LOCUS HSU92457 3431 bp mRNA linear HUM 07-JUL-1999
DEFINITION Human metabotropic glutamate receptor 4 mRNA, complete cds.
ACCESSION U92457
VERSION U92457.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3431)
AUTHORS Wu,S., Wright,R.A., Rockey,P.K., Burgett,S.G., Arnold,J.S.,
Rosteck,P.R. Jr., Johnson,B.G., Schoepp,D.D. and Belagaje,R.M.
TITLE Group III human metabotropic glutamate receptors 4, 7 and 8:
molecular cloning, functional expression, and comparison of
pharmacological properties in RGT cells
JOURNAL Brain Res. Mol. Brain Res. 53 (1-2), 88-97 (1998)
PUBMED 9473604
REFERENCE 2 (bases 1 to 3431)
AUTHORS Wu,S. and Belagaje,R.M.
TITLE Direct Submission
JOURNAL Submitted (07-MAR-1997) mc625, Eli Lilly and Company, Lilly
Corporate Center, Indianapolis, IN 46285, USA
FEATURES Location/Qualifiers
source 1..3431
/db_xref="H-InvDB:HIT000222624"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="HmGluR4-13"
CDS 26..2764
/note="HmGluR4; Group III"
/codon_start=1
/product="metabotropic glutamate receptor 4"
/protein_id="AAB51762.1"
/translation="MPGKRGLGWWWARLPLCLLLSLYGPWMPSSLGKPKGHPHMNSIR
IDGDITLGGLFPVHGRGSEGKPCGELKKEKGIHRLEAMLFALDRINNDPDLLPNITLG
ARILDTCSRDTHALEQSLTFVQALIEKDGTEVRCGSGGPPIITKPERVVGVIGASGSS
VSIMVANILRLFKIPQISYASTAPDLSDNSRYDFFSRVVPSDTYQAQAMVDIVRALKW
NYVSTVASEGSYGESGVEAFIQKSREDGGVCIAQSVKIPREPKAGEFDKIIRRLLETS
NARAVIIFANEDDIRRVLEAARRANQTGHFFWMGSDSWGSKIAPVLHLEEVAEGAVTI
LPKRMSVRGFDRYFSSRTLDNNRRNIWFAEFWEDNFHCKLSRHALKKGSHVKKCTNRE
RIGQDSAYEQEGKVQFVIDAVYAMGHALHAMHRDLCPGRVGLCPRMDPVDGTQLLKYI
RNVNFSGIAGNPVTFNENGDAPGRYDIYQYQLRNDSAEYKVIGSWTDHLHLRIERMHW
PGSGQQLPRSICSLPCQPGERKKTVKGMPCCWHCEPCTGYQYQVDRYTCKTCPYDMRP
TENRTGCRPIPIIKLEWGSPWAVLPLFLAVVGIAATLFVVITFVRYNDTPIVKASGRE
LSYVLLAGIFLCYATTFLMIAEPDLGTCSLRRIFLGLGMSISYAALLTKTNRIYRIFE
QGKRSVSAPRFISPASQLAITFSLISLQLLGICVWFVVDPSHSVVDFQDQRTLDPRFA
RGVLKCDISDLSLICLLGYSMLLMVTCTVYAIKTRGVPETFNEAKPIGFTMYTTCIVW
LAFIPIFFGTSQSADKLYIQTTTLTVSVSLSASVSLGMLYMPKVYIILFHPEQNVPKR
KRSLKAVVTAATMSNKFTQKGNFRPNGEAKSELCENLEAPALATKQTYVTYTNHAI"
BASE COUNT 649 a 1126 c 950 g 706 t
ORIGIN
1 tcatgggtct ctagggattt ccgaaatgcc tgggaagaga ggcttgggct ggtggtgggc
61 ccggctgccc ctttgcctgc tcctcagcct ttacggcccc tggatgcctt cctccctggg
121 aaagcccaaa ggccaccctc acatgaattc catccgcata gatggggaca tcacactggg
181 aggcctgttc ccggtgcatg gccggggctc agagggcaag ccctgtggag aacttaagaa
241 ggaaaagggc atccaccggc tggaggccat gctgttcgcc ctggatcgca tcaacaacga
301 cccggacctg ctgcctaaca tcacgctggg cgcccgcatt ctggacacct gctccaggga
361 cacccatgcc ctcgagcagt cgctgacctt tgtgcaggcg ctcatcgaga aggatggcac
421 agaggtccgc tgtggcagtg gcggcccacc catcatcacc aagcctgaac gtgtggtggg
481 tgtcatcggt gcttcaggga gctcggtctc catcatggtg gccaacatcc ttcgcctctt
541 caagataccc cagatcagct acgcctccac agcgccagac ctgagtgaca acagccgcta
601 cgacttcttc tcccgcgtgg tgccctcgga cacgtaccag gcccaggcca tggtggacat
661 cgtccgcgcc ctcaagtgga actatgtgtc cacagtggcc tcggagggca gctatggtga
721 gagcggtgtg gaggccttca tccagaagtc ccgtgaggac gggggcgtgt gcatcgccca
781 gtcggtgaag ataccacggg agcccaaggc aggcgagttc gacaagatca tccgccgcct
841 cctggagact tcgaacgcca gggcagtcat catctttgcc aacgaggatg acatcaggcg
901 tgtgctggag gcagcacgaa gggccaacca gacaggccat ttcttctgga tgggctctga
961 cagctggggc tccaagattg cacctgtgct gcacctggag gaggtggctg agggtgctgt
1021 cacgatcctc cccaagagga tgtccgtacg aggcttcgac cgctacttct ccagccgcac
1081 gctggacaac aaccggcgca acatctggtt tgccgagttc tgggaggaca acttccactg
1141 caagctgagc cgccacgccc tcaagaaggg cagccacgtc aagaagtgca ccaaccgtga
1201 gcgaattggg caggattcag cttatgagca ggaggggaag gtgcagtttg tgatcgatgc
1261 cgtgtacgcc atgggccacg cgctgcacgc catgcaccgt gacctgtgtc ccggccgcgt
1321 ggggctctgc ccgcgcatgg accctgtaga tggcacccag ctgcttaagt acatccgaaa
1381 cgtcaacttc tcaggcatcg cagggaaccc tgtgaccttc aatgagaatg gagatgcgcc
1441 tgggcgctat gacatctacc aataccagct gcgcaacgat tctgccgagt acaaggtcat
1501 tggctcctgg actgaccacc tgcaccttag aatagagcgg atgcactggc cggggagcgg
1561 gcagcagctg ccccgctcca tctgcagcct gccctgccaa ccgggtgagc ggaagaagac
1621 agtgaagggc atgccttgct gctggcactg cgagccttgc acagggtacc agtaccaggt
1681 ggaccgctac acctgtaaga cgtgtcccta tgacatgcgg cccacagaga accgcacggg
1741 ctgccggccc atccccatca tcaagcttga gtggggctcg ccctgggccg tgctgcccct
1801 cttcctggcc gtggtgggca tcgctgccac gttgttcgtg gtgatcacct ttgtgcgcta
1861 caacgacacg cccatcgtca aggcctcggg ccgtgaactg agctacgtgc tgctggcagg
1921 catcttcctg tgctatgcca ccaccttcct catgatcgct gagcccgacc ttggcacctg
1981 ctcgctgcgc cgaatcttcc tgggactagg gatgagcatc agctatgcag ccctgctcac
2041 caagaccaac cgcatctacc gcatcttcga gcagggcaag cgctcggtca gtgccccacg
2101 cttcatcagc cccgcctcac agctggccat caccttcagc ctcatctcgc tgcagctgct
2161 gggcatctgt gtgtggtttg tggtggaccc ctcccactcg gtggtggact tccaggacca
2221 gcggacactc gacccccgct tcgccagggg tgtgctcaag tgtgacatct cggacctgtc
2281 gctcatctgc ctgctgggct acagcatgct gctcatggtc acgtgcaccg tgtatgccat
2341 caagacacgc ggcgtgcccg agaccttcaa tgaggccaag cccattggct tcaccatgta
2401 caccacttgc atcgtctggc tggccttcat ccccatcttc tttggcacct cgcagtcggc
2461 cgacaagctg tacatccaga cgacgacgct gacggtctcg gtgagtctga gcgcctcggt
2521 gtccctggga atgctctaca tgcccaaagt ctacatcatc ctcttccacc cggagcagaa
2581 cgtgcccaag cgcaagcgca gcctcaaagc cgtcgttacg gcggccacca tgtccaacaa
2641 gttcacgcag aagggcaact tccggcccaa cggagaggcc aagtctgagc tctgcgagaa
2701 ccttgaggcc ccagcgctgg ccaccaaaca gacttacgtc acttacacca accatgcaat
2761 ctagcgagtc catggagctg agcagcagga ggaggagccg tgaccctgtg gaaggtgcgt
2821 cgggccaggg ccacacccaa gggcccagct gtcttgcctg cccgtgggca cccacggacg
2881 tggcttggtg ctgagatagc agagccccca gccatcactg ctggcagcct gggcaaaccg
2941 ggtgagcaac aggaggacga ggggccgggg cggtgccagg ctaccacaag aacctgcgtc
3001 ttggaccatt gcccctcccg gccccaaacc acaggggctc aggtcgtgtg ggccccagtg
3061 ctagatctct ccctcccttc gtctctgtct gtgctgttgg cgacccctct gtctgtctcc
3121 agccctgtct ttctgttctc ttatctcttt gtttcacctt ttccctctct ggcgtccccg
3181 gctgcttgta ctcttggcct tttctgtgtc tcctttctgg ctcttgcctc cgcctctctc
3241 tctcatcctc tttgtcctca gctcctcctg ctttcttggg tcccaccagt gtcacttttc
3301 tgccgttttc tttcctgttc tcctctgctt cattctcgtc cagccattgc tcccctctcc
3361 ctgccaccct tccccagttc accaaacctt acatgttgca aaagaaaaaa aaaaaaagga
3421 attcctgcag c
//