LOCUS HSU91926 1571 bp mRNA linear HUM 03-SEP-1997
DEFINITION Human clone HM43 monocyte inhibitory receptor precursor mRNA,
complete cds.
ACCESSION U91926
VERSION U91926.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1571)
AUTHORS Arm,J.P., Nwankwo,C. and Austen,K.F.
TITLE Molecular identification of a novel family of human immunoglobulin
superfamily members that possess immunoreceptor tyrosine-based
inhibitory motifs and homology to the mouse gp49B1 inhibitory
receptor
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 1571)
AUTHORS Arm,J.P.
TITLE Direct Submission
JOURNAL Submitted (04-MAR-1997) Medicine, Harvard Medical School and
Brigham and Women's Hospital, 250 Longwood Avenue, Room 628,
Boston, MA 02146, USA
FEATURES Location/Qualifiers
source 1..1571
/db_xref="H-InvDB:HIT000222590"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="19"
/map="19q13.4"
/clone="HM43"
/cell_type="monocyte"
5'UTR <1..62
CDS 63..1382
/codon_start=1
/product="monocyte inhibitory receptor precursor"
/protein_id="AAB68666.1"
/translation="MTSILTVLICLGLSLDPRTHVQAGPLPKPTLWAEPGSVITQGSP
VTLRCQGSLETQEYHLYREKKTALWITRIPQELVKKGQFPILSITWEHAGRYCCIYGS
HTAGLSESSDPLELVVTGAYSKPTLSALPSPVVTSGGNVTIQCDSQVAFDGFILCKEG
EDEHPQCLNSHSHARGSSRAIFSVGPVSPSRRWSYRCYGYDSRAPYVWSLPSDLLGLL
VPGVSKKPSLSVQPGPVVAPGEKLTFQCGSDAGYDRFVLYKEWGRDFLQRPGRQPQAG
LSQANFTLGPVSRSYGGQYTCSGAYNLSSEWSAPSDPLDILITGQIRARPFLSVRPGP
TVASGENVTLLCQSQGGMHTFLLTKEGAADSPLRLKSKRQSHKYQAEFPMSPVTSAHA
GTYRCYGSLSSNPYLLTHPSDPLELVVSGAAETLSPPQNKSDSKAGE"
sig_peptide 63..131
mat_peptide 132..1379
/product="monocyte inhibitory receptor"
3'UTR 1383..1571
regulatory 1549..1554
/regulatory_class="polyA_signal_sequence"
polyA_site 1571
/note="15 A nucleotides"
BASE COUNT 338 a 483 c 423 g 327 t
ORIGIN
1 ctctgtcctg ccagcaccga gggctcatcc atccacagag cagtgcagtg ggaggagacg
61 ccatgacctc catcctcacg gtcctgatct gtctcgggct gagcctggac cccaggaccc
121 acgtgcaggc agggcccctc cccaagccca ccctctgggc tgagccaggc tctgtgatca
181 cccaagggag tcctgtgacc ctcaggtgtc aggggagcct ggagacgcag gagtaccatc
241 tatatagaga aaagaaaaca gcactctgga ttacacggat cccacaggag cttgtgaaga
301 agggccagtt ccccatccta tccatcacct gggaacatgc agggcggtat tgctgtatct
361 atggcagcca cactgcaggc ctctcagaga gcagtgaccc cctggagctg gtggtgacag
421 gagcctacag caaacccacc ctctcagctc tgcccagccc tgtggtgacc tcaggaggga
481 atgtgaccat ccagtgtgac tcacaggtgg catttgatgg cttcattctg tgtaaggaag
541 gagaagatga acacccacaa tgcctgaact cccattccca tgcccgtggg tcatcccggg
601 ccatcttctc cgtgggcccc gtgagcccaa gtcgcaggtg gtcgtacagg tgctatggtt
661 atgactcgcg cgctccctat gtgtggtctc tacccagtga tctcctgggg ctcctggtcc
721 caggtgtttc taagaagcca tcactctcag tgcagccggg tcctgtcgtg gcccctgggg
781 agaagctgac cttccagtgt ggctctgatg ccggctacga cagatttgtt ctgtacaagg
841 agtggggacg tgacttcctc cagcgccctg gccggcagcc ccaggctggg ctctcccagg
901 ccaacttcac cctgggccct gtgagccgct cctacggggg ccagtacaca tgctccggtg
961 catacaacct ctcctccgag tggtcggccc ccagcgaccc cctggacatc ctgatcacag
1021 gacagatccg tgccagaccc ttcctctccg tgcggccggg ccccacagtg gcctcaggag
1081 agaacgtgac cctgctgtgt cagtcacagg gagggatgca cactttcctt ttgaccaagg
1141 agggggcagc tgattccccg ctgcgtctaa aatcaaagcg ccaatctcat aagtaccagg
1201 ctgaattccc catgagtcct gtgacctcgg cccacgcggg gacctacagg tgctacggct
1261 cactcagctc caacccctac ctgctgactc accccagtga ccccctggag ctcgtggtct
1321 caggagcagc tgagaccctc agcccaccac aaaacaagtc cgactccaag gctggtgagt
1381 gaggagatgc ttgccgtgat gacgctgggc acagagggtc aggtcctgtc aagaggagct
1441 gggtgtcctg ggtggacatt tgaagaatta tattcattcc aacttgaaga attattcaac
1501 acctttaaca atgtatatgt gaagtacttt attctttcat attttaaaaa taaaagataa
1561 ttatccatga a
//