LOCUS HSU91985 1633 bp mRNA linear HUM 03-MAY-1997
DEFINITION Human DNA fragmentation factor-45 mRNA, complete cds.
ACCESSION U91985
VERSION U91985.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1633)
AUTHORS Liu,X., Zou,H., Slaughter,C. and Wang,X.
TITLE DFF, a heterodimeric protein that functions downstream of caspase-3
to trigger DNA fragmentation during apoptosis
JOURNAL Cell 89 (2), 175-184 (1997)
PUBMED 9108473
REFERENCE 2 (bases 1 to 1633)
AUTHORS Liu,X., Zou,H., Slaughter,C. and Wang,X.
TITLE Direct Submission
JOURNAL Submitted (04-MAR-1997) Biochemistry, University of Texas
Southwestern Medical Center at Dallas, 5323 Harry Hines Blvd.,
Dallas, TX 75235, USA
FEATURES Location/Qualifiers
source 1..1633
/db_xref="H-InvDB:HIT000222599"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_line="HeLa S3"
CDS 57..1052
/function="triggers DNA fragmentation during apoptosis"
/note="DFF-45"
/codon_start=1
/product="DNA fragmentation factor-45"
/protein_id="AAC51249.1"
/translation="MEVTGDAGVPESGEIRTLKPCLLRRNYSREQHGVAASCLEDLRS
KACDILAIDKSLTPVTLVLAEDGTIVDDDDYFLCLPSNTKFVALASNEKWAYNNSDGG
TAWISQESFDVDETDSGAGLKWKNVARQLKEDLSSIILLSEEDLQMLVDAPCSDLAQE
LRQSCATVQRLQHTLQQVLDQREEVRQSKQLLQLYLQALEKEGSLLSKQEESKAAFGE
EVDAVDTGISRETSSDVALASHILTALREKQAPELSLSSQDLELVTKEDPKALAVALN
WDIKKTETVQEACERELALRLQQTQSLHSLRSISASKASPPGDLQNPKRARQDPT"
BASE COUNT 413 a 432 c 451 g 337 t
ORIGIN
1 cgccgctccg gcctcccgcg acttctcgaa ggtgggcagg tcccaccttg tggaggatgg
61 aggtgaccgg ggacgccggg gtaccagaat ctggcgagat ccggactcta aagccgtgtc
121 tgctgcgccg caactacagc cgcgaacagc acggcgtggc cgcctcctgc ctcgaagacc
181 tgaggagcaa ggcctgtgac attctggcca ttgataagtc cctgacacca gtcacccttg
241 tcctggcaga ggatggcacc atagtggatg atgacgatta ctttctgtgt ctaccttcca
301 atactaagtt tgtggcattg gctagtaatg agaaatgggc atacaacaat tcagatggag
361 gtacagcttg gatttcccaa gagtcctttg atgtagatga aacagacagc ggggcagggt
421 tgaagtggaa gaatgtggcc aggcagctga aagaagatct gtccagcatc atcctcctat
481 cagaggagga cctccagatg cttgttgacg ctccctgctc agacctggct caggaactac
541 gtcagagttg tgccaccgtc cagcggctgc agcacacact ccaacaggtg cttgaccaaa
601 gagaggaagt gcgtcagtcc aagcagctcc tgcagctgta cctccaggct ttggagaaag
661 agggcagcct cttgtcaaag caggaagagt ccaaagctgc ctttggtgag gaggtggatg
721 cagtagacac gggtatcagc agagagacct cctcggacgt tgcgctggcg agccacatcc
781 ttactgcact gagggagaag caggctccag agctgagctt atctagtcag gatttggagt
841 tggttaccaa ggaagacccc aaagcactgg ctgttgcctt gaactgggac ataaagaaga
901 cggagactgt tcaggaggcc tgtgagcggg agctcgccct gcgcctgcag cagacgcaga
961 gcttgcattc tctccggagc atctcagcaa gcaaggcctc accacctggt gacctgcaga
1021 atcctaagcg agccagacag gatcccacat agcagcagcg ggaagtgtgc caaggaagct
1081 ctgtggcgtt gtgttattgg tagacaccct cagcctcatc atttgactac ctatgtacta
1141 ctctaccccc tgccttagag caccttccag agaagctatt ccaggtctca acatacgccg
1201 ttccaccaat ttttttttta gccccaccag cttcaggact tctgccaatt ttgaatgata
1261 tagctgcacc aacaatatcc cgcctcctct aattacatat gatgttctct gttcaaaagt
1321 aattggcagt gattggccag gcgcagtggc tcacgcctgt aatcccagca ctgggaggcc
1381 gaggggggcg gatcgtgaag tcaggagatc gagaccatcc tggctaacat ggtgaaaccc
1441 tgtctctact aaaaatacaa aaaaaattag ccagccatgg tggcgggcgc ctgtaatccc
1501 agctacttgg gaggctgagg caggagaatg gcatgaacct gggaggcaga gcttgcagtg
1561 agctgagatt gcgccactgc actccagcct gggcaacaga gcgagactcc gtctcaaaaa
1621 aaaaaaaaaa aaa
//