LOCUS       X00090                   698 bp    DNA     linear   HUM 12-SEP-1993
DEFINITION  Human histone H3 gene.
ACCESSION   X00090
VERSION     X00090.1
KEYWORDS    histone; histone H3.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 698)
  AUTHORS   Zhong R., Roeder R.G., Heintz N.
  TITLE     The primary structure and expression of four cloned human histone
            genes
  JOURNAL   Nucleic Acids Res. 11(21), 7409-7425(1983).
   PUBMED   6647026
FEATURES             Location/Qualifiers
     source          1..698
                     /organism="Homo sapiens"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:9606"
     regulatory      93..97
                     /note="CAAT box"
                     /regulatory_class="promoter"
     regulatory      114..120
                     /note="TATA box"
                     /regulatory_class="promoter"
     precursor_RNA   148..659
                     /note="put. primary transcript"
     CDS             186..596
                     /note="histone H3"
                     /db_xref="GOA:P68431"
                     /db_xref="HGNC:HGNC:4766"
                     /db_xref="HGNC:HGNC:4767"
                     /db_xref="HGNC:HGNC:4768"
                     /db_xref="HGNC:HGNC:4769"
                     /db_xref="HGNC:HGNC:4771"
                     /db_xref="HGNC:HGNC:4772"
                     /db_xref="HGNC:HGNC:4773"
                     /db_xref="HGNC:HGNC:4774"
                     /db_xref="HGNC:HGNC:4775"
                     /db_xref="HGNC:HGNC:4776"
                     /db_xref="InterPro:IPR000164"
                     /db_xref="InterPro:IPR007125"
                     /db_xref="InterPro:IPR009072"
                     /db_xref="PDB:1CS9"
                     /db_xref="PDB:1CT6"
                     /db_xref="PDB:1O9S"
                     /db_xref="PDB:1Q3L"
                     /db_xref="PDB:2B2T"
                     /db_xref="PDB:2B2U"
                     /db_xref="PDB:2B2V"
                     /db_xref="PDB:2B2W"
                     /db_xref="PDB:2C1J"
                     /db_xref="PDB:2C1N"
                     /db_xref="PDB:2CO0"
                     /db_xref="PDB:2CV5"
                     /db_xref="PDB:2KWJ"
                     /db_xref="PDB:2KWK"
                     /db_xref="PDB:2L75"
                     /db_xref="PDB:2LBM"
                     /db_xref="PDB:2M0O"
                     /db_xref="PDB:2NDF"
                     /db_xref="PDB:2NDG"
                     /db_xref="PDB:2OQ6"
                     /db_xref="PDB:2OT7"
                     /db_xref="PDB:2OX0"
                     /db_xref="PDB:2RI7"
                     /db_xref="PDB:2UXN"
                     /db_xref="PDB:2V85"
                     /db_xref="PDB:2V89"
                     /db_xref="PDB:2VNF"
                     /db_xref="PDB:2VPG"
                     /db_xref="PDB:2X0L"
                     /db_xref="PDB:3A1B"
                     /db_xref="PDB:3AFA"
                     /db_xref="PDB:3AVR"
                     /db_xref="PDB:3AYW"
                     /db_xref="PDB:3AZE"
                     /db_xref="PDB:3AZF"
                     /db_xref="PDB:3AZG"
                     /db_xref="PDB:3AZH"
                     /db_xref="PDB:3AZI"
                     /db_xref="PDB:3AZJ"
                     /db_xref="PDB:3AZK"
                     /db_xref="PDB:3AZL"
                     /db_xref="PDB:3AZM"
                     /db_xref="PDB:3AZN"
                     /db_xref="PDB:3B95"
                     /db_xref="PDB:3KMT"
                     /db_xref="PDB:3KQI"
                     /db_xref="PDB:3LQI"
                     /db_xref="PDB:3LQJ"
                     /db_xref="PDB:3MP1"
                     /db_xref="PDB:3O34"
                     /db_xref="PDB:3O35"
                     /db_xref="PDB:3O37"
                     /db_xref="PDB:3QJ6"
                     /db_xref="PDB:3RIG"
                     /db_xref="PDB:3RIY"
                     /db_xref="PDB:3SOU"
                     /db_xref="PDB:3SOW"
                     /db_xref="PDB:3U31"
                     /db_xref="PDB:3U3D"
                     /db_xref="PDB:3U4S"
                     /db_xref="PDB:3U5N"
