LOCUS HSU94333 3460 bp mRNA linear HUM 29-APR-1997
DEFINITION Human Clq/MBL/SPA receptor C1qR(p) mRNA, complete cds.
ACCESSION U94333
VERSION U94333.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3460)
AUTHORS Nepomuceno,R.R., Henschen-Edman,A.H., Burgess,W.H. and Tenner,A.J.
TITLE cDNA cloning and primary structure analysis of C1qR(P), the human
C1q/MBL/SPA receptor that mediates enhanced phagocytosis in vitro
JOURNAL Immunity 6 (2), 119-129 (1997)
PUBMED 9047234
REFERENCE 2 (bases 1 to 3460)
AUTHORS Nepomuceno,R.R., Henschen-Edman,A.H., Burgess,W.H. and Tenner,A.J.
TITLE Direct Submission
JOURNAL Submitted (17-MAR-1997) Molecular Biology and Biochemistry,
University of California, Irvine, 3205 BioSci. II, Irvine, CA
92697-3900, USA
FEATURES Location/Qualifiers
source 1..3460
/db_xref="H-InvDB:HIT000222689"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_line="U937 histiocytic cell line"
CDS 149..2107
/function="mediates enhanced phagocytosis by human
monocytes and macrophages in response to complement C1q,
mannose binding lectin (MBL) and pulmonary surfactant
protein A (SPA)"
/note="Clq/MBL/SPA receptor"
/codon_start=1
/product="C1qR(p)"
/protein_id="AAB53110.1"
/translation="MATSMGLLLLLLLLLTQPGAGTGADTEAVVCVGTACYTAHSGKL
SAAEAQNHCNQNGGNLATVKSKEEAQHVQRVLAQLLRREAALTARMSKFWIGLQREKG
KCLDPSLPLKGFSWVGGGEDTPYSNWHKELRNSCISKRCVSLLLDLSQPLLPNRLPKW
SEGPCGSPGSPGSNIEGFVCKFSFKGMCRPLALGGPGQVTYTTPFQTTSSSLEAVPFA
SAANVACGEGDKDETQSHYFLCKEKAPDVFDWGSSGPLCVSPKYGCNFNNGGCHQDCF
EGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCVLGPHGKNYTCRCPQGY
QLDSSQLDCVDVDECQDSPCAQECVNTPGGFRCECWVGYEPGGPGEGACQDVDECALG
RSPCAQGCTNTDGSFHCSCEEGYVLAGEDGTQCQDVDECVGPGGPLCDSLCFNTQGSF
HCGCLPGWVLAPNGVSCTMGPVSLGPPSGPPDEEDKGEKEGSTVPRAATASPTRGPEG
TPKATPTTSRPSLSSDAPITSAPLKMLAPSGSSGVWREPSIHHATAASGPQEPAGGDS
SVATQNNDGTDGQKLLLFYILGTVVAILLLLALALGLLVYRKRRAKREEKKEKKPQNA
ADSYSWVPERAESRAMENQYSPTPGTDC"
BASE COUNT 764 a 943 c 996 g 757 t
ORIGIN
1 aaagccctca gcctttgtgt ccttctctgc gccggagtgg ctgcagctca cccctcagct
61 ccccttgggg cccagctggg agccgagata gaagctcctg tcgccgctgg gcttctcgcc
121 tcccgcagag ggccacacag agaccgggat ggccacctcc atgggcctgc tgctgctgct
181 gctgctgctc ctgacccagc ccggggcggg gacgggagct gacacggagg cggtggtctg
241 cgtggggacc gcctgctaca cggcccactc gggcaagctg agcgctgccg aggcccagaa
301 ccactgcaac cagaacgggg gcaacctggc cactgtgaag agcaaggagg aggcccagca
361 cgtccagcga gtactggccc agctcctgag gcgggaggca gccctgacgg cgaggatgag
421 caagttctgg attgggctcc agcgagagaa gggcaagtgc ctggacccta gtctgccgct
481 gaagggcttc agctgggtgg gcggggggga ggacacgcct tactctaact ggcacaagga
541 gctccggaac tcgtgcatct ccaagcgctg tgtgtctctg ctgctggacc tgtcccagcc
601 gctccttccc aaccgcctgc ccaagtggtc tgagggcccc tgtgggagcc caggctcccc
661 cggaagtaac attgagggct tcgtgtgcaa gttcagcttc aaaggcatgt gccggcctct
721 ggccctgggg ggcccaggtc aggtgaccta caccaccccc ttccagacca ccagttcctc
781 cttggaggct gtgccctttg cctctgcggc caatgtagcc tgtggggaag gtgacaagga
841 cgagactcag agtcattatt tcctgtgcaa ggagaaggcc cccgatgtgt tcgactgggg
901 cagctcgggc cccctctgtg tcagccccaa gtatggctgc aacttcaaca atgggggctg
961 ccaccaggac tgctttgaag ggggggatgg ctccttcctc tgcggctgcc gaccaggatt
1021 ccggctgctg gatgacctgg tgacctgtgc ctctcgaaac ccttgcagct ccagcccatg
1081 tcgtgggggg gccacgtgcg tcctgggacc ccatgggaaa aactacacgt gccgctgccc
1141 ccaagggtac cagctggact cgagtcagct ggactgtgtg gacgtggatg aatgccagga
1201 ctccccctgt gcccaggagt gtgtcaacac ccctgggggc ttccgctgcg aatgctgggt
1261 tggctatgag ccgggcggtc ctggagaggg ggcctgtcag gatgtggatg agtgtgctct
1321 gggtcgctcg ccttgcgccc agggctgcac caacacagat ggctcatttc actgctcctg
1381 tgaggagggc tacgtcctgg ccggggagga cgggactcag tgccaggacg tggatgagtg
1441 tgtgggcccg gggggccccc tctgcgacag cttgtgcttc aacacacaag ggtccttcca
1501 ctgtggctgc ctgccaggct gggtgctggc cccaaatggg gtctcttgca ccatggggcc
1561 tgtgtctctg ggaccaccat ctgggccccc cgatgaggag gacaaaggag agaaagaagg
1621 gagcaccgtg ccccgcgctg caacagccag tcccacaagg ggccccgagg gcacccccaa
1681 ggctacaccc accacaagta gaccttcgct gtcatctgac gcccccatca catctgcccc
1741 actcaagatg ctggccccca gtgggtcctc aggcgtctgg agggagccca gcatccatca
1801 cgccacagct gcctctggcc cccaggagcc tgcaggtggg gactcctccg tggccacaca
1861 aaacaacgat ggcactgacg ggcaaaagct gcttttattc tacatcctag gcaccgtggt
1921 ggccatccta ctcctgctgg ccctggctct ggggctactg gtctatcgca agcggagagc
1981 gaagagggag gagaagaagg agaagaagcc ccagaatgcg gcagacagtt actcctgggt
2041 tccagagcga gctgagagca gggccatgga gaaccagtac agtccgacac ctgggacaga
2101 ctgctgaaag tgaggtggcc ctagagacac tagagtcacc agccaccatc ctcagagctt
2161 tgaactcccc attccaaagg ggcacccaca tttttttgaa agactggact ggaatcttag
2221 caaacaattg taagtctcct ccttaaaggc cccttggaac atgcaggtat tttctacggg
2281 tgtttgatgt tcctgaagtg gaagctgtgt gttggcgtgc cacggtgggg atttcgtgac
2341 tctataatga ttgttactcc ccctcccttt tcaaattcca atgtgaccaa ttccggatca
2401 gggtgtgagg aggctggggc taaggggctc ccctgaatat cttctctgct cacttccacc
2461 atctaagagg aaaaggtgag ttgctcatgc tgattaggat tgaaatgatt tgtttctctt
2521 cctaggatga aaactaaatc aattaattat tcaattaggt aagaagatct ggttttttgg
2581 tcaaagggaa catgttcgga ctggaaacat ttctttacat ttgcattcct ccatttcgcc
2641 agcacaagtc ttgctaaatg tgatactgtt gacatcctcc agaatggcca gaagtgcaat
2701 taacctctta ggtggcaagg aggcaggaag tgcctcttta gttcttacat ttctaatagc
2761 cttgggttta tttgcaaagg aagcttgaaa aatatgagaa aagttgcttg aagtgcatta
2821 caggtgtttg tgaagtcaca taatctacgg ggctagggcg agagaggcca gggatttgtt
2881 cacagatact tgaattaatt catccaaatg tactgaggtt accacacact tgactacgga
2941 tgtgatcaac actaacaagg aaacaaattc aaggacaacc tgtctttgag ccagggcagg
3001 cctcagacac cctgcctgtg gccccgcctc cacttcatcc tgcccggaat gccagtgctc
3061 cgagctcaga cagaggaagc cctgcagaaa gttccatcag gctgtttcct aaaggatgtg
3121 tgaacgggag atgatgcact gtgttttgaa agttgtcatt ttaaagcatt ttagcacagt
3181 tcatagtcca cagttgatgc agcatcctga gattttaaat cctgaagtgt gggtggcgca
3241 cacaccaagt agggagctag tcaggcagtt tgcttaagga acttttgttc tctgtctctt
3301 ttccttaaaa ttgggggtaa ggagggaagg aagagggaaa gagatgacta actaaaatca
3361 tttttacagc aaaaactgct caaagccatt taaattatat cctcatttta aaagttacat
3421 ttgcaaatat ttctccctat gataatgcag tcgatagtgt
//