LOCUS HSU93049 2400 bp mRNA linear HUM 14-MAY-1997
DEFINITION Human SLP-76 associated protein mRNA, complete cds.
ACCESSION U93049
VERSION U93049.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2400)
AUTHORS Musci,M.A., Hendricks-Taylor,L.R., Motto,D.G., Paskind,M.,
Kamens,J., Turck,C.W. and Koretzky,G.A.
TITLE Molecular cloning of SLAP-130, an SLP-76-associated substrate of
the T cell antigen receptor-stimulated protein tyrosine kinases
JOURNAL J. Biol. Chem. 272 (18), 11674-11677 (1997)
PUBMED 9115214
REFERENCE 2 (bases 1 to 2400)
AUTHORS Musci,M.A., Hendricks-Taylor,L.R., Motto,D.G., Paskind,M.,
Kamens,J., Turck,C.W. and Koretzky,G.A.
TITLE Direct Submission
JOURNAL Submitted (11-MAR-1997) Internal Medicine, University of Iowa, 540
EMRB, Iowa City, IA 52242, USA
FEATURES Location/Qualifiers
source 1..2400
/db_xref="H-InvDB:HIT000222657"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_line="Jurkat"
/cell_type="T cell"
CDS 31..2382
/note="SLAP-130; 130 kDa"
/codon_start=1
/product="SLP-76 associated protein"
/protein_id="AAC51300.1"
/translation="MAKYNTGGNPTEDVSVNSRPFRVTGPNSSSGIQARKNLFNNQGN
ASPPAGPSNVPKFGSPKPPVAVKPSSEEKPDKEPKPPFLKPTGAGQRFGTPASLTTRD
PEAKVGFLKPVGPKPINLPKEDSKPTFPWPPGNKPSLHSVNQDHDLKPLGPKSGPTPP
TSENEQKQAFPKLTGVKGKFMSASQDLEPKPLFPKPAFGQKPPLSTENSHEDESPMKN
VSSSKGSPAPLGVRSKSGPLKPAREDSENKDHAGEISSLPFPGVVLKPAASRGGLGLS
KNGEEKKEDRKIDAAKNTFQSKINQEELASGTPPARFPKAPSKLTVGGPWGQSQEKEK
GDKNSATPKQKPLPPLFTLGPPPPKPNRPPNVDLTKFHKTSSGNSTSKGQTSYSTTSL
PPPPPSHPASQPPLPASHPSQPPVPSLPPRNIKPPFDLKSPVNEDNQDGVTHSDGAGN
LDEEQDSEGETYEDIEASKEREKKREKEEKKRLELEKKEQKEKEKKEQEIKKKFKLTG
PIQVIHLAKACCDVKGGKNELSFKQGEQIEIIRITDNPEGKWLGRTARGSYGYIKTTA
VEIDYDSLKLKKDSLGAPSRPIEDDQEVYDDVAEQDDISSHSQSGSGGIFPPPPDDDI
YDGIEEEDADDGFPAPPKQLDMGDEVYDDVDTSDFPVSSAEMSQGTNFGKAKTEEKDL
KKLKKQEKEEKDFRKKFKYDGEIRVLYSTKVTTSITSKKWGTRDLQVKPGESLEVIQT
TDDTKVLCRNEEGKYGYVLRSYLADNDGEIYDDIADGCIYDND"
misc_feature 31..1350
/note="encodes a proline rich region"
misc_feature 1468..1539
/note="encodes putative nuclear localization site"
misc_feature 2077..2133
/note="encodes putative nuclear localization site"
BASE COUNT 835 a 562 c 534 g 469 t
ORIGIN
1 taggatggaa aggcagatgt aaagtccctc atggcgaaat ataacacggg gggcaacccg
61 acagaggatg tctcagtcaa tagccgaccc ttcagagtca cagggccaaa ctcatcttca
121 ggaatacaag caagaaagaa cttattcaac aaccaaggaa atgccagccc tcctgcagga
181 cccagcaatg tacctaagtt tgggtcccca aagccacctg tggcagtcaa accttcttct
241 gaggaaaagc ctgacaagga acccaagccc ccgtttctaa agcccactgg agcaggccaa
