LOCUS X13973 1921 bp mRNA linear HUM 12-SEP-1993
DEFINITION Human mRNA for ribonuclease/angiogenin inhibitor (RAI).
ACCESSION X13973
VERSION X13973.1
KEYWORDS angiogenin inhibitor; glycoprotein; ribonuclease inhibitor.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1921)
AUTHORS Schneider R., Schneider-Scherzer E., Thurnher M., Auer B.,
Schweiger M.
TITLE The primary structure of human ribonuclease/angiogenin inhibitor
(RAI) discloses a novel highly diversified protein superfamily with
a common repetitive module
JOURNAL EMBO J. 7(13), 4151-4156(1988).
PUBMED 3243277
FEATURES Location/Qualifiers
source 1..1921
/db_xref="H-InvDB:HIT000321406"
/organism="Homo sapiens"
/mol_type="mRNA"
/clone_lib="lambda gt11"
/clone="OBR2.1"
/cell_line="HeLa"
/db_xref="taxon:9606"
CDS 361..1746
/note="ribonuclease/angiogenin inhibitor (AA 1-461)"
/db_xref="GOA:P13489"
/db_xref="H-InvDB:HIT000321406.12"
/db_xref="HGNC:HGNC:10074"
/db_xref="InterPro:IPR001611"
/db_xref="InterPro:IPR006553"
/db_xref="InterPro:IPR032675"
/db_xref="InterPro:IPR041302"
/db_xref="PDB:1A4Y"
/db_xref="PDB:1Z7X"
/db_xref="PDB:2BEX"
/db_xref="PDB:2Q4G"
/db_xref="UniProtKB/Swiss-Prot:P13489"
/protein_id="CAA32151.1"
/translation="MSLDIQSLDIQCEELSDARWAELLPLLQQCQVVRLDDCGLTEAR
CKDISSALRVNPALAELNLRSNELGDVGVHCVLQGLQTPSCKIQKLSLQNCCLTGAGC
GVLSSTLRTLPTLQELHLSDNLLGDAGLQLLCEGLLDPQCRLEKLQLEYCSLSAASCE
PLASVLRAKPDFKELTVSNNDINEAGVRVLCQGLKDSPCQLEALKLESCGVTSDNCRD
LCGIVASKASLRELALGSNKLGDVGMAELCPGLLHPSSRLRTLWIWECGITAKGCGDL
CRVLRAKESLKELSLAGNELGDEGARLLCETLLEPGCQLESLWVKSCSFTAACCSHFS
SVLAQNRFLLELQISNNRLEDAGVRELCQGLGQPGSVLRVLWLADCDVSDSSCSSLAA
TLLANHSLRELDLSNNCLGDAGILQLVESVSEPGCLLEQLVLYDIYWSEEMEDRLQAL
EKDKPSLRVIS"
misc_feature 1903..1908
/note="pot.polyA signal"
polyA_site 1921..1921
/note="polyA site"
BASE COUNT 369 a 605 c 591 g 356 t
ORIGIN
1 agtgccttag attccagcga gctacgaagc aatcctggcc cagccgagct tgcttcccca
61 aatcccgtaa tccttgacct tattccccca aagaagcggc ctcccgggaa ggagcgccct
121 ggcggagaag actcgaacgg ctcccacagc cgggcgttgg gggtaaaggc atgaagaact
181 cttgactgac agaaacggag ggtgtgtcca aagttttgag gacggccgag cggcgctcca
241 aaacccgtcc tcacagcctc gccccgttcg cctcagctac aacaaatcat cgtcaacctg
301 ttccaccttc tccagtctgg tagcaaaaag gggtgtctca ggccactctt cacctccacc
361 atgagcctgg acatccagag cctggacatc cagtgtgagg agctgagcga cgctagatgg
421 gccgagctcc tccctctgct ccagcagtgc caagtggtca ggctggacga ctgtggcctc
481 acggaagcac ggtgcaagga catcagctct gcacttcgag tcaaccctgc actggcagag
541 ctcaacctgc gcagcaacga gctgggcgat gtcggcgtgc attgcgtgct ccagggcctg
601 cagaccccct cctgcaagat ccagaagctg agcctccaga actgctgcct gacgggggcc
661 ggctgcgggg tcctgtccag cacactacgc accctgccca ccctgcagga gctgcacctc
721 agcgacaacc tcttggggga tgcgggcctg cagctgctct gcgaaggact cctggacccc
781 cagtgccgcc tggaaaagct gcagctggag tattgcagcc tctcggctgc cagctgcgag
841 cccctggcct ccgtgctcag ggccaagccg gacttcaagg agctcacggt tagcaacaac
901 gacatcaatg aggctggcgt ccgtgtgctg tgccagggcc tgaaggactc cccctgccag
961 ctggaggcgc tcaagctgga gagctgcggt gtgacatcag acaactgccg ggacctgtgc
1021 ggcattgtgg cctccaaggc ctcgctgcgg gagctggccc tgggcagcaa caagctgggt
1081 gatgtgggca tggcggagct gtgcccaggg ctgctccacc ccagctccag gctcaggacc
1141 ctgtggatct gggagtgtgg catcactgcc aagggctgcg gggatctgtg ccgtgtcctc
1201 agggccaagg agagcctgaa ggagctcagc ctggccggca acgagctggg ggatgagggt
1261 gcccgactgc tgtgtgagac cctgctggaa cctggctgcc agctggagtc gctgtgggtg
1321 aagtcctgca gcttcacagc cgcctgctgc tcccacttca gctcagtgct ggcccagaac
1381 aggtttctcc tggagctaca gataagcaac aacaggctgg aggatgcggg cgtgcgggag
1441 ctgtgccagg gcctgggcca gcctggctct gtgctgcggg tgctctggtt ggccgactgc
1501 gatgtgagtg acagcagctg cagcagcctc gccgcaaccc tgttggccaa ccacagcctg
1561 cgtgagctgg acctcagcaa caactgcctg ggggacgcgg gcatcctgca gctggtggag
1621 agcgtatccg agccgggctg cctcctggag cagctggtcc tgtacgacat ttactggtct
1681 gaggagatgg aggaccggct gcaggccctg gagaaggaca agccatccct gagggtcatc
1741 tcctgaagct cttcctgctg ctgctctccc tggacgaccg gcctcgaggc aaccctgggg
1801 cccaccagcc cctgccatgc tctcaccctg catatcctag gtttgaagag aaacgctcag
1861 atccgcttat ttctgccagt atattttgga cactttataa tcattaaagc actttcttgg
1921 c
//