LOCUS HSU93850 2178 bp mRNA linear HUM 25-MAY-1997
DEFINITION Homo sapiens elongation factor-2 kinase mRNA, complete cds.
ACCESSION U93850
VERSION U93850.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2178)
AUTHORS Ryazanov,A.G., Ward,M.D., Mendola,C.E., Pavur,K.S., Dorovkov,M.V.,
Wiedmann,M., Erdjument-Bromage,H., Tempst,P., Parmer,T.G.,
Prostko,C.R., Germino,F.J. and Hait,W.N.
TITLE Identification of a new class of protein kinases represented by
eukaryotic elongation factor-2 kinase
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 94 (10), 4884-4889 (1997)
PUBMED 9144159
REFERENCE 2 (bases 1 to 2178)
AUTHORS Ryazanov,A.G., Ward,M.D., Mendola,C.E., Pavur,K.S., Dorovkov,M.V.,
Wiedmann,M., Erdjument-Bromage,H., Tempst,P., Parmer,T.G.,
Prostko,C.R., Germino,F.J. and Hait,W.N.
TITLE Direct Submission
JOURNAL Submitted (17-MAR-1997) Pharmacology, Robert Wood Johnson Medical
School-UMDNJ, 675 Hoes Lane, Piscataway, NJ 08854, USA
FEATURES Location/Qualifiers
source 1..2178
/db_xref="H-InvDB:HIT000222677"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_line="T98G"
/cell_type="glioma"
CDS 1..2178
/function="protein kinase"
/codon_start=1
/product="elongation factor-2 kinase"
/protein_id="AAB58270.1"
/translation="MADEDLIFRLEGVDGGQSPRAGHDGDSDGDSDDEEGYFICPITD
DPSSNQNVNSKVNKYYSNLTKSERYSSSGSPANSFHFKEAWKHAIQKAKHMPDPWAEF
HLEDIATERATRHRYNAVTGEWLDDEVLIKMASQPFGRGAMRECFRTKKLSNFLHAQQ
WKGASNYVAKRYIEPVDRDVYFEDVRLQMEAKLWGEEYNRHKPPKQVDIMQMCIIELK
DRPGKPLFHLEHYIEGKYIKYNSNSGFVRDDNIRLTPQAFSHFTFERSGHQLIVVDIQ
GVGDLYTDPQIHTETGTDFGDGNLGVRGMALFFYSHACNRICESMGLAPFDLSPRERD
AVNQNTKLLQSAKTILRGTEEKCGSPRVRTLSGSRPPLLRPLSENSGDENMSDVTFDS
LPSSPSSATPHSQKLDHLHWPVFSDLDNMASRDHDHLDNHRESENSGDSGYPSEKRGE
LDDPEPREHGHSYSNRKYESDEDSLGSSGRVCVEKWNLLNSSRLHLPRASAVALEVQR
LNALDLEKKIGKSILGKVHLAMVRYHEGGRFCEKGEEWDQESAVFHLEHAANLGELEA
IVGLGLMYSQLPHHILADVSLKETEENKTKGFDYLLKAAEAGDRQSMILVARAFDSGQ
NLSPDRCQDWLEALHWYNTALEMTDCDEGGEYDGMQDEPRYMMLAREAEMLFTGGYGL
EKDPQRSGDLYTQAAEAAMEAMKGRLANQYYQKAEEAWAQMEE"
BASE COUNT 541 a 607 c 637 g 393 t
ORIGIN
1 atggcagacg aagacctcat cttccgcctg gaaggtgttg atggcggcca gtccccccga
61 gctggccatg atggtgattc tgatggggac agcgacgatg aggaaggtta cttcatctgc
121 cccatcacgg atgacccaag ctcgaaccag aatgtcaatt ccaaggttaa taagtactac
181 agcaacctaa caaaaagtga gcggtatagc tccagcgggt ccccggcaaa ctccttccac
241 ttcaaggaag cctggaagca cgcaatccag aaggccaagc acatgcccga cccctgggct
301 gagttccacc tggaagatat tgccaccgaa cgtgctactc gacacaggta caacgccgtc
361 accggggaat ggctggatga tgaagttctg atcaagatgg catctcagcc cttcggccga
421 ggagcaatga gggagtgctt ccggacgaag aagctctcca acttcttgca tgcccagcag
481 tggaagggcg cctccaacta cgtggcgaag cgctacatcg agcccgtaga ccgggatgtg
541 tactttgagg acgtgcgtct acagatggag gccaagctct ggggggagga gtataatcgg
601 cacaagcccc ccaagcaggt ggacatcatg cagatgtgca tcatcgagct gaaggacaga
661 ccgggcaagc ccctcttcca cctggagcac tacatcgagg gcaagtacat caagtacaac
721 tccaactctg gctttgtccg tgatgacaac atccgactga cgccgcaggc cttcagccac
781 ttcacttttg agcgttccgg ccatcagctg atagtggtgg acatccaggg agttggggat
841 ctctacactg acccacagat ccacacggag acgggcactg actttggaga cggcaaccta
901 ggtgtccgcg ggatggcgct cttcttctac tctcatgcct gcaaccggat ttgcgagagc
961 atgggccttg ctccctttga cctctcgccc cgggagaggg atgcagtgaa tcagaacacc
1021 aagctgctgc aatcagccaa gaccatcttg agaggaacag aggaaaaatg tgggagcccc
1081 cgagtaagga ccctctctgg gagccggcca cccctgctcc gtcccctttc agagaactct
1141 ggagacgaga acatgagcga cgtgaccttc gactctctcc cttcttcccc atcttcggcc
1201 acaccacaca gccagaagct agaccacctc cattggccag tgttcagtga cctcgataac
1261 atggcatcca gagaccatga tcatctagac aaccaccggg agtctgagaa tagtggggac
1321 agcggatacc ccagtgagaa gcggggtgag ctggatgacc ctgagccccg agaacatggc
1381 cactcataca gtaatcggaa gtacgagtct gacgaagaca gcctgggcag ctctggacgg
1441 gtatgtgtag agaagtggaa tctcctcaac tcctcccgcc tccacctgcc gagggcttcg
1501 gccgtggccc tggaagtgca aaggcttaat gctctggacc tcgaaaagaa aatcgggaag
1561 tccattttgg ggaaggtcca tctggccatg gtgcgctacc acgagggtgg gcgcttctgc
1621 gagaagggcg aggagtggga ccaggagtcg gctgtcttcc acctggagca cgcagccaac
1681 ctgggcgagc tggaggccat cgtgggcctg ggactcatgt actcgcagtt gcctcatcac
1741 atcctagccg atgtctctct gaaggagaca gaagagaaca aaaccaaagg atttgattac
1801 ttactaaagg ccgctgaagc tggcgacagg cagtccatga tcctagtggc gcgagctttt
1861 gactctggcc agaacctcag cccggacagg tgccaagact ggctagaggc cctgcactgg
1921 tacaacactg ccctggagat gacggactgt gatgagggcg gtgagtacga cggaatgcag
1981 gacgagcccc ggtacatgat gctggccagg gaggcagaga tgctgttcac aggaggctac
2041 gggctggaga aggacccgca gagatcaggg gacttgtata cccaggcagc agaggcagcg
2101 atggaagcca tgaagggccg actggccaac cagtactacc aaaaggctga agaggcctgg
2161 gcccagatgg aggaataa
//