LOCUS X14253 2033 bp mRNA linear HUM 07-OCT-2008
DEFINITION Human mRNA for cripto protein.
ACCESSION X14253
VERSION X14253.1
KEYWORDS Alu repetitive sequence; CRIPTO protein; EGF-like sequence.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2033)
AUTHORS Persico M.
JOURNAL Submitted (26-MAY-1989) to the INSDC. Persico M., International
Institute of Genetics and Biophysics, CNR, Via Marconi, 10, 80125
Naples, Italy.
REFERENCE 2
AUTHORS Ciccodicola A., Dono R., Obici S., Simeone A., Zollo M.,
Persico M.G.
TITLE Molecular characterization of a gene of the 'EGF family' expressed
in undifferentiated human NTERA2 teratocarcinoma cells
JOURNAL EMBO J. 8(7), 1987-1991(1989).
PUBMED 2792079
COMMENT Data kindly reviewed (18-JUL-1990) by Persico M.G.
FEATURES Location/Qualifiers
source 1..2033
/db_xref="H-InvDB:HIT000321414"
/organism="Homo sapiens"
/mol_type="mRNA"
/cell_line="NTERA2/D1"
/cell_type="teratocarcinoma"
/db_xref="taxon:9606"
CDS 248..814
/note="cripto protein (AA 1-188)"
/db_xref="GOA:P13385"
/db_xref="H-InvDB:HIT000321414.14"
/db_xref="HGNC:HGNC:11701"
/db_xref="InterPro:IPR000742"
/db_xref="InterPro:IPR013032"
/db_xref="InterPro:IPR017047"
/db_xref="InterPro:IPR019011"
/db_xref="UniProtKB/Swiss-Prot:P13385"
/protein_id="CAA32467.1"
/translation="MDCRKMARFSYSVIWIMAISKVFELGLVAGLGHQEFARPSRGYL
AFRDDSIWPQEEPAIRPRSSQRVPPMGIQHSKELNRTCCLNGGTCMLGSFCACPPSFY
GRNCEHDVRKENCGSVPHDTWLPKKCSLCKCWHGQLRCFPQAFLPGCDGLVMDEHLVA
SRTPELPPSARTTTFMLVGICLSIQSYY"
repeat_region 1080..1370
/note="Alu repetitive sequence"
misc_feature 1995..2000
/note="polyA signal"
BASE COUNT 562 a 447 c 430 g 594 t
ORIGIN
1 ggagaatccc cggaaaggct gagtctccag ctcaaggtca aaacgtccaa ggccgaaagc
61 cctccagttt cccctggacg ccttgctcct gcttctgcta cgaccttctg gggaaaacga
121 atttctcatt ttcttcttaa attgccattt tcgctttagg agatgaatgt tttcctttgg
181 ctgttttggc aatgactctg aattaaagcg atgctaacgc ctcttttccc cctaattgtt
241 aaaagctatg gactgcagga agatggcccg cttctcttac agtgtgattt ggatcatggc
301 catttctaaa gtctttgaac tgggattagt tgccgggctg ggccatcagg aatttgctcg
361 tccatctcgg ggatacctgg ccttcagaga tgacagcatt tggccccagg aggagcctgc
421 aattcggcct cggtcttccc agcgtgtgcc gcccatgggg atacagcaca gtaaggagct
481 aaacagaacc tgctgcctga atgggggaac ctgcatgctg gggtcctttt gtgcctgccc
541 tccctccttc tacggacgga actgtgagca cgatgtgcgc aaagagaact gtgggtctgt
601 gccccatgac acctggctgc ccaagaagtg ttccctgtgt aaatgctggc acggtcagct
661 ccgctgcttt cctcaggcat ttctacccgg ctgtgatggc cttgtgatgg atgagcacct
721 cgtggcttcc aggactccag aactaccacc gtctgcacgt actaccactt ttatgctagt
781 tggcatctgc ctttctatac aaagctacta ttaatcgaca ttgacctatt tccagaaata
841 caattttaga tatcatgcaa atttcatgac cagtaaaggc tgctgctaca atgtcctaac
901 tgaaagatga tcatttgtag ttgccttaaa ataatgaata caatttccaa aatggtctct
961 aacatttcct tacagaacta cttcttactt ctttgccctg ccctctccca aaaaactact
1021 tcttttttca aaagaaagtc agccatatct ccattgtgcc taagtccagt gtttcttttt
1081 tttttttttt ttgagacgga gtctcactct gtcacccagg ctggactgca atgacgcgat
1141 cttggttcac tgcaacctcc gcatccgggg ttcaagccat tctcctgcct aagcctccca
1201 agtaactggg attacaggca tgtgtcacca tgcccagcta atttttttgt attttagtag
1261 agatgggggt ttcaccatat tggccagtct ggtctcgaac tctgaccttg tgatccatcg
1321 atcagcctct cgagtgctga gattacacac gtgagcaact gtgcaaggcc tggtgtttct
1381 tgatacatgt aattctacca aggtcttctt aatatgttct tttaaatgat tgaattatat
1441 gttcagatta ttggagacta attctaatgt ggaccttaga atacagtttt gagtagagtt
1501 gatcaaaatc aattaaaata gtctctttaa aaggaaagaa aacatcttta aggggaggaa
1561 ccagagtgct gaaggaatgg aagtccatct gcgtgtgtgc agggagactg ggtaggaaag
1621 aggaagcaaa tagaagagag aggttgaaaa acaaaatggg ttacttgatt ggtgattagg
1681 tggtggtaga gaagcaagta aaaaggctaa atggaagggc aagtttccat catctataga
1741 aagctatata agacaagaac tccccttttt ttcccaaagg cattataaaa agaatgaagc
1801 ctccttagaa aaaaaattat acctcaatgt ccccaacaag attgcttaat aaattgtgtt
1861 tcctccaagc tattcaattc ttttaactgt tgtagaagac aaaatgttca caatatattt
1921 agttgtaaac caagtgatca aactacatat tgtaaagccc atttttaaaa tacattgtat
1981 atatgtgtat gcacagtaaa aatggaaact atattgacct aaaaaaaaaa aaa
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