LOCUS X04588 2077 bp mRNA linear HUM 18-APR-2005
DEFINITION Human 2.5 kb mRNA for cytoskeletal tropomyosin TM30(nm).
ACCESSION X04588
VERSION X04588.1
KEYWORDS tropomyosin.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2077)
AUTHORS MacLeod A.R., Houlker C., Talbot K.
TITLE The mRNA and RNA-copy pseudogenes encoding TM30nm, a human
cytoskeletal tropomyosin
JOURNAL Nucleic Acids Res. 14(21), 8413-8426(1986).
PUBMED 3024106
COMMENT The structural gene encoding the 2.5 kb mRNA for cytoskeletal
tropomyosin TM30(nm) can also produce a 1,3 kb mRNA encoding a
285 AA skeletal muscle alpha-tropomyosin (ATM) by tissue-specific
alternative mRNA splicing. See x04595; HSTMAR for 1.3 ATM mRNA.
FEATURES Location/Qualifiers
source 1..2077
/db_xref="H-InvDB:HIT000321050"
/organism="Homo sapiens"
/mol_type="mRNA"
/clone_lib="(lambda gt10 cDNA"
/cell_type="fibroblast"
/db_xref="taxon:9606"
CDS 53..799
/note="cytoskeletal tropomyosin (AA 1-248)"
/db_xref="GOA:P06753"
/db_xref="H-InvDB:HIT000321050.13"
/db_xref="HGNC:HGNC:12012"
/db_xref="InterPro:IPR000533"
/db_xref="UniProtKB/Swiss-Prot:P06753"
/protein_id="CAB37185.1"
/translation="MAGITTIEAVKRKIQVLQQQADDAEERAERLQREVEGERRAREQ
AEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKDE
EKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESRCREMDEQ
IRLMDQNLKCLSAAEEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTID
DLEDKLKCTKEEHLCTQRMLDQTLLDLNEM"
misc_feature 191..507
/note="region identical alpha-tropomyosin (see CC)"
misc_feature 581..718
/note="region identical alpha-tropomyosin (see CC)"
BASE COUNT 576 a 457 c 511 g 533 t
ORIGIN
1 cgccgagcga ggaggcagga accggagcgc gagcagtagc tgggtgggca ccatggctgg
61 gatcaccacc atcgaggcgg tgaagcgcaa gatccaggtt ctgcagcagc aggcagatga
121 tgcagaggag cgagctgagc gcctccagcg agaagttgag ggagaaaggc gggcccggga
181 acaggctgag gctgaggtgg cctccttgaa ccgtaggatc cagctggttg aagaagagct
241 ggaccgtgct caggagcgcc tggccactgc cctgcaaaag ctggaagaag ctgaaaaagc
301 tgctgatgag agtgagagag gtatgaaggt tattgaaaac cgggccttaa aagatgaaga
361 aaagatggaa ctccaggaaa tccaactcaa agaagctaag cacattgcag aagaggcaga
421 taggaagtat gaagaggtgg ctcgtaagtt ggtgatcatt gaaggagact tggaacgcac
481 agaggaacga gctgagctgg cagagtcccg ttgccgagag atggatgagc agattagact
541 gatggaccag aacctgaagt gtctgagtgc tgctgaagaa aagtactctc aaaaagaaga
601 taaatatgag gaagaaatca agattcttac tgataaactc aaggaggcag agacccgtgc
661 tgagtttgct gagagatcgg tagccaagct ggaaaagaca attgatgacc tggaagataa
721 actgaaatgc accaaagagg agcacctctg tacacaaagg atgctggacc agaccctgct
781 tgacctgaat gagatgtaga acgcccagtc ccaccctgct gctgctcctc cctctgaccc
841 agactccgcc tgaggccagc ctgcgggaag ctgaccttta actgagggct gatctttaac
901 tggaaggctg ctttctcctt tcaccacccc ctccttccct gtgtcttttt cgccaaactg
961 tctctgcctc ttcccggaga tccagctggg ctagaggctg agcacctttg gaaacaacat
1021 ttaagggaat gtgagcacaa tgcataatgt ctttaaaaag catgttgtga tgtacacatt
1081 ttgtaattac cttttttgtt gttttgtagc aaccatttgt aaaacattcc aaataattcc
1141 acagtcctga agcagcaatc gaatcccttt ctcacttttg gaaggtgact tttcacctta
1201 atgcatattc ccctctccat agaggagagg aaaaggtgta ggcctgcctt accgagagcc
1261 aaacagagcc cagggagact ccgctgtggg aaacctcatt gttctgtaca aagtactagc
1321 taaaccagaa aggtgattcc aggaggagtt agccaaacaa caacaaaaac aaaaaatgtg
1381 ctgttcaagt tttcagcttt aagatatctt tggataatgt tatttctatt ttttattttt
1441 ttcattagaa gttaccaatt aagatggtaa gacctctgag accaaaattt tgtcccatct
1501 ctaccccctc acaactgctt acagaatgga tcatgtcccc cttatgttga ggtgaccact
1561 taattgcttt cctgcctcct tgaaagaaag aaagaaagaa gactgtgttt ttgccactga
1621 tttagccatg tgaaactcat ctcatcaccc ttttctgggt ttgaagctgc tgtctctaga
1681 agtgccatct caattgtgct ttgtatcagt cagtgctgga gaaatcttga atagcttatg
1741 tacaaaactt tttaaatttt atattatttt gaaactttgc tttgggtttg tggcaccctg
1801 gccaccccat ctggctgtga cagcctctgc agtccgtggg ctggcagttt gttgactctt
1861 ttaagtttcc ttccctaccc agtccccatt ttctggtaag gtttctagga ggtctgttag
1921 gtgtacatcc tgcagcttat tggcttaaaa tgtactctcc ttttatgtgg tctctttggg
1981 gccgattggg agaaagagaa atcaatagtg caactgtttt gatactgaat attgacaagt
2041 gtctttttga aataaagaac cagtccctcc aaccctc
//