                     /db_xref="PDB:3U5O"
                     /db_xref="PDB:3U5P"
                     /db_xref="PDB:3UEE"
                     /db_xref="PDB:3UEF"
                     /db_xref="PDB:3UIG"
                     /db_xref="PDB:3UII"
                     /db_xref="PDB:3UIK"
                     /db_xref="PDB:3V43"
                     /db_xref="PDB:3W96"
                     /db_xref="PDB:3W97"
                     /db_xref="PDB:3W98"
                     /db_xref="PDB:3W99"
                     /db_xref="PDB:3WA9"
                     /db_xref="PDB:3WAA"
                     /db_xref="PDB:3WKJ"
                     /db_xref="PDB:3X1S"
                     /db_xref="PDB:3X1T"
                     /db_xref="PDB:3X1U"
                     /db_xref="PDB:3X1V"
                     /db_xref="PDB:3ZG6"
                     /db_xref="PDB:3ZVY"
                     /db_xref="PDB:4A0J"
                     /db_xref="PDB:4A0N"
                     /db_xref="PDB:4A7J"
                     /db_xref="PDB:4BD3"
                     /db_xref="PDB:4C1Q"
                     /db_xref="PDB:4F4U"
                     /db_xref="PDB:4F56"
                     /db_xref="PDB:4FWF"
                     /db_xref="PDB:4HON"
                     /db_xref="PDB:4I51"
                     /db_xref="PDB:4L7X"
                     /db_xref="PDB:4LK9"
                     /db_xref="PDB:4LKA"
                     /db_xref="PDB:4LLB"
                     /db_xref="PDB:4LXL"
                     /db_xref="PDB:4N4H"
                     /db_xref="PDB:4QBQ"
                     /db_xref="PDB:4QBR"
                     /db_xref="PDB:4QBS"
                     /db_xref="PDB:4TN7"
                     /db_xref="PDB:4U68"
                     /db_xref="PDB:4UP0"
                     /db_xref="PDB:4UY4"
                     /db_xref="PDB:4X3K"
                     /db_xref="PDB:4Y6L"
                     /db_xref="PDB:4YHP"
                     /db_xref="PDB:4YHZ"
                     /db_xref="PDB:4YM5"
                     /db_xref="PDB:4YM6"
                     /db_xref="PDB:4Z0R"
                     /db_xref="PDB:4Z2M"
                     /db_xref="PDB:5AV5"
                     /db_xref="PDB:5AV6"
                     /db_xref="PDB:5AV8"
                     /db_xref="PDB:5AV9"
                     /db_xref="PDB:5AVB"
                     /db_xref="PDB:5AVC"
                     /db_xref="PDB:5B24"
                     /db_xref="PDB:5B2I"
                     /db_xref="PDB:5B2J"
                     /db_xref="PDB:5B31"
                     /db_xref="PDB:5C11"
                     /db_xref="PDB:5C13"
                     /db_xref="PDB:5C3I"
                     /db_xref="PDB:5CPI"
                     /db_xref="PDB:5CPJ"
                     /db_xref="PDB:5CPK"
                     /db_xref="PDB:5D6Y"
                     /db_xref="PDB:5DAH"
                     /db_xref="PDB:5FB0"
                     /db_xref="PDB:5FB1"
                     /db_xref="PDB:5FFV"
                     /db_xref="PDB:5GH9"
                     /db_xref="PDB:5GSE"
                     /db_xref="PDB:5GSU"
                     /db_xref="PDB:5GT0"
                     /db_xref="PDB:5GT3"
                     /db_xref="PDB:5GTC"
                     /db_xref="PDB:5H6Q"
                     /db_xref="PDB:5H6R"
                     /db_xref="PDB:5HJB"
                     /db_xref="PDB:5HJC"
                     /db_xref="PDB:5HJD"
                     /db_xref="PDB:5HYN"
                     /db_xref="PDB:5IQL"
                     /db_xref="PDB:5J3V"
                     /db_xref="PDB:5J9S"
                     /db_xref="PDB:5JHN"
                     /db_xref="PDB:5JIN"
                     /db_xref="PDB:5JIY"
                     /db_xref="PDB:5JJ0"
                     /db_xref="PDB:5JRG"
                     /db_xref="PDB:5KJH"
                     /db_xref="PDB:5KJI"
                     /db_xref="PDB:5KKL"
                     /db_xref="PDB:5LUG"
                     /db_xref="PDB:5M5G"
                     /db_xref="PDB:5MR8"
                     /db_xref="PDB:5NNC"
                     /db_xref="PDB:5NND"
                     /db_xref="PDB:5OY3"
                     /db_xref="PDB:5SVX"
                     /db_xref="PDB:5SVY"
                     /db_xref="PDB:5SZB"
                     /db_xref="PDB:5SZC"
                     /db_xref="PDB:5T0K"
                     /db_xref="PDB:5T0M"
                     /db_xref="PDB:5T1G"
                     /db_xref="PDB:5T1I"
                     /db_xref="PDB:5T8R"
                     /db_xref="PDB:5TBN"
                     /db_xref="PDB:5TDR"
                     /db_xref="PDB:5TDW"
                     /db_xref="PDB:5U2J"
                     /db_xref="PDB:5V21"
                     /db_xref="PDB:5V22"
                     /db_xref="PDB:5VA6"
                     /db_xref="PDB:5VAB"
                     /db_xref="PDB:5VGE"
                     /db_xref="PDB:5VNB"
                     /db_xref="PDB:5WFC"
                     /db_xref="PDB:5WLE"
                     /db_xref="PDB:5WVO"
                     /db_xref="PDB:5WXG"
                     /db_xref="PDB:5WXH"
                     /db_xref="PDB:5WYI"
                     /db_xref="PDB:5X60"
                     /db_xref="PDB:5XF3"
                     /db_xref="PDB:5XF4"
                     /db_xref="PDB:5XF5"
                     /db_xref="PDB:5XFQ"
                     /db_xref="PDB:5XFR"
                     /db_xref="PDB:5XNV"
                     /db_xref="PDB:5XTZ"
                     /db_xref="PDB:5Y0C"
                     /db_xref="PDB:5Y0D"
                     /db_xref="PDB:5Y20"
                     /db_xref="PDB:5Y2F"
                     /db_xref="PDB:5Z23"
                     /db_xref="PDB:5Z30"
                     /db_xref="PDB:6AXJ"
                     /db_xref="PDB:6AZE"
                     /db_xref="PDB:6BHD"
                     /db_xref="PDB:6BHE"
                     /db_xref="PDB:6BHG"
                     /db_xref="PDB:6BHH"
                     /db_xref="PDB:6BHI"
                     /db_xref="PDB:6D07"
                     /db_xref="PDB:6D08"
                     /db_xref="PDB:6E83"
                     /db_xref="PDB:6E86"
                     /db_xref="PDB:6F6D"
                     /db_xref="PDB:6HKT"
                     /db_xref="PDB:6HTS"
                     /db_xref="PDB:6IIS"
                     /db_xref="PDB:6IIT"
                     /db_xref="PDB:6MIL"
                     /db_xref="PDB:6MIM"
                     /db_xref="PDB:6MIN"
                     /db_xref="PDB:6MIO"
                     /db_xref="PDB:6MIQ"
                     /db_xref="PDB:6R8Y"
                     /db_xref="PDB:6R8Z"
                     /db_xref="PDB:6R90"
                     /db_xref="PDB:6R91"
                     /db_xref="PDB:6R92"
                     /db_xref="PDB:6R93"
                     /db_xref="PDB:6R94"
                     /db_xref="UniProtKB/Swiss-Prot:P68431"
                     /protein_id="CAA24952.1"
                     /translation="MARTKQTARKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRP
                     GTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEACEAYLV
                     GLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA"
     regulatory      634..649
                     /note="dyad symmetry"
                     /regulatory_class="other"
BASE COUNT          169 a          183 c          177 g          169 t
ORIGIN      
        1 acggtaatga caggaatctc tcttaatctg caactaggca cagagatggg ccaatccaag
       61 aagggcgcgg ggatttttga attttcttgg gtccaatagt tggtggtctg actctataaa
      121 agaagagtag ctctttcctt tcctccacag acgtctctgc aggcaagctt ttctgtggtt
      181 ttgccatggc tcgtactaaa cagacagctc ggaaatccac cggcggtaaa gcgccacgca
      241 agcagctggc taccaaggct gctcgcaaga gcgcgccggc taccggcggt gtgaaaaagc
      301 ctcaccgtta ccgtccgggt actgtggctc tgcgtgagat ccgccgctac caaaagtcga
      361 ccgagttgct gattcggaag ctgccgttcc agcgcctggt gcgagaaatc gcccaagact
      421 tcaagaccga tcttcgcttc cagagctctg cggtaatggc gctgcaggag gcttgtgagg
      481 cctacttggt agggctcttt gaggacacaa acctttgcgc catccatgct aagcgagtga
      541 ctattatgcc caaagacatc cagctcgctc gccgcattcg cggagaaaga gcgtaaatgt
      601 aaagttactt tttcatcagt cttaaaaccc aaaggctctt ttcagagcca cccacttatt
      661 ccaacgaaag tagctgtgat aattttttgt tgtctcaa
//