LOCUS X00637 1230 bp mRNA linear HUM 18-APR-2005
DEFINITION Human mRNA FOR haptoglobin alpha 1S (Hpa 1S).
ACCESSION X00637
VERSION X00637.1
KEYWORDS glycoprotein; haptoglobin; signal peptide.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1230)
AUTHORS Brune J.L., Yang F., Barnett D.R., Bowman B.H.
TITLE Evolution of haptoglobin: comparison of complementary DNA encoding
Hp alpha 1S and Hp alpha 2FS
JOURNAL Nucleic Acids Res. 12(11), 4531-4538(1984).
PUBMED 6330675
COMMENT Data kindly reviewed (30-JAN-1986) by B.H. Bowman
FEATURES Location/Qualifiers
source 1..1230
/db_xref="H-InvDB:HIT000320875"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
CDS 15..1058
/product="haptoglobin alpha 1S"
/db_xref="GOA:P00738"
/db_xref="H-InvDB:HIT000320875.14"
/db_xref="HGNC:HGNC:5141"
/db_xref="InterPro:IPR000436"
/db_xref="InterPro:IPR001254"
/db_xref="InterPro:IPR001314"
/db_xref="InterPro:IPR009003"
/db_xref="InterPro:IPR035976"
/db_xref="PDB:4WJG"
/db_xref="PDB:4X0L"
/db_xref="PDB:5HU6"
/db_xref="UniProtKB/Swiss-Prot:P00738"
/protein_id="CAA25267.1"
/translation="MSALGAVIALLLWGQLFAVDSGNDVTDIADDGCPKPPEIAHGYV
EHSVRYQCKNYYKLRTEGDGVYTLNNEKQWINKAVGDKLPECEAVCGKPKNPANPVQR
ILGGHLDAKGSFPWQAKMVSHHNLTTGATLINEQWLLTTAKNLFLNHSENATAKDIAP
TLTLYVGKKQLVEIEKVVLHPNYSQVDIGLIKLKQKVSVNERVMPICLPSKDYAEVGR
VGYVSGWGRNANFKFTDHLKYVMLPVADQDQCIRHYEGSTVPEKKTPKSPVGVQPILN
EHTFCAGMSKYQEDTCYGDAGSAFAVHDLEEDTWYATGILSFDKSCAVAEYGVYVKVT
SIQDWVQKTIAEN"
sig_peptide 15..68
/note="signal peptide (aa -18 to -1)"
mat_peptide 69..1055
/note="haptoglobin alpha 1S (aa 1-245)"
BASE COUNT 345 a 278 c 335 g 272 t
ORIGIN
1 caagaccaac caagatgagt gccctgggag ctgtcattgc cctcctgctc tggggacagc
61 tttttgcagt ggactcaggc aatgacgtca cggatatcgc agatgacggc tgcccgaagc
121 cccccgagat tgcacatggc tatgtggagc actcggttcg ctaccagtgt aagaactact
181 acaaactgcg cacagaagga gatggagtgt acaccttaaa caatgagaag cagtggataa
241 ataaggctgt tggagataaa cttcctgaat gtgaagcagt atgtgggaag cccaagaatc
301 cggcaaaccc agtgcagcgg atcctgggtg gacacctgga tgccaaaggc agctttccct
361 ggcaggctaa gatggtttcc caccataatc tcaccacagg tgccacgctg atcaatgaac
421 aatggctgct gaccacggct aaaaatctct tcctgaacca ttcagaaaat gcaacagcga
481 aagacattgc ccctacttta acactctatg tggggaaaaa gcagcttgta gagattgaga
541 aggttgttct acaccctaac tactcccagg tagatattgg gctcatcaaa ctcaaacaga
601 aggtgtctgt taatgagaga gtgatgccca tctgcctacc ttcaaaggat tatgcagaag
661 tagggcgtgt gggttatgtt tctggctggg ggcgaaatgc caattttaaa tttactgacc
721 atctgaagta tgtcatgctg cctgtggctg accaagacca atgcataagg cattatgaag
781 gcagcacagt ccccgaaaag aagacaccga agagccctgt aggggtgcag cccatactga
841 atgaacacac cttctgtgct ggcatgtcta agtaccaaga agacacctgc tatggcgatg
901 cgggcagtgc ctttgccgtt cacgacctgg aggaggacac ctggtatgcg actgggatct
961 taagctttga taagagctgt gctgtggctg agtatggtgt gtatgtgaag gtgacttcca
1021 tccaggactg ggttcagaag accatagctg agaactaatg caaggctggc cggaagccct
1081 tgcctgaaag caagatttca gcctggaaga gggcaaagtg gacgggagtg gacaggagtg
1141 gatgcgataa gatgtggttt gaagctgatg ggtgccagcc ctgcattgct gagtcaatca
1201 ataaagagct ttcttttgac ccaaaaaaaa
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