F.
JOURNAL Submitted (09-NOV-1989) to the INSDC. Tedder T.F.
REFERENCE 2 (bases 1 to 2330)
AUTHORS Tedder T.F., Isaacs C.M., Ernst T.J., Demetri G.D., Adler D.A.,
Disteche C.M.
TITLE Isolation and chromosomal localization of cDNAs encoding a novel
human lymphocyte cell surface molecule, LAM-1
JOURNAL J. Exp. Med. 170(1), 123-133(1989).
PUBMED 2473156
FEATURES Location/Qualifiers
source 1..2330
/db_xref="H-InvDB:HIT000321540"
/organism="Homo sapiens"
/chromosome="1q23-25"
/mol_type="mRNA"
/clone_lib="lambda gt11"
/clone="pLAM-1"
/tissue_type="tonsil"
/db_xref="taxon:9606"
CDS 92..1210
/note="prepro-polypeptide (AA -28 to 344)"
/db_xref="GOA:P14151"
/db_xref="H-InvDB:HIT000321540.14"
/db_xref="HGNC:HGNC:10720"
/db_xref="InterPro:IPR000436"
/db_xref="InterPro:IPR000742"
/db_xref="InterPro:IPR001304"
/db_xref="InterPro:IPR002396"
/db_xref="InterPro:IPR013032"
/db_xref="InterPro:IPR016186"
/db_xref="InterPro:IPR016187"
/db_xref="InterPro:IPR016348"
/db_xref="InterPro:IPR018378"
/db_xref="InterPro:IPR033991"
/db_xref="InterPro:IPR035976"
/db_xref="PDB:1KJB"
/db_xref="PDB:2LGF"
/db_xref="PDB:3CFW"
/db_xref="PDB:5VC1"
/db_xref="UniProtKB/Swiss-Prot:P14151"
/protein_id="CAA34275.1"
/translation="MIFPWKCQSTQRDLWNIFKLWGWTMLCCDFLAHHGTDCWTYHYS
EKPMNWQRARRFCRDNYTDLVAIQNKAEIEYLEKTLPFSRSYYWIGIRKIGGIWTWVG
TNKSLTEEAENWGDGEPNNKKNKEDCVEIYIKRNKDAGKWNDDACHKLKAALCYTASC
QPWSCSGHGECVEIINNYTCNCDVGYYGPQCQFVIQCEPLEAPELGTMDCTHPLGNFN
FNSQCAFSCSEGTNLTGIEETTCEPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHPL
ASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPSPICQKLDKSFSMIKEGDYNPL
FIPVAVMVTAFSGLAFIIWLARRLKKGKKSKRSMNDPY"
sig_peptide 92..175
/note="signal peptide (AA -28 to -1)"
misc_feature 176..1207
/note="propeptide (AA 1 to 344)"
mat_peptide 206..1207
/note="mature leukocyte adhesion protein (AA 11 to 344)"
misc_feature 2296..2301
/note="polyA attachment site"
BASE COUNT 661 a 522 c 487 g 660 t
ORIGIN
1 gaattccctt tgggcaagga cctgagaccc ttgtgctaag tcaagaggct caatgggctg
61 cagaagaact agagaaggac caagcaaagc catgatattt ccatggaaat gtcagagcac
121 ccagagggac ttatggaaca tcttcaagtt gtgggggtgg acaatgctct gttgtgattt
181 cctggcacat catggaaccg actgctggac ttaccattat tctgaaaaac ccatgaactg
241 gcaaagggct agaagattct gccgagacaa ttacacagat ttagttgcca tacaaaacaa
301 ggcggaaatt gagtatctgg agaagactct gcctttcagt cgttcttact actggatagg
361 aatccggaag ataggaggaa tatggacgtg ggtgggaacc aacaaatctc tcactgaaga
421 agcagagaac tggggagatg gtgagcccaa caacaagaag aacaaggagg actgcgtgga
481 gatctatatc aagagaaaca aagatgcagg caaatggaac gatgacgcct gccacaaact
541 aaaggcagcc ctctgttaca cagcttcttg ccagccctgg tcatgcagtg gccatggaga
601 atgtgtagaa atcatcaata attacacctg caactgtgat gtggggtact atgggcccca
661 gtgtcagttt gtgattcagt gtgagccttt ggaggcccca gagctgggta ccatggactg
721 tactcaccct ttgggaaact tcaacttcaa ctcacagtgt gccttcagct gctctgaagg
781 aacaaactta actgggattg aagaaaccac ctgtgaacca tttggaaact ggtcatctcc
841 agaaccaacc tgtcaagtga ttcagtgtga gcctctatca gcaccagatt tggggatcat
901 gaactgtagc catcccctgg ccagcttcag ctttacctct gcatgtacct tcatctgctc
961 agaaggaact gagttaattg ggaagaagaa aaccatttgt gaatcatctg gaatctggtc
1021 aaatcctagt ccaatatgtc aaaaattgga caaaagtttc tcaatgatta aggagggtga
1081 ttataacccc ctcttcattc cagtggcagt catggttact gcattctctg ggttggcatt
1141 tatcatttgg ctggcaagga gattaaaaaa aggcaagaaa tccaagagaa gtatgaatga
1201 cccatattaa atcgcccttg gtgaaagaaa attcttggaa tactaaaaat catgagatcc
1261 tttaaatcct tccatgaaac gttttgtgtg gtggcacctc ctacgtcaaa catgaagtgt
1321 gtttccttca gtgcatctgg gaagatttct acctgaccaa cagttccttc agcttccatt
1381 tcacccctca tttatccctc aacccccagc ccacaggtgt ttatacagct cagctttttg
1441 tcttttctga ggagaaacaa ataagaccat aaagggaaag gattcatgtg gaatataaag
1501 atggctgact ttgctctttc ttgactcttg ttttcagttt caattcagtg ctgtacttga
1561 tgacagacac ttctaaatga agtgcaaatt tgatacatat gtgaatatgg actcagtttt
1621 cttgcagatc aaatttcgcg tcgtcttctg tatacgtgga ggtacactct atgaagtcaa
1681 aagtctacgc tctcctttct ttctaactcc agtgaagtaa tggggtcctg ctcaagttga
1741 aagagtccta tttgcactgt agcctcgccg tctgtgaatt ggaccatcct atttaactgg
1801 cttcagcctc cccaccttct tcagccacct ctctttttca gttggctgac ttccacacct
1861 agcatctcat gagtgccaag caaaaggaga gaagagagaa atagcctgcg ctgtttttta
1921 gtttgggggt tttgctgttt ccttttatga gacccattcc tatttcttat agtcaatgtt
1981 tcttttatca cgatattatt agtaagaaaa catcactgaa atgctagctg caactgacat
2041 ctctttgatg tcatatggaa gagttaaaac aggtggagaa attccttgat tcacaatgaa
2101 atgctctcct ttcccctgcc cccagacctt ttatccactt acctagattc tacatattct
2161 ttaaatttca tctcaggcct ccctcaaccc caccacttct tttataacta gtcctttact
2221 aatccaaccc atgatgagct cctcttcctg gcttcttact gaaaggttac cctgtaacat
2281 gcaattttgc atttgaataa agcctgcttt ttaagtgtta aaaagaattc
//