LOCUS X03484 2977 bp mRNA linear HUM 07-OCT-2008
DEFINITION Human mRNA for raf oncogene.
ACCESSION X03484
VERSION X03484.1
KEYWORDS oncogene; raf oncogene.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2977)
AUTHORS Bonner T.I., Oppermann H., Seeburg P.H., Kerby S.B., Gunnell M.A.,
Young A.C., Rapp U.R.
TITLE The complete coding sequence of the human raf oncogene and the
corresponding structure of the c-raf-1 gene
JOURNAL Nucleic Acids Res. 14(2), 1009-1015(1986).
PUBMED 3003687
FEATURES Location/Qualifiers
source 1..2977
/db_xref="H-InvDB:HIT000320981"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
CDS 130..2076
/note="raf protein (aa 1-648)"
/db_xref="GOA:P04049"
/db_xref="H-InvDB:HIT000320981.13"
/db_xref="HGNC:HGNC:9829"
/db_xref="InterPro:IPR000719"
/db_xref="InterPro:IPR001245"
/db_xref="InterPro:IPR002219"
/db_xref="InterPro:IPR003116"
/db_xref="InterPro:IPR008271"
/db_xref="InterPro:IPR011009"
/db_xref="InterPro:IPR017441"
/db_xref="InterPro:IPR020454"
/db_xref="InterPro:IPR029071"
/db_xref="PDB:1C1Y"
/db_xref="PDB:1FAQ"
/db_xref="PDB:1FAR"
/db_xref="PDB:1GUA"
/db_xref="PDB:1RFA"
/db_xref="PDB:3CU8"
/db_xref="PDB:3IQJ"
/db_xref="PDB:3IQU"
/db_xref="PDB:3IQV"
/db_xref="PDB:3KUC"
/db_xref="PDB:3KUD"
/db_xref="PDB:3NKX"
/db_xref="PDB:3O8I"
/db_xref="PDB:3OMV"
/db_xref="PDB:4FJ3"
/db_xref="PDB:4G0N"
/db_xref="PDB:4G3X"
/db_xref="PDB:4IEA"
/db_xref="PDB:4IHL"
/db_xref="UniProtKB/Swiss-Prot:P04049"
/protein_id="CAA27204.1"
/translation="MEHIQGAWKTISNGFGFKDAVFDGSSCISPTIVQQFGYQRRASD
DGKLTDPSKTSNTIRVFLPNKQRTVVNVRNGMSLHDCLMKALKVRGLQPECCAVFRLL
HEHKGKKARLDWNTDAASLIGEELQVDFLDHVPLTTHNFARKTFLKLAFCDICQKFLL
NGFRCQTCGYKFHEHCSTKVPTMCVDWSNIRQLLLFPNSTIGDSGVPALPSLTMRRMR
ESVSRMPVSSQHRYSTPHAFTFNTSSPSSEGSLSQRQRSTSTPNVHMVSTTLPVDSRM
IEDAIRSHSESASPSALSSSPNNLSPTGWSQPKTPVPAQRERAPVSGTQEKNKIRPRG
QRDSSYYWEIEASEVMLSTRIGSGSFGTVYKGKWHGDVAVKILKVVDPTPEQFQAFRN
EVAVLRKTRHVNILLFMGYMTKDNLAIVTQWCEGSSLYKHLHVQETKFQMFQLIDIAR
QTAQGMDYLHAKNIIHRDMKSNNIFLHEGLTVKIGDFGLATVKSRWSGSQQVEQPTGS
VLWMAPEVIRMQDNNPFSFQSDVYSYGIVLYELMTGELPYSHINNRDQIIFMVGRGYA
SPDLSKLYKNCPKAMKRLVADCVKKVKEERPLFPQILSSIELLQHSLPKINRSASEPS
LHRAAHTEDINACTLTTSPRLPVF"
misc_feature 2959..2964
/note="pot. polyA signal"
misc_feature 2964..2969
/note="pot. polyA signal"
polyA_site 2977..2977
/note="polyA site"
BASE COUNT 767 a 751 c 725 g 734 t
ORIGIN
1 ccgaatgtga ccgcctcccg ctccctcacc cgccgcgggg aggaggagcg ggcgagaagc
61 tgccgccgaa cgacaggacg ttggggcggc ctggctccct caggtttaag aattgtttaa
121 gctgcatcaa tggagcacat acagggagct tggaagacga tcagcaatgg ttttggattc
181 aaagatgccg tgtttgatgg ctccagctgc atctctccta caatagttca gcagtttggc
241 tatcagcgcc gggcatcaga tgatggcaaa ctcacagatc cttctaagac aagcaacact
301 atccgtgttt tcttgccgaa caagcaaaga acagtggtca atgtgcgaaa tggaatgagc
361 ttgcatgact gccttatgaa agcactcaag gtgaggggcc tgcaaccaga gtgctgtgca
421 gtgttcagac ttctccacga acacaaaggt aaaaaagcac gcttagattg gaatactgat
481 gctgcgtctt tgattggaga agaacttcaa gtagatttcc tggatcatgt tcccctcaca
541 acacacaact ttgctcggaa gacgttcctg aagcttgcct tctgtgacat ctgtcagaaa
601 ttcctgctca atggatttcg atgtcagact tgtggctaca aatttcatga gcactgtagc
661 accaaagtac ctactatgtg tgtggactgg agtaacatca gacaactctt attgtttcca
721 aattccacta ttggtgatag tggagtccca gcactacctt ctttgactat gcgtcgtatg
781 cgagagtctg tttccaggat gcctgttagt tctcagcaca gatattctac acctcacgcc
841 ttcaccttta acacctccag tccctcatct gaaggttccc tctcccagag gcagaggtcg
901 acatccacac ctaatgtcca catggtcagc accacgctgc ctgtggacag caggatgatt
961 gaggatgcaa ttcgaagtca cagcgaatca gcctcacctt cagccctgtc cagtagcccc
1021 aacaatctga gcccaacagg ctggtcacag ccgaaaaccc ccgtgccagc acaaagagag
1081 cgggcaccag tatctgggac ccaggagaaa aacaaaatta ggcctcgtgg acagagagat
1141 tcaagctatt attgggaaat agaagccagt gaagtgatgc tgtccactcg gattgggtca
1201 ggctcttttg gaactgttta taagggtaaa tggcacggag atgttgcagt aaagatccta
1261 aaggttgtcg acccaacccc agagcaattc caggccttca ggaatgaggt ggctgttctg
1321 cgcaaaacac ggcatgtgaa cattctgctt ttcatggggt acatgacaaa ggacaacctg
1381 gcaattgtga cccagtggtg cgagggcagc agcctctaca aacacctgca tgtccaggag
1441 accaagtttc agatgttcca gctaattgac attgcccggc agacggctca gggaatggac
1501 tatttgcatg caaagaacat catccataga gacatgaaat ccaacaatat atttctccat
1561 gaaggcttaa cagtgaaaat tggagatttt ggtttggcaa cagtaaagtc acgctggagt
1621 ggttctcagc aggttgaaca acctactggc tctgtcctct ggatggcccc agaggtgatc
1681 cgaatgcagg ataacaaccc attcagtttc cagtcggatg tctactccta tggcatcgta
1741 ttgtatgaac tgatgacggg ggagcttcct tattctcaca tcaacaaccg agatcagatc
1801 atcttcatgg tgggccgagg atatgcctcc ccagatctta gtaagctata taagaactgc
1861 cccaaagcaa tgaagaggct ggtagctgac tgtgtgaaga aagtaaagga agagaggcct
1921 ctttttcccc agatcctgtc ttccattgag ctgctccaac actctctacc gaagatcaac
1981 cggagcgctt ccgagccatc cttgcatcgg gcagcccaca ctgaggatat caatgcttgc
2041 acgctgacca cgtccccgag gctgcctgtc ttctagttga ctttgcacct gtcttcaggc
2101 tgccagggga ggaggagaag ccagcaggca ccacttttct gctccctttc tccagaggca
2161 gaacacatgt tttcagagaa gctctgctaa ggaccttcta gactgctcac agggccttaa
2221 cttcatgttg ccttcttttc tatccctttg ggccctggga gaaggaagcc atttgcagtg
2281 ctggtgtgtc ctgctccctc cccacattcc ccatgctcaa ggcccagcct tctgtagatg
2341 cgcaagtgga tgttgatggt agtacaaaaa gcaggggccc agccccagct gttggctaca
2401 tgagtattta gaggaagtaa ggtagcaggc agtccagccc tgatgtggag acacatggga
2461 ttttggaaat cagcttctgg aggaatgcat gtcacaggcg ggactttctt cagagagtgg
2521 tgcagcgcca gacattttgc acataaggca ccaaacagcc caggactgcc gagactctgg
2581 ccgcccgaag gagcctgctt tggtactatg gaacttttct taggggacac gtcctccttt
2641 cacagcttct aaggtgtcca gtgcattggg atggttttcc aggcaaggca ctcggccaat
2701 ccgcatctca gccctctcag gagcagtctt ccatcatgct gaattttgtc ttccaggagc
2761 tgcccctatg gggcgggccg cagggccagc ctgtttctct aacaaacaaa caaacaaaca
2821 gccttgtttc tctagtcaca tcatgtgtat acaaggaagc caggaataca ggttttcttg
2881 atgatttggg ttttaatttt gtttttattg cacctgacaa aatacagtta tctgatggtc
2941 cctcaattat gttattttaa taaaataaat taaattt
//