LOCUS X04299 1457 bp mRNA linear HUM 12-SEP-1993
DEFINITION Human mRNA for liver alcohol dehydrogenase (EC 1.1.1.1) gamma 2
subunit from ADH3 locus.
ACCESSION X04299
VERSION X04299.1
KEYWORDS alcohol dehydrogenase; dehydrogenase.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1457)
AUTHORS Hoeoeg J.O., Heden L.O., Larsson K., Joernvall H.,
Von Bahr-Lindstroem H.
TITLE The gamma-1 and gamma-2 subunits of human liver alcohol
dehydrogenase - cDNA structures, two amino acid replacements, and
compatibility with changes
JOURNAL Eur. J. Biochem. 159, 215-218(1986).
PUBMED 3758060
COMMENT See x04350 for gamma 1 subunit
Data kindly reviewed (20-OCT-1986) by J-O. Hoog
FEATURES Location/Qualifiers
source 1..1457
/db_xref="H-InvDB:HIT000321024"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
CDS 73..1200
/note="gamma 2 subunit (aa 1-375)"
/db_xref="GOA:P00326"
/db_xref="H-InvDB:HIT000321024.12"
/db_xref="HGNC:HGNC:251"
/db_xref="InterPro:IPR002328"
/db_xref="InterPro:IPR011032"
/db_xref="InterPro:IPR013149"
/db_xref="InterPro:IPR013154"
/db_xref="InterPro:IPR020843"
/db_xref="InterPro:IPR036291"
/db_xref="PDB:1DDA"
/db_xref="PDB:1HT0"
/db_xref="PDB:1U3W"
/db_xref="UniProtKB/Swiss-Prot:P00326"
/protein_id="CAA27842.1"
/translation="MSTAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAA
GICRSDEHVVSGNLVTPLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCR
ICKNPESNYCLKNDLGNPRGTLQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAK
IDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAA
RIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGQLDTM
MASLLCCHEACGTSVIVGVPPDSQNLSINPMLLLTGRTWKGAIFGGFKSKESVPKLVA
DFMAKKFSLDALITNVLPFEKINEGFDLLRSGKSIRTVLTF"
misc_feature 1309..1314
/note="pot. polyA signal"
misc_feature 1397..1403
/note="pot. polyA signal"
misc_feature 1434..1439
/note="pot. polyA signal"
polyA_site 1457..1457
/note="polyA site"
BASE COUNT 419 a 313 c 356 g 369 t
ORIGIN
1 gatgcactca agcagagaag aaatccacaa gtactcacca gcctcctggt ctgcagagaa
61 gacagaatca atatgagcac agcaggaaaa gtaatcaaat gcaaagcagc tgtgctatgg
121 gagttaaaga aacccttttc cattgaggag gtagaggttg cacctcctaa ggctcatgaa
181 gttcgcatta agatggtggc tgcaggaatc tgtcgttcag atgagcatgt ggttagtggc
241 aacctggtga ccccccttcc tgtgatttta ggccatgagg cagccggcat cgtggaaagt
301 gttggagaag gggtgactac agtcaaacca ggtgataaag tcatcccgct ctttactcct
361 cagtgtggaa aatgcagaat ttgcaaaaac ccagaaagca actactgctt gaaaaatgat
421 ctaggcaatc ctcgggggac cctgcaggat ggcaccagga ggttcacctg cagcgggaag
481 cccatccacc acttcgtcgg cgtcagcacc ttctcccagt acacagtggt ggatgagaat
541 gcagtagcca aaattgatgc agcctcgccc ctggagaaag tctgcctcat tggctgtgga
601 ttttcgactg gttatgggtc tgcagtcaaa gttgccaagg tcaccccagg gtctacctgt
661 gctgtgtttg gcctgggagg ggtcggccta tctgttgtta tgggctgtaa agcagctgga
721 gcagccagaa tcattgctgt ggacatcaac aaggacaaat ttgcaaaggc taaagagttg
781 ggtgccactg aatgcatcaa ccctcaagac tacaagaaac ccattcagga agtgctaaag
841 gaaatgactg atggaggtgt ggatttttcg tttgaagtca tcggtcagct tgacaccatg
901 atggcttccc tgttatgttg tcatgaggca tgtggcacaa gtgtcattgt aggggtacct
961 cctgattccc agaacctctc aataaaccct atgctgctac tgactggacg cacgtggaaa
1021 ggagctattt ttggaggctt taagagtaaa gaatctgtcc ccaaacttgt ggctgacttt
1081 atggctaaga agttttcact ggatgcatta ataacaaatg ttttaccttt tgaaaaaata
1141 aatgaaggat ttgacctgct tcgctctgga aagagtatcc gtaccgtcct gacgttttga
1201 aacaatacag atgccttccc ttgtagcagt tttcagcctc ctctacccta catgatctgg
1261 agcaacagct aggaaatatc attaattctg ctcttcagag atgttaaaaa taaattacac
1321 gtgggagctt tccaaagaaa tggaaattga tgggaaatta tttgtcaagc aaatgtttaa
1381 aatccaaatg agaactaaat aaagtgttga acatcaactg gggaattgaa gccaataaac
1441 cttccttctt aaccatt
//