LOCUS       X00089                   866 bp    DNA     linear   HUM 18-APR-2005
DEFINITION  Human histone H2a gene.
ACCESSION   X00089
VERSION     X00089.1
KEYWORDS    histone; histone H2A.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 866)
  AUTHORS   Zhong R., Roeder R.G., Heintz N.
  TITLE     The primary structure and expression of four cloned human histone
            genes
  JOURNAL   Nucleic Acids Res. 11(21), 7409-7425(1983).
   PUBMED   6647026
FEATURES             Location/Qualifiers
     source          1..866
                     /organism="Homo sapiens"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:9606"
     regulatory      135..158
                     /note="CAAT box"
                     /regulatory_class="promoter"
     regulatory      173..178
                     /note="TATA box"
                     /regulatory_class="promoter"
     precursor_RNA   207..735
                     /note="put. primary transcript"
     CDS             256..648
                     /note="histone H2a"
                     /db_xref="GOA:P04908"
                     /db_xref="HGNC:HGNC:4724"
                     /db_xref="HGNC:HGNC:4734"
                     /db_xref="InterPro:IPR002119"
                     /db_xref="InterPro:IPR007125"
                     /db_xref="InterPro:IPR009072"
                     /db_xref="InterPro:IPR032454"
                     /db_xref="InterPro:IPR032458"
                     /db_xref="PDB:2CV5"
                     /db_xref="PDB:2RVQ"
                     /db_xref="PDB:3A6N"
                     /db_xref="PDB:3AFA"
                     /db_xref="PDB:3AN2"
                     /db_xref="PDB:3AV1"
                     /db_xref="PDB:3AV2"
                     /db_xref="PDB:3AYW"
                     /db_xref="PDB:3AZE"
                     /db_xref="PDB:3AZF"
                     /db_xref="PDB:3AZG"
                     /db_xref="PDB:3AZH"
                     /db_xref="PDB:3AZI"
                     /db_xref="PDB:3AZJ"
                     /db_xref="PDB:3AZK"
                     /db_xref="PDB:3AZL"
                     /db_xref="PDB:3AZM"
                     /db_xref="PDB:3AZN"
                     /db_xref="PDB:3W96"
                     /db_xref="PDB:3W97"
                     /db_xref="PDB:3W98"
                     /db_xref="PDB:3W99"
                     /db_xref="PDB:3WKJ"
                     /db_xref="PDB:3WTP"
                     /db_xref="PDB:3X1S"
                     /db_xref="PDB:3X1V"
                     /db_xref="PDB:4YM5"
                     /db_xref="PDB:4YM6"
                     /db_xref="PDB:4Z5T"
                     /db_xref="PDB:5AV5"
                     /db_xref="PDB:5AV6"
                     /db_xref="PDB:5AV8"
                     /db_xref="PDB:5AV9"
                     /db_xref="PDB:5AVB"
                     /db_xref="PDB:5AVC"
                     /db_xref="PDB:5AY8"
                     /db_xref="PDB:5B0Y"
                     /db_xref="PDB:5B0Z"
                     /db_xref="PDB:5B24"
                     /db_xref="PDB:5B2I"
                     /db_xref="PDB:5B2J"
                     /db_xref="PDB:5B31"
                     /db_xref="PDB:5B32"
                     /db_xref="PDB:5B40"
                     /db_xref="PDB:5CPI"
                     /db_xref="PDB:5CPJ"
                     /db_xref="PDB:5CPK"
                     /db_xref="PDB:5GSE"
                     /db_xref="PDB:5GTC"
                     /db_xref="PDB:5GXQ"
                     /db_xref="PDB:5JRG"
                     /db_xref="PDB:5X7X"
                     /db_xref="PDB:5XF3"
                     /db_xref="PDB:5XF4"
                     /db_xref="PDB:5XF5"
                     /db_xref="PDB:5Y0C"
                     /db_xref="PDB:5Y0D"
                     /db_xref="PDB:5Z23"
                     /db_xref="PDB:5ZBX"
                     /db_xref="PDB:6A5L"
                     /db_xref="PDB:6A5O"
                     /db_xref="PDB:6A5P"
                     /db_xref="PDB:6A5R"
                     /db_xref="PDB:6A5T"
                     /db_xref="PDB:6A5U"
                     /db_xref="PDB:6BUZ"
                     /db_xref="PDB:6E0C"
                     /db_xref="PDB:6E0P"
                     /db_xref="PDB:6HKT"
                     /db_xref="PDB:6HTS"
                     /db_xref="PDB:6INQ"
                     /db_xref="PDB:6IR9"
                     /db_xref="PDB:6J4W"
                     /db_xref="PDB:6J4X"
                     /db_xref="PDB:6J4Y"
                     /db_xref="PDB:6J4Z"
                     /db_xref="PDB:6J50"
                     /db_xref="PDB:6J51"
                     /db_xref="PDB:6O1D"
                     /db_xref="PDB:6R8Y"
                     /db_xref="PDB:6R8Z"
                     /db_xref="PDB:6R90"
                     /db_xref="PDB:6R91"
                     /db_xref="PDB:6R92"
                     /db_xref="PDB:6R93"
                     /db_xref="PDB:6R94"
                     /db_xref="UniProtKB/Swiss-Prot:P04908"
                     /protein_id="CAA24951.1"
                     /translation="MSGRGKQGGKARAKAKTRSSRAGLQFPVGRVHRLLRKAHYSERV
                     GAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGRVT
                     IAQGGVLPNIQAVLLPKKTESHHKAKGK"
     regulatory      710..725
                     /note="dyad symmetry"
                     /regulatory_class="other"
BASE COUNT          205 a          219 c          209 g          233 t
ORIGIN      
        1 ctagagtgat ctatacacca taaaatagag tatttctcta cacagcccta ctaaaggaat
       61 gagaaagctg tactccacta catactctgg tgtactctgg ctcagttctt ggactcctct
      121 tttcttggcg aactcaactg gtatgaattc ctcacagcct acctccagtc agtataaata
      181 cttctctgcc ttgcgttcta atgtagtttc attacatttt cttgtggcga ttttcccttc
      241 ttatcagaag tagttatgtc tggtcgcggc aaacaaggcg gtaaagctcg cgccaaggca
      301 aagactcggt cttctcgtgc aggtttgcag tttcctgtgg gccgagtgca ccgcctgctc
      361 cgcaaggcac actactccga gcgcgtcggg gctggcgccc cggtgtatct cgcggcggtg
      421 cttgagtacc tgaccgccga gatcctagag ctggcgggca atgcggcccg cgacaacaag
      481 aagacccgca tcatcccgcg ccacctgcaa ttggccatcc gcaatgacga ggagcttaat
      541 aaacttttgg ggcgtgtgac catcgcgcag ggtggcgttt tgcctaatat tcaggcggtg
      601 ctgctgccta agaaaactga gagccatcat aaggccaagg gaaagtgaag agttaacgct
      661 tcatgcactg ctgtttttct gtcagcagac aaaatcagcc taacagcaag gctcttttca
      721 gagccaccta cgacttccat taaatgagct gttgtgcttt ggattatgcc gcccataaag
      781 atgtttttga ggtgttttta atggctttga gtgtggcact tttagtaatt tgtcctgcag
      841 aaattagatc catagaaacc tcagga
//