301 agattcggaa caccagccag cttgaccacc agagaccccg aggcgaaagt gggatttctg
361 aaacctgtag gccccaagcc catcaacttg cccaaagaag attccaaacc tacatttccc
421 tggcctcctg gaaacaagcc atctcttcac agtgtaaacc aagaccatga cttaaagcca
481 ctaggcccga aatctgggcc tactcctcca acctcagaaa atgaacagaa gcaagcgttt
541 cccaaattga ctggggttaa agggaaattt atgtcagcat cacaagatct tgaacccaag
601 cccctcttcc ccaaacccgc ctttggccag aagccgcccc taagtaccga gaactcccat
661 gaagacgaaa gccccatgaa gaatgtgtct tcatcaaaag ggtccccagc tcccctggga
721 gtcaggtcca aaagcggccc tttaaaacca gcaagggaag actcagaaaa taaagaccat
781 gcaggggaga tttcaagttt gccctttcct ggagtggttt tgaaacctgc tgcgagcagg
841 ggaggcctag gtctctccaa aaatggtgaa gaaaaaaagg aagataggaa gatagatgct
901 gctaagaaca ccttccagag caaaataaat caggaagagt tggcctcagg gactcctcct
961 gccaggttcc ctaaggcccc ttctaagctg acagtggggg ggccatgggg ccaaagtcag
1021 gaaaaggaaa agggagacaa gaattcagcc accccgaaac agaagccatt gcctcccttg
1081 tttaccttgg gtccacctcc accaaaaccc aacagaccac caaatgttga cctgacgaaa
1141 ttccacaaaa cctcttctgg aaacagtact agcaaaggcc agacgtctta ctcaacaact
1201 tccctgccac cacctccacc atcccatccg gccagccaac caccattgcc agcatctcac
1261 ccatcacaac caccagtccc aagcctacct cccagaaaca ttaaacctcc gtttgaccta
1321 aaaagccctg tcaatgaaga caatcaagat ggtgtcacgc actctgatgg tgctggaaat
1381 ctagatgagg aacaagacag tgaaggagaa acatatgaag acatagaagc atccaaagaa
1441 agagagaaga aaagggaaaa ggaagaaaag aagaggttag agctggagaa aaaggaacag
1501 aaagagaaag aaaagaaaga acaagaaata aagaagaaat ttaaactaac aggccctatt
1561 caagtcatcc atcttgcaaa agcttgttgt gatgtcaaag gaggaaagaa tgaactgagc
1621 ttcaagcaag gagagcaaat tgaaatcatc cgcatcacag acaacccaga aggaaaatgg
1681 ttgggcagaa cagcaagggg ttcatatggc tatattaaaa caactgctgt agagattgac
1741 tatgattctt tgaaactgaa aaaagactct cttggtgccc cttcaagacc tattgaagat
1801 gaccaagaag tatatgatga tgttgcagag caggatgata ttagcagcca cagtcagagt
1861 ggaagtggag ggatattccc tccaccacca gatgatgaca tttatgatgg gattgaagag
1921 gaagatgctg atgatggttt ccctgctcct cctaaacaat tggacatggg agatgaagtt
1981 tacgatgatg tggatacctc tgatttccct gtttcatcag cagagatgag tcaaggaact
2041 aattttggaa aagctaagac agaagaaaag gaccttaaga agctaaaaaa gcaggaaaaa
2101 gaagaaaaag acttcaggaa aaaatttaaa tatgatggtg aaattagagt cctatattca
2161 actaaagtta caacttccat aacttctaaa aagtggggaa ccagagatct acaggtaaaa
2221 cctggtgaat ctctagaagt tatacaaacc acagatgaca caaaagttct ctgcagaaat
2281 gaagaaggga aatatggtta tgtccttcgg agttacctag cggacaatga tggagagatc
2341 tatgatgata ttgctgatgg ctgcatctat gacaatgact agcactcaac tttggtcatt
//