LOCUS X01098 1611 bp mRNA linear HUM 07-OCT-2008
DEFINITION Human mRNA for aldolase B (EC 4.1.2.13).
ACCESSION X01098 K01177
VERSION X01098.1
KEYWORDS aldolase; aldolase B.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1611)
AUTHORS Paolella G., Santamaria R., Izzo P., Costanzo P., Salvatore F.
TITLE Isolation and nucleotide sequence of a full-length cDNA coding for
aldolase B from human liver
JOURNAL Nucleic Acids Res. 12(19), 7401-7410(1984).
PUBMED 6548561
REFERENCE 2 (bases 777 to 1348)
AUTHORS Besmond C., Dreyfus J.C., Gregori C., Frain M., Zakin M.M.,
Trepat J., Kahn A.
TITLE Nucleotide sequence of a cDNA clone for human aldolase B
JOURNAL Biochem. Biophys. Res. Commun. 117(2), 601-609(1983).
PUBMED 6689266
COMMENT Data kindly reviewed (13-FEB-1986) by C. Besmond
FEATURES Location/Qualifiers
source 1..1611
/db_xref="H-InvDB:HIT000320888"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
CDS 67..1161
/product="aldolase B"
/EC_number="4.1.2.13"
/db_xref="GOA:P05062"
/db_xref="H-InvDB:HIT000320888.13"
/db_xref="HGNC:HGNC:417"
/db_xref="InterPro:IPR000741"
/db_xref="InterPro:IPR013785"
/db_xref="InterPro:IPR029768"
/db_xref="PDB:1QO5"
/db_xref="PDB:1XDL"
/db_xref="PDB:1XDM"
/db_xref="UniProtKB/Swiss-Prot:P05062"
/protein_id="CAA25572.1"
/translation="MAHRFPALTQEQKKELSEIAQSIVANGKGILAADESVGTMGNRL
QRIKVENTEENRRQFREILFSVDSSINQSIGGVILFHETLYQKDSQGKLFRNILKEKG
IVVGIKLDQGGAPLAGTNKETTIQGLDGLSERCAQYKKDGVDFGKWRAVLRIADQCPS
SLAIQENANALARYASICQQNGLVPIVEPEVIPDGDHDLEHCQYVTEKVLAAVYKALN
DHHVYLEGTLLKPNMVTAGHACTKKYTPEQVAMATVTALHRTVPAAVPGICFLSGGMS
EEDATLNLNAINLCPLPKPWKLSFSYGRALQASALAAWGGKAANKEATQEAFMKRAMA
NCQAAKGQYVHTGSSGAASTQSLFTACYTY"
misc_feature 1310..1315
/note="pot. polyadenylation signal"
regulatory 1574..1579
/note="polyadenylation signal"
/regulatory_class="polyA_signal_sequence"
polyA_site 1595..1595
/note="polyadenylation site"
BASE COUNT 465 a 413 c 382 g 351 t
ORIGIN
1 agctgctgcc tcacccacag cttttgcata tctaggagga ctcttctctc ccaaactacc
61 tgtcacatgg cccaccgatt tccagccctc acccaggagc agaagaagga gctctcagaa
121 attgcccaga gcattgttgc caatggaaag gggatcctgg ctgcagatga atctgtaggt
181 accatgggga accgcctgca gaggatcaag gtggaaaaca ctgaagagaa ccgccggcag
241 ttccgagaaa tcctcttctc tgtggacagt tccatcaacc agagcatcgg gggtgtgatc
301 cttttccacg agaccctcta ccagaaggac agccagggaa agctgttcag aaacatcctc
361 aaggaaaagg ggatcgtggt gggaatcaag ttagaccaag gaggtgctcc tcttgcagga
421 acaaacaaag aaaccaccat tcaagggctt gatggcctct cagagcgctg tgctcagtac
481 aagaaagatg gtgttgactt tgggaagtgg cgtgctgtgc tgaggattgc cgaccagtgt
541 ccatccagcc tcgctatcca ggaaaacgcc aacgccctgg ctcgttacgc cagcatctgt
601 cagcagaatg gactggtacc tattgttgaa ccagaggtaa ttcctgatgg agaccatgac
661 ctggaacact gccagtatgt tactgagaag gtcctggctg ctgtctacaa ggccctaaat
721 gaccatcatg tttacctgga gggcaccctg ctaaagccca acatggtgac tgctggacat
781 gcctgcacca agaagtatac tccagaacaa gtagctatgg ccaccgtaac agctctccac
841 cgtactgttc ctgcagctgt tcctggcatc tgctttttgt ctggtggcat gagtgaagag
901 gatgccactc tcaacctcaa tgctatcaac ctttgccctc taccaaagcc ctggaaacta
961 agtttctctt atggacgggc cctgcaggcc agtgcactgg ctgcctgggg tggcaaggct
1021 gcaaacaagg aggcaaccca ggaggctttt atgaagcggg ccatggctaa ctgccaggcg
1081 gccaaaggac agtatgttca cacgggttct tctggggctg cttccaccca gtcgctcttc
1141 acagcctgct atacctacta gggtccaatg cccgccagcc tagctccagt gcttctagta
1201 ggagggctga aagggagcaa cttttcctcc aatcctggaa attcgacaca attagatttg
1261 aactgctgga aatacaacac atgttaaatc ttaagtacaa gggggaaaaa ataaatcagt
1321 tattgaaaca taaaaatgaa taccaaggac ctgatcaaat ttcacacagc gagtttcctt
1381 gcaacacttt cagctcccca tgctccagaa tacccaccca agaaaataac cgggatctaa
1441 aacaataatc ggctcctcat ccaaagaaca actgctgatt gaaacacctc attagctgat
1501 gtagagaagt gcatcttatg aaacagtctt agcagtggta ggttgggaag gagatagctg
1561 caaccaaaaa agaaataaat attctataaa ccttcaaaaa aaaaaaaaaa a
//