LOCUS X07384 3600 bp mRNA linear HUM 12-SEP-1993
DEFINITION Human mRNA for GLI protein.
ACCESSION X07384
VERSION X07384.1
KEYWORDS GLI protein; zinc finger protein.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3600)
AUTHORS Kinzler K.W.
JOURNAL Submitted (03-MAY-1988) to the INSDC.
REFERENCE 2 (bases 1 to 3600)
AUTHORS Kinzler K.W., Ruppert J.M., Bigner S.H., Vogelstein B.
TITLE The GLI gene is a member of the Kruppel family of zinc finger
proteins
JOURNAL Nature 332(6162), 371-374(1988).
PUBMED 2832761
FEATURES Location/Qualifiers
source 1..3600
/db_xref="H-InvDB:HIT000321255"
/organism="Homo sapiens"
/mol_type="mRNA"
/clone_lib="lambda phage clones M5E, H31, I2G, J36"
/cell_line="D-259 MG"
/db_xref="taxon:9606"
CDS 79..3399
/note="GLI protein (AA 1-1106)"
/db_xref="GOA:P08151"
/db_xref="H-InvDB:HIT000321255.14"
/db_xref="HGNC:HGNC:4317"
/db_xref="InterPro:IPR013087"
/db_xref="InterPro:IPR032850"
/db_xref="InterPro:IPR036236"
/db_xref="PDB:2GLI"
/db_xref="PDB:4BLB"
/db_xref="PDB:4KMD"
/db_xref="PDB:5OM0"
/db_xref="UniProtKB/Swiss-Prot:P08151"
/protein_id="CAA30297.1"
/translation="MFNSMTPPPISSYGEPCCLRPLPSQGAPSVGTEGLSGPPFCHQA
NLMSGPHSYGPARETNSCTEGPLFSSPRSAVKLTKKRALSISPLSDASLDLQTVIRTS
PSSLVAFINSRCTSPGGSYGHLSIGTMSPSLGFPAQMNHQKGPSPSFGVQPCGPHDSA
RGGMIPHPQSRGPFPTCQLKSELDMLVGKCREEPLEGDMSSPNSTGIQDPLLGMLDGR
EDLEREEKREPESVYETDCRWDGCSQEFDSQEQLVHHINSEHIHGERKEFVCHWGGCS
RELRPFKAQYMLVVHMRRHTGEKPHKCTFEGCRKSYSRLENLKTHLRSHTGEKPYMCE
HEGCSKAFSNASDRAKHQNRTHSNEKPYVCKLPGCTKRYTDPSSLRKHVKTVHGPDAH
VTKRHRGDGPLPRAPSISTVEPKREREGGPIREESRLTVPEGAMKPQPSPGAQSSCSS
DHSPAGSAANTDSGVEMTGNAGGSTEDLSSLDEGPCIAGTGLSTLRRLENLRLDQLHQ
LRPIGTRGLKLPSLSHTGTTVSRRVGPPVSLERRSSSSSSISSAYTVSRRSSLASPFP
PGSPPENGASSLPGLMPAQHYLLRARYASARGGGTSPTAASSLDRIGGLPMPPWRSRA
EYPGYNPNAGVTRRASDPAQAADRPAPARVQRFKSLGCVHTPPTVAGGGQNFDPYLPT
SVYSPQPPSITENAAMDARGLQEEPEVGTSMVGSGLNPYMDFPPTDTLGYGGPEGAAA
EPYGARGPGSLPLGPGPPTNYGPNPCPQQASYPDPTQETWGEFPSHSGLYPGPKALGG
TYSQCPRLEHYGQVQVKPEQGCPVGSDSTGLAPCLNAHPSEGPPHPQPLFSHYPQPSP
PQYLQSGPYTQPPPDYLPSEPRPCLDFDSPTHSTGQLKAQLVCNYVQSQQELLWEGGG
REDAPAQEPSYQSPKFLGGSQVSPSRAKAPVNTYGPGFGPNLPNHKSGSYPTPSPCHE
NFVVGANRASHRAAAPPRLLPPLPTCYGPLKVGGTNPSCGHPEVGRLGGGPALYPPPE
GQVCNPLDSLDLDNTQLDFVAILDEPQGLSPPPSHDQRGSSGHTPPPSGPPNMAVGNM
SVLLRSLPGETEFLNSSA"
misc_feature 781..1250
/note="zinc finger region (AA 235-393)"
BASE COUNT 785 a 1161 c 949 g 705 t
ORIGIN
1 cccagactcc agccctggac cgcgcatccc gagcccagcg cccagacaga gtgtccccac
61 accctcctct gagacgccat gttcaactcg atgaccccac caccaatcag tagctatggc
121 gagccctgct gtctccggcc cctccccagt cagggggccc ccagtgtggg gacagaagga
181 ctgtctggcc cgcccttctg ccaccaagct aacctcatgt ccggccccca cagttatggg
241 ccagccagag agaccaacag ctgcaccgag ggcccactct tttcttctcc ccggagtgca
301 gtcaagttga ccaagaagcg ggcactgtcc atctcacctc tgtcggatgc cagcctggac
361 ctgcagacgg ttatccgcac ctcacccagc tccctcgtag ctttcatcaa ctcgcgatgc
421 acatctccag gaggctccta cggtcatctc tccattggca ccatgagccc atctctggga
481 ttcccagccc agatgaatca ccaaaaaggg ccctcgcctt cctttggggt ccagccttgt
541 ggtccccatg actctgcccg gggtgggatg atcccacatc ctcagtcccg gggacccttc
601 ccaacttgcc agctgaagtc tgagctggac atgctggttg gcaagtgccg ggaggaaccc
661 ttggaaggtg atatgtccag ccccaactcc acaggcatac aggatcccct gttggggatg
721 ctggatgggc gggaggacct cgagagagag gagaagcgtg agcctgaatc tgtgtatgaa
781 actgactgcc gttgggatgg ctgcagccag gaatttgact cccaagagca gctggtgcac
841 cacatcaaca gcgagcacat ccacggggag cggaaggagt tcgtgtgcca ctgggggggc
901 tgctccaggg agctgaggcc cttcaaagcc cagtacatgc tggtggttca catgcgcaga
961 cacactggcg agaagccaca caagtgcacg tttgaagggt gccggaagtc atactcacgc
1021 ctcgaaaacc tgaagacgca cctgcggtca cacacgggtg agaagccata catgtgtgag
1081 cacgagggct gcagtaaagc cttcagcaat gccagtgacc gagccaagca ccagaatcgg
1141 acccattcca atgagaagcc gtatgtatgt aagctccctg gctgcaccaa acgctataca
1201 gatcctagct cgctgcgaaa acatgtcaag acagtgcatg gtcctgacgc ccatgtgacc
1261 aaacggcacc gtggggatgg ccccctgcct cgggcaccat ccatttctac agtggagccc
1321 aagagggagc gggaaggagg tcccatcagg gaggaaagca gactgactgt gccagagggt
1381 gccatgaagc cacagccaag ccctggggcc cagtcatcct gcagcagtga ccactccccg
1441 gcagggagtg cagccaatac agacagtggt gtggaaatga ctggcaatgc agggggcagc
1501 actgaagacc tctccagctt ggacgaggga ccttgcattg ctggcactgg tctgtccact
1561 cttcgccgcc ttgagaacct caggctggac cagctacatc aactccggcc aatagggacc
1621 cggggtctca aactgcccag cttgtcccac accggtacca ctgtgtcccg ccgcgtgggc
1681 cccccagtct ctcttgaacg ccgcagcagc agctccagca gcatcagctc tgcctatact
1741 gtcagccgcc gctcctccct ggcctctcct ttcccccctg gctccccacc agagaatgga
1801 gcatcctccc tgcctggcct tatgcctgcc cagcactacc tgcttcgggc aagatatgct
1861 tcagccagag ggggtggtac ttcgcccact gcagcatcca gcctggatcg gataggtggt
1921 cttcccatgc ctccttggag aagccgagcc gagtatccag gatacaaccc caatgcaggg
1981 gtcacccgga gggccagtga cccagcccag gctgctgacc gtcctgctcc agctagagtc
2041 cagaggttca agagcctggg ctgtgtccat accccaccca ctgtggcagg gggaggacag
2101 aactttgatc cttacctccc aacctctgtc tactcaccac agccccccag catcactgag
2161 aatgctgcca tggatgctag agggctacag gaagagccag aagttgggac ctccatggtg
2221 ggcagtggtc tgaaccccta tatggacttc ccacctactg atactctggg atatggggga
2281 cctgaagggg cagcagctga gccttatgga gcgaggggtc caggctctct gcctcttggg
2341 cctggtccac ccaccaacta tggccccaac ccctgtcccc agcaggcctc atatcctgac
2401 cccacccaag aaacatgggg tgagttccct tcccactctg ggctgtaccc aggccccaag
2461 gctctaggtg gaacctacag ccagtgtcct cgacttgaac attatggaca agtgcaagtc
2521 aagccagaac aggggtgccc agtggggtct gactccacag gactggcacc ctgcctcaat
2581 gcccacccca gtgaggggcc cccacatcca cagcctctct tttcccatta cccccagccc
2641 tctcctcccc aatatctcca gtcaggcccc tatacccagc caccccctga ttatcttcct
2701 tcagaaccca ggccttgcct ggactttgat tcccccaccc attccacagg gcagctcaag
2761 gctcagcttg tgtgtaatta tgttcaatct caacaggagc tactgtggga gggtgggggc
2821 agggaagatg cccccgccca ggaaccttcc taccagagtc ccaagtttct ggggggttcc
2881 caggttagcc caagccgtgc taaagctcca gtgaacacat atggacctgg ctttggaccc
2941 aacttgccca atcacaagtc aggttcctat cccacccctt caccatgcca tgaaaatttt
3001 gtagtggggg caaatagggc ttcacatagg gcagcagcac cacctcgact tctgccccca
3061 ttgcccactt gctatgggcc tctcaaagtg ggaggcacaa accccagctg tggtcatcct
3121 gaggtgggca ggctaggagg gggtcctgcc ttgtaccctc ctcccgaagg acaggtatgt
3181 aaccccctgg actctcttga tcttgacaac actcagctgg actttgtggc tattctggat
3241 gagccccagg ggctgagtcc tcctccttcc catgatcagc ggggcagctc tggacatacc
3301 ccacctccct ctgggccccc caacatggct gtgggcaaca tgagtgtctt actgagatcc
3361 ctacctgggg aaacagaatt cctcaactct agtgcctaaa gagtagggaa tctcatccat
3421 cacagatcgc atttcctaag gggtttctat ccttccagaa aaattggggg agctgcagtc
3481 ccctgcacaa gatgccccag ggatgggagg tatgggctgg gggctatgta tagtctgtat
3541 acgttttgag gagaaatttg ataatgacac tgtttcctga taataaagga actgcatcag
//