LOCUS X12530 1474 bp mRNA linear HUM 12-SEP-1993
DEFINITION Human mRNA for B lymphocyte antigen CD20 (B1, Bp35).
ACCESSION X12530
VERSION X12530.1
KEYWORDS antigen; CD20 antigen; glycoprotein; integral membrane protein.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1474)
AUTHORS Stamencovic I., Seed B.
TITLE Analysis of two cDNA clones encoding the B lymphocyte antigen CD20
(B1, Bp35), a type III integral membrane protein.
JOURNAL J. Exp. Med. 167(6), 1975-1980(1988).
PUBMED 3260267
FEATURES Location/Qualifiers
source 1..1474
/db_xref="H-InvDB:HIT000321311"
/organism="Homo sapiens"
/mol_type="mRNA"
/clone="CD20.4."
/cell_line="Daudi"
/db_xref="taxon:9606"
mRNA <1..>1474
/note="CD20.4 mRNA"
mRNA <1..1041
/note="CD20.6 mRNA"
CDS 94..987
/note="CD20 antigen (AA 1 - 297)"
/db_xref="GOA:P11836"
/db_xref="H-InvDB:HIT000321311.12"
/db_xref="HGNC:HGNC:7315"
/db_xref="InterPro:IPR007237"
/db_xref="InterPro:IPR030417"
/db_xref="InterPro:IPR030418"
/db_xref="PDB:1S8B"
/db_xref="PDB:2OSL"
/db_xref="PDB:3BKY"
/db_xref="PDB:3PP4"
/db_xref="UniProtKB/Swiss-Prot:P11836"
/protein_id="CAA31046.1"
/translation="MTTPRNSVNGTFPAEPMKGPIAMQSGPKPLFRRMSSLVGPTQSF
FMRESKTLGAVQIMNGLFHIALGGLLMIPAGIYAPICVTVWYPLWGGIMYIISGSLLA
ATEKNSRKCLVKGKMIMNSLSLFAAISGMILSIMDILNIKISHFLKMESLNFIRAHTP
YINIYNCEPANPSEKNSPSTQYCYSIQSLFLGILSVMLIFAFFQELVIAGIVENEWKR
TCSRPKSNIVLLSAEEKKEQTIEIKEEVVGLTETSSQPKNEEDIEIIPIQEEEEEETE
TNFPEPPQDQESSPIENDSSP"
misc_feature 118..126
/note="pot. N-linked glycosylation site"
misc_feature 970..978
/note="pot. N-linked glycosylation site"
polyA_site 1041..1041
/note="polyA site CD20.6"
BASE COUNT 434 a 322 c 286 g 432 t
ORIGIN
1 aaagacaaac tgcacccact gaactccgca gctagcatcc aaatcagccc ttgagatttg
61 aggccttgga gactcaggag ttttgagagc aaaatgacaa cacccagaaa ttcagtaaat
121 gggactttcc cggcagagcc aatgaaaggc cctattgcta tgcaatctgg tccaaaacca
181 ctcttcagga ggatgtcttc actggtgggc cccacgcaaa gcttcttcat gagggaatct
241 aagactttgg gggctgtcca gattatgaat gggctcttcc acattgccct ggggggtctt
301 ctgatgatcc cagcagggat ctatgcaccc atctgtgtga ctgtgtggta ccctctctgg
361 ggaggcatta tgtatattat ttccggatca ctcctggcag caacggagaa aaactccagg
421 aagtgtttgg tcaaaggaaa aatgataatg aattcattga gcctctttgc tgccatttct
481 ggaatgattc tttcaatcat ggacatactt aatattaaaa tttcccattt tttaaaaatg
541 gagagtctga attttattag agctcacaca ccatatatta acatatacaa ctgtgaacca
601 gctaatccct ctgagaaaaa ctccccatct acccaatact gttacagcat acaatctctg
661 ttcttgggca ttttgtcagt gatgctgatc tttgccttct tccaggaact tgtaatagct
721 ggcatcgttg agaatgaatg gaaaagaacg tgctccagac ccaaatctaa catagttctc
781 ctgtcagcag aagaaaaaaa agaacagact attgaaataa aagaagaagt ggttgggcta
841 actgaaacat cttcccaacc aaagaatgaa gaagacattg aaattattcc aatccaagaa
901 gaggaagaag aagaaacaga gacgaacttt ccagaacctc cccaagatca ggaatcctca
961 ccaatagaaa atgacagctc tccttaagtg atttcttctg ttttctgttt ccttttttaa
1021 acattagtgt tcatagcttc caagagacat gctgactttc atttcttgag gtactctgca
1081 catacgcacc acatctctat ctggcctttg catggagtga ccatagctcc ttctctctta
1141 cattgaatgt agagaatgta gccattgtag cagcttgtgt tgtcacgctt cttcttttga
1201 gcaactttct tacactgaag aaaggcagaa tgagtgcttc agaatgtgat ttcctactaa
1261 cctgttcctt ggataggctt tttagtatag tatttttttt tgtcattttc tccatcagca
1321 accagggaga ctgcacctga tggaaaagat atatgactgc ttcatgacat tcctaaacta
1381 tctttttttt attccacatc tacgtttttg gtggagtccc tttttatcat ccttaaaaca
1441 atgatgcaaa agggctttag agcacaatgg atct
//