LOCUS HSU91521 2609 bp mRNA linear HUM 27-OCT-1998
DEFINITION Homo sapiens peroxin 12 (PEX12) mRNA, complete cds.
ACCESSION U91521
VERSION U91521.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2609)
AUTHORS Chang,C.C., Lee,W.H., Moser,H., Valle,D. and Gould,S.J.
TITLE Isolation of the human PEX12 gene, mutated in group 3 of the
peroxisome biogenesis disorders
JOURNAL Nat. Genet. 15 (4), 385-388 (1997)
PUBMED 9090384
REFERENCE 2 (bases 1 to 2609)
AUTHORS Chang,C.-C., Lee,W.-H., Moser,H., Valle,D. and Gould,S.J.
TITLE Direct Submission
JOURNAL Submitted (27-FEB-1997) Biological Chemistry, Johns Hopkins
University School of Medicine, 725 N. Wolfe St., Baltimore, MD
21205-2185, USA
REFERENCE 3 (bases 1 to 2609)
AUTHORS Chang,C.-C., Lee,W.-H., Moser,H., Valle,D. and Gould,S.J.
TITLE Direct Submission
JOURNAL Submitted (26-OCT-1998) Biological Chemistry, Johns Hopkins
University School of Medicine, 725 N. Wolfe St., Baltimore, MD
21205-2185, USA
REMARK Sequence update by submitter
COMMENT On Oct 26, 1998 this sequence version replaced gi:1938366.
FEATURES Location/Qualifiers
source 1..2609
/db_xref="H-InvDB:HIT000222577_03"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
gene 1..2609
/gene="PEX12"
CDS 548..1627
/gene="PEX12"
/function="import of peroxisomal matrix proteins into
peroxisomes"
/note="HsPex12p"
/codon_start=1
/product="peroxin 12"
/protein_id="AAC68812.1"
/translation="MAEHGAHFTAASVADDQPSIFEVVAQDSLMTAVRPALQHVVKVL
AESNPTHYGFLWRWFDEIFTLLDLLLQQHYLSRTSASFSENFYGLKRIVMGDTHKSQR
LASAGLPKQQLWKSIMFLVLