LOCUS X03350 2532 bp mRNA linear HUM 12-SEP-1993
DEFINITION Human mRNA for alcohol dehydrogenase beta-1-subunit (ADH1-2
allele).
ACCESSION X03350
VERSION X03350.1
KEYWORDS alcohol dehydrogenase; dehydrogenase.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2532)
AUTHORS Heden L.O., Hoeoeg J.O., Larsson K., Lake M., Lagerholm E.,
Holmgren A., Vallee B.L., Joernvall H., Von Bahr-Lindstroem H.
TITLE cDNA clones coding for the beta-subunit of human liver alcohol
dehydrogenase have differently sized 3'-non-coding regions
JOURNAL FEBS Lett. 194(2), 327-332(1986).
PUBMED 3000832
COMMENT Data kindly reviewed (20-MAY-1986) by L-O. Heden
FEATURES Location/Qualifiers
source 1..2532
/db_xref="H-InvDB:HIT000320976"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
CDS 73..1200
/note="ADH beta-1-subunit (aa 1-375)"
/db_xref="GOA:P00325"
/db_xref="H-InvDB:HIT000320976.15"
/db_xref="HGNC:HGNC:250"
/db_xref="InterPro:IPR002328"
/db_xref="InterPro:IPR011032"
/db_xref="InterPro:IPR013149"
/db_xref="InterPro:IPR013154"
/db_xref="InterPro:IPR020843"
/db_xref="InterPro:IPR036291"
/db_xref="PDB:1DEH"
/db_xref="PDB:1HDX"
/db_xref="PDB:1HDY"
/db_xref="PDB:1HDZ"
/db_xref="PDB:1HSZ"
/db_xref="PDB:1HTB"
/db_xref="PDB:1U3U"
/db_xref="PDB:1U3V"
/db_xref="PDB:3HUD"
/db_xref="UniProtKB/Swiss-Prot:P00325"
/protein_id="CAA27056.1"
/translation="MSTAGKVIKCKAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAV
GICRTDDHVVSGNLVTPLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCR
VCKNPESNYCLKNDLGNPRGTLQDGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAK
IDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAA
RIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTM
MASLLCCHEACGTSVIVGVPPASQNLSINPMLLLTGRTWKGAVYGGFKSKEGIPKLVA
DFMAKKFSLDALITHVLPFEKINEGFDLLHSGKSIRTVLTF"
misc_feature 1309..1314
/note="put. polyadenylation signal"
misc_feature 1396..1401
/note="polyadenylation signal 1"
polyA_site 1413..1413
/note="polyadenylation site 1"
misc_feature 1651..1656
/note="put. polyadenylation signal"
misc_feature 1767..1773
/note="polyadenylation signal 2"
polyA_site 1790..1790
/note="polyadenylation site 2"
misc_feature 2511..2516
/note="polyadenylation signal 3"
polyA_site 2531..2531
/note="polyadenylation site 3"
BASE COUNT 755 a 490 c 549 g 738 t
ORIGIN
1 agtgcactca agcagagaag aaatccacaa agactcacca gtctgctggt gggcagagaa
61 gacagaaacg acatgagcac agcaggaaaa gtaatcaaat gcaaagcagc tgtgctatgg
121 gaggtaaaga aacccttttc cattgaggat gtggaggttg cacctcctaa ggcttatgaa
181 gttcgcatta agatggtggc tgtaggaatc tgtcgcacag atgaccacgt ggttagtggc
241 aacctggtga ccccccttcc tgtgatttta ggccatgagg cagccggcat cgtggagagt
301 gttggagaag gggtgactac agtcaaacca ggtgataaag tcatcccgct ctttactcct
361 cagtgtggaa aatgcagagt ttgtaaaaac ccggagagca actactgctt gaaaaatgat
421 ctaggcaatc ctcgggggac cctgcaggat ggcaccagga ggttcacctg cagggggaag
481 cccattcacc acttccttgg caccagcacc ttctcccagt acacggtggt ggatgagaat
541 gcagtggcca aaattgatgc agcctcgccc ctggagaaag tctgcctcat tggctgtgga
601 ttctcgactg gttatgggtc tgcagttaac gttgccaagg tcaccccagg ctctacctgt
661 gctgtgtttg gcctgggagg ggtcggccta tctgctgtta tgggctgtaa agcagctgga
721 gcagccagaa tcattgcggt ggacatcaac aaggacaaat ttgcaaaggc caaagagttg
781 ggtgccactg aatgcatcaa ccctcaagac tacaagaaac ccatccagga agtgctaaag
841 gaaatgactg atggaggtgt ggatttttcg tttgaagtca tcggtcggct tgacaccatg
901 atggcttccc tgttatgttg tcatgaggca tgtggcacaa gcgtcatcgt aggggtacct
961 cctgcttccc agaacctctc aataaaccct atgctgctac tgactggacg cacctggaag
1021 ggggctgttt atggtggctt taagagtaaa gaaggtatcc caaaacttgt ggctgatttt
1081 atggctaaga agttttcact ggatgcgtta ataacccatg ttttaccttt tgaaaaaata
1141 aatgaaggat ttgacctgct tcactctggg aaaagtatcc gtaccgtcct gacgttttga
1201 ggcaatagag atgccttccc ctgtagcagt cttcagcctc ctctacccta cgagatctgg
1261 agcaacagct aggaaatatc attaattcag ctcttcagag atgttatcaa taaattacac
1321 atgggggctt tccaaagaaa tggaaattga tgggaaatta tttttcagga aaatttaaaa
1381 ttcaagtcag aagtaaataa agtgttgaac atcagctggg gaattgaagc caacaaacct
1441 tccttcttaa ccattctact gtgtcacctt tgccattgag gaaaaatatt cctgtgactt
1501 cttgcatttt tggtatcttc ataatcttta gtcatcgaat cccagtggag gggacccttt
1561 tacttgccct gaacatacac atgctgggcc attgtgattg aagtcttcta actctgtctc
1621 agttttcact gtcgacattt tcctttttct aataaaaatg taccaaatcc ctggggtaaa
1681 agctagggta aggtaaagga tagactcaca tttacaagta gtgaaggtcc aagagttcta
1741 aatacaggaa atttcttagg aactcaaata aaatgcccac attttactac agtaaatggc
1801 agtgttttta tgacttttat actatttctt tatggtcgat atacaattga ttttttaaaa
1861 taatagcaga tttcttgctt catatgacaa agcctcaatt actaattgta aaaactgaac
1921 tattcccaga atcatgttca aaaaatctgt aattttgctg atgaaagtgc ttcattgact
1981 aaacagtatt agtttgtggc tataaatgat tatttaggat gatgactgaa aatgtgtata
2041 agtaattaaa agtaatatgg tggctttaag tgtagagatg ggatggcaaa tgctgtgaat
2101 gcagaatgta aaattggtaa ctaagaaatg gcacaaacac cttaagcaat atattttcct
2161 agtagatata tatatacaca tacatatata cacatataca aatgtatatt tttgcaaaat
2221 tgttttcaat ctagaacttt tctattaact accatgtctt aaaatcaagt ctataatcct
2281 agcattagtt taatattttg aatatgtaaa gacctgtgtt aatgctttgt taatgctttt
2341 cccactctca tttgttaatg ctttcccact ctcaggggaa ggatttgcat tttgagcttt
2401 atctctaaat gtgacatgca aagattattc ctggtaaagg aggtagctgt ctccaaaaat
2461 gctattgttg caatatctac attctatttc atattatgaa agaccttaga cataaagtaa
2521 aatagtttat ca
//