LOCUS       X00088                   843 bp    DNA     linear   HUM 18-APR-2005
DEFINITION  Human histone H2b gene.
ACCESSION   X00088
VERSION     X00088.1
KEYWORDS    histone; histone H2B.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 843)
  AUTHORS   Zhong R., Roeder R.G., Heintz N.
  TITLE     The primary structure and expression of four cloned human histone
            genes
  JOURNAL   Nucleic Acids Res. 11(21), 7409-7425(1983).
   PUBMED   6647026
FEATURES             Location/Qualifiers
     source          1..843
                     /organism="Homo sapiens"
                     /mol_type="genomic DNA"
                     /db_xref="taxon:9606"
     regulatory      297..303
                     /note="Hogness Box"
                     /regulatory_class="promoter"
     precursor_RNA   324..805
                     /note="primary transcript"
     CDS             370..747
                     /note="histone H2b"
                     /db_xref="GOA:P06899"
                     /db_xref="HGNC:HGNC:4761"
                     /db_xref="InterPro:IPR000558"
                     /db_xref="InterPro:IPR007125"
                     /db_xref="InterPro:IPR009072"
                     /db_xref="PDB:2RVQ"
                     /db_xref="PDB:3A6N"
                     /db_xref="PDB:3AFA"
                     /db_xref="PDB:3AN2"
                     /db_xref="PDB:3AV1"
                     /db_xref="PDB:3AV2"
                     /db_xref="PDB:3AYW"
                     /db_xref="PDB:3AZE"
                     /db_xref="PDB:3AZF"
                     /db_xref="PDB:3AZG"
                     /db_xref="PDB:3AZH"
                     /db_xref="PDB:3AZI"
                     /db_xref="PDB:3AZJ"
                     /db_xref="PDB:3AZK"
                     /db_xref="PDB:3AZL"
                     /db_xref="PDB:3AZM"
                     /db_xref="PDB:3AZN"
                     /db_xref="PDB:3W96"
                     /db_xref="PDB:3W97"
                     /db_xref="PDB:3W98"
                     /db_xref="PDB:3W99"
                     /db_xref="PDB:3WA9"
                     /db_xref="PDB:3WAA"
                     /db_xref="PDB:3WTP"
                     /db_xref="PDB:4CAY"
                     /db_xref="PDB:4YM5"
                     /db_xref="PDB:4YM6"
                     /db_xref="PDB:4Z5T"
                     /db_xref="PDB:5AV5"
                     /db_xref="PDB:5AV6"
                     /db_xref="PDB:5AV8"
                     /db_xref="PDB:5AV9"
                     /db_xref="PDB:5AVB"
                     /db_xref="PDB:5AVC"
                     /db_xref="PDB:5AY8"
                     /db_xref="PDB:5B0Y"
                     /db_xref="PDB:5B0Z"
                     /db_xref="PDB:5B24"
                     /db_xref="PDB:5B2I"
                     /db_xref="PDB:5B2J"
                     /db_xref="PDB:5B31"
                     /db_xref="PDB:5B32"
                     /db_xref="PDB:5B33"
                     /db_xref="PDB:5B40"
                     /db_xref="PDB:5CPI"
                     /db_xref="PDB:5CPJ"
                     /db_xref="PDB:5CPK"
                     /db_xref="PDB:5FUG"
                     /db_xref="PDB:5GSE"
                     /db_xref="PDB:5GTC"
                     /db_xref="PDB:5GXQ"
                     /db_xref="PDB:5JRG"
                     /db_xref="PDB:5VEY"
                     /db_xref="PDB:5X7X"
                     /db_xref="PDB:5XF3"
                     /db_xref="PDB:5XF4"
                     /db_xref="PDB:5XF5"
                     /db_xref="PDB:5Y0C"
                     /db_xref="PDB:5Y0D"
                     /db_xref="PDB:5Z23"
                     /db_xref="PDB:5Z30"
                     /db_xref="PDB:5ZBX"
                     /db_xref="PDB:6A5L"
                     /db_xref="PDB:6A5O"
                     /db_xref="PDB:6A5P"
                     /db_xref="PDB:6A5R"
                     /db_xref="PDB:6A5T"
                     /db_xref="PDB:6A5U"
                     /db_xref="PDB:6BUZ"
                     /db_xref="PDB:6E0C"
                     /db_xref="PDB:6E0P"
                     /db_xref="PDB:6HKT"
                     /db_xref="PDB:6HTS"
                     /db_xref="PDB:6INQ"
                     /db_xref="PDB:6IR9"
                     /db_xref="PDB:6J4W"
                     /db_xref="PDB:6J4X"
                     /db_xref="PDB:6J4Y"
                     /db_xref="PDB:6J4Z"
                     /db_xref="PDB:6J50"
                     /db_xref="PDB:6J51"
                     /db_xref="PDB:6O1D"
                     /db_xref="PDB:6R8Y"
                     /db_xref="PDB:6R8Z"
                     /db_xref="PDB:6R90"
                     /db_xref="PDB:6R91"
                     /db_xref="PDB:6R92"
                     /db_xref="PDB:6R93"
                     /db_xref="PDB:6R94"
                     /db_xref="UniProtKB/Swiss-Prot:P06899"
                     /protein_id="CAA24950.1"
                     /translation="MPEPAKSAPAPKKGSKKAVTKAQKKDGKSAAHRKESYSIYVYKV
                     LKQVHPDTGISSKAMGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLL
                     PGELAKHAVSEGTKAVTKYTSAK"
     regulatory      781..796
                     /note="dyad symmetry pot. transcription termination"
                     /regulatory_class="other"
BASE COUNT          208 a          233 c          207 g          195 t
ORIGIN      
        1 cttggcctta gcgcgggctt tgcctccctg cttgccacgt ccagacatag cgagcgcaac
       61 tcactacgag caaccacaaa gtgaacggga aaggcggcgc tttttataaa cactattggg
      121 cgcgaaaaag aagacgtgtt gttggttggg actgcagttt aatttcaacc aatagtagtg
      181 cgtcttctgg atttgcgaat cctgattggg cagacctgac ctctgacgtt accctgaata
      241 actaccaatc agacacaaga cttcaactct tcaccttatt tgcataagcg attctatata
      301 aaagcgcctt gtcataccct gctcacgctg tttttccttt tcgttggcgc tttatagcta
      361 cacagtgcta tgccagagcc agcgaagtct gctcccgccc cgaaaaaggg ctccaagaag
      421 gcggtgacta aggcgcagaa gaaagacggc aagagcgcag cgcaccgcaa ggagagctat
      481 tccatctatg tgtacaaggt tctgaagcag gtccaccctg acaccggcat ttcgtccaag
      541 gccatgggca tcatgaattc gtttgtgaac gacattttcg agcgcatcgc aggtgaggct
      601 tcccgccttg cgcattacaa caagcgctcg accatcacct ccagggagat ccagacggcc
      661 gtgcgcctgc tgctgcctgg ggagttggcc aagcacgccg tgtccgaggg tactaaggcc
      721 gtcaccaagt acaccagcgc taagtaaaca gtgagttggt tgcaaactct caaccctaac
      781 ggctctttta agagccaccc atgttctcaa agaaagagct ggtgcttgta tttcctcctc
      841 gct
//