LOCUS X14390 1924 bp mRNA linear HUM 18-APR-2005
DEFINITION Human mRNA for lipoprotein lipase (EC 3.1.1.34).
ACCESSION X14390
VERSION X14390.1
KEYWORDS lipoprotein lipase.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1924)
AUTHORS Senda M.
JOURNAL Submitted (15-FEB-1989) to the INSDC. Senda M., Department of
Molecular Genetics, Nippon Roche Research Center, 200 Kaziwara
Kamakura shi, Kanagawa 247, Japan.
REFERENCE 2 (bases 1 to 1924)
AUTHORS Gotoda T., Senda M., Gamou T., Furuichi Y., Oka K.
TITLE Nucleotide sequence of human cDNA coding for a lipoprotein lipase
(LPL) cloned from placental cDNA library
JOURNAL Nucleic Acids Res. 17(6), 2351-2351(1989).
PUBMED 2701938
COMMENT The sequence overlaps with that reported by Wion et. al. in
Science 235:1638-1641(1987).
FEATURES Location/Qualifiers
source 1..1924
/db_xref="H-InvDB:HIT000321424"
/organism="Homo sapiens"
/map="chromosome 8p22"
/mol_type="mRNA"
/clone_lib="placenta cDNA"
/tissue_type="placenta"
/db_xref="taxon:9606"
CDS 118..1545
/note="lipase precurser (AA -27 to 448)"
/db_xref="GOA:P06858"
/db_xref="H-InvDB:HIT000321424.13"
/db_xref="HGNC:HGNC:6677"
/db_xref="InterPro:IPR000734"
/db_xref="InterPro:IPR001024"
/db_xref="InterPro:IPR002330"
/db_xref="InterPro:IPR013818"
/db_xref="InterPro:IPR016272"
/db_xref="InterPro:IPR029058"
/db_xref="InterPro:IPR033906"
/db_xref="InterPro:IPR036392"
/db_xref="PDB:6E7K"
/db_xref="PDB:6OAU"
/db_xref="PDB:6OAZ"
/db_xref="PDB:6OB0"
/db_xref="UniProtKB/Swiss-Prot:P06858"
/protein_id="CAA32564.1"
/translation="MESKALLVLTLAVWLQSLTASRGGVAAADQRRDFIDIESKFALR
TPEDTAEDTCHLIPGVAESVATCHFNHSSKTFMVIHGWTVTGMYESWVPKLVAALYKR
EPDSNVIVVDWLSRAQEHYPVSAGYTKLVGQDVARFINWMEEEFNYPLDNVHLLGYSL
GAHAAGIAGSLTNKKVNRITGLDPAGPNFEYAEAPSRLSPDDADFVDVLHTFTRGSPG
RSIGIQKPVGHVDIYPNGGTFQPGCNIGEAIRVIAERGLGDVDQLVKCSHERSIHLFI
DSLLNEENPSKAYRCSSKEAFEKGLCLSCRKNRCNNLGYEINKVRAKRSSKMYLKTRS
QMPYKVFHYQVKIHFSGTESETHTNQAFEISLYGTVAESENIPFTLPEVSTNKTYSFL
IYTEVDIGELLMLKLKWKSDSYFSWSDWWSSPGFAIQKIRVKAGETQKKVIFCSREKV
SHLQKGKAPAVFVKCHDKSLNKKSG"
sig_peptide 118..198
/note="signal peptide (AA -27 to -1)"
mat_peptide 199..1542
/note="mature lipase (AA 1-448)"
BASE COUNT 532 a 445 c 488 g 459 t
ORIGIN
1 gggcgggggc gacttgctca gcgccaaacc gcggctccag ccctctccag cctccggctc
61 agccggctca tcagtcggtc cgcgccttgc agctcctcca gagggacgcg ccccgagatg
121 gagagcaaag ccctgctcgt gctgactctg gccgtgtggc tccagagtct gaccgcctcc
181 cgcggagggg tggccgccgc cgaccaaaga agagatttta tcgacatcga aagtaaattt
241 gccctaagga cccctgaaga cacagctgag gacacttgcc acctcattcc cggagtagca
301 gagtccgtgg ctacctgtca tttcaatcac agcagcaaaa ccttcatggt gatccatggc
361 tggacggtaa caggaatgta tgagagttgg gtgccaaaac ttgtggccgc cctgtacaag
421 agagaaccag actccaatgt cattgtggtg gactggctgt cacgggctca ggagcattac
481 ccagtgtccg cgggctacac caaactggtg ggacaggatg tggcccggtt tatcaactgg
541 atggaggagg agtttaacta ccctctggac aatgtccatc tcttgggata cagccttgga
601 gcccatgctg ctggcattgc aggaagtctg accaataaga aagtcaacag aattactggc
661 ctcgatccag ctggacctaa ctttgagtat gcagaagccc cgagtcgtct ttctcctgat
721 gatgcagatt ttgtagacgt cttacacaca ttcaccagag ggtcccctgg tcgaagcatt
781 ggaatccaga aaccagttgg gcatgttgac atttacccga atggaggtac ttttcagcca
841 ggatgtaaca ttggagaagc tatccgcgtg attgcagaga gaggacttgg agatgtggac
901 cagctagtga agtgctccca cgagcgctcc attcatctct tcatcgactc tctgttgaat
961 gaagaaaatc caagtaaggc ctacaggtgc agttccaagg aagcctttga gaaagggctc
1021 tgcttgagtt gtagaaagaa ccgctgcaac aatctgggct atgagatcaa taaagtcaga
1081 gccaaaagaa gcagcaaaat gtacctgaag actcgttctc agatgcccta caaagtcttc
1141 cattaccaag taaagattca tttttctggg actgagagtg aaacccatac caatcaggcc
1201 tttgagattt ctctgtatgg caccgtggcc gagagtgaga acatcccatt cactctgcct
1261 gaagtttcca caaataagac ctactccttc ctaatttaca cagaggtaga tattggagaa
1321 ctactcatgt tgaagctcaa atggaagagt gattcatact ttagctggtc agactggtgg
1381 agcagtcccg gcttcgccat tcagaagatc agagtaaaag caggagagac tcagaaaaag
1441 gtgatcttct gttctaggga gaaagtgtct catttgcaga aaggaaaggc acctgcggta
1501 tttgtgaaat gccatgacaa gtctctgaat aagaagtcag gctgaaactg ggcgaatcta
1561 cagaacaaag aacggcatgt gaattctgtg aagaatgaag tggaggaagt aacttttaca
1621 aaacataccc agtgtttggg gtgtttcaaa agtggatttt cctgaatatt aatcccagcc
1681 ctacccttgt tagttatttt aggagacagt ctcaagcact aaaaagtggc taattcaatt
1741 tatggggtat agtggccaaa tagcacatcc tccaacgtta aaagacagtg gatcatgaaa
1801 agtgctgttt tgtcctttga gaaagaaata attgtttgag cgcagagtaa aataaggctc
1861 cttcatgtgg cgtattgggc catagcctat aattggttag aacctcctat tttaattgga
1921 attc
//