LOCUS X00265 1665 bp DNA linear HUM 17-NOV-2004
DEFINITION Human chorionic gonadotropin (HCG) gene 5 beta subunit.
ACCESSION X00265 J03720
VERSION X00265.1
KEYWORDS complementary DNA; glycoprotein; gonadotropin; signal peptide.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1665)
AUTHORS Talmadge K., Vamvakopoulos N.C., Fiddes J.C.
TITLE Evolution of the genes for the beta subunits of human chorionic
gonadotropin and luteinizing hormone
JOURNAL Nature 307(5946), 37-40(1984).
PUBMED 6690982
FEATURES Location/Qualifiers
source 1..1665
/organism="Homo sapiens"
/mol_type="genomic DNA"
/db_xref="taxon:9606"
sig_peptide join(552..566,919..963)
intron 567..918
/note="intron I"
CDS join(<964..1086,1321..1635)
/product="beta-gonadotropin"
/db_xref="GOA:P0DN86"
/db_xref="HGNC:HGNC:16452"
/db_xref="HGNC:HGNC:16453"
/db_xref="HGNC:HGNC:1886"
/db_xref="InterPro:IPR001545"
/db_xref="InterPro:IPR006208"
/db_xref="InterPro:IPR018245"
/db_xref="InterPro:IPR029034"
/db_xref="PDB:1HCN"
/db_xref="PDB:1HRP"
/db_xref="PDB:1QFW"
/db_xref="PDB:1XUL"
/db_xref="UniProtKB/Swiss-Prot:P0DN86"
/protein_id="CAA25068.1"
/translation="SKEPLRPRCRPINATLAVEKEGCPVCITVNTTICAGYCPTMTRV
LQGVLPALPQVVCNYRDVRFESIRLPGCPRGVNPVVSYAVALSCQCALCRRSTTDCGG
PKDHPLTCDDPRFQDSSSSKAPPPSLPSPSRLPGPSDTPILPQ"
intron 1087..1320
/note="intron II"
polyA_site 1652..1652
/note="polyadenylation site"
BASE COUNT 278 a 535 c 541 g 311 t
ORIGIN
1 aagggagagg tggggctcgg gctgaatccc tcgttggggg gcatctgggt caagtggctt
61 ccctggcagc acagtcacgg ggaggccctc tctcattggg cagaagctaa gtccgaagcc
121 gcgcccctcc tgggaggttg aactgtggtg caggaaagcc tcaagtagag gagggttgag
181 gcttcaatcc agcactttgc tcgggtcacg gcctcctcct ggctcccagg accccaccat
241 aggcagaggc aggccttcct acaccctact ccctgtgcct ccaggctcga ctagtcccta
301 gcactcgacg actgagtctc tgaggtcact tcaccgtggt ctccgcctca cccttggcgc
361 tggaccagtg agaggagagg gctggggcgc tccgctgagc cactcctgcg cccccctggc
421 cttgtctacc tcttgccccc gaagggttag tgtcgagctc accccagcat cctacaacct
481 cctggtggcc ttgccgcccc cacaaccccg aggtataaag ccaggtacac caggcagggg
541 acgcaccaag gatggagatg ttccaggtaa gactgcaggg cccctgggca ccttccacct
601 ccttccaggc aatcactggc atgagaaggg gcagaccagt gtgagctgtg gaaggaggcc
661 tctttctgga ggagcgtgac ccccagtaag cttcaggtgg ggcagttcct aagggtgggg
721 atctgaaatg ttggggcatc tcaggtcctc tgggctgtgg ggtggactct gaaaggcagg
781 tgtccgggtg gtgggtcctg aataggagat gccgggaagg gtctctgggt ctttgtgggt
841 ggtgtgccac gtgggatggg aaggccgggg ctcggggctg cggtctcaga cccgggtgaa
901 gcagtgtcct tgtcccaggg gctgctgctg ttgctgctgc tgagcatggg cgggacatgg
961 gcatccaagg agccgcttcg gccacggtgc cgccccatca atgccaccct ggctgtggag
1021 aaggagggct gccccgtgtg catcaccgtc aacaccacca tctgtgccgg ctactgcccc
1081 accatggtga gctgcccggg gccggggcag gtgctgccac ctcagggcca gacccacaga
1141 ggcagcgggg gaggaagggt ggtctgcctc tctggtcagg ggctgcggaa tggggtgtgg
1201 gagggcagga acagagggct tcccggaccc ctgagtctga gacctgtggg ggcaactggg
1261 gagctcagct gaggcgctgg cccaggcaca tgctcattcc cccactcaca cggcttccag
1321 acccgcgtgc tgcagggggt cctgccggcc ctgcctcagg tggtgtgcaa ctaccgcgat
1381 gtgcgcttcg agtccatccg gctccctggc tgcccgcgcg gcgtgaaccc cgtggtctcc
1441 tacgccgtgg ctctcagctg tcaatgtgca ctctgccgcc gcagcaccac tgactgcggg
1501 ggtcccaagg accacccctt gacctgtgat gacccccgct tccaggactc ctcttcctca
1561 aaggcccctc cccccagcct tccaagtcca tcccgactcc cggggccctc ggacaccccg
1621 atcctcccac aataaaggct tctcaatccg cactctggag gtgtc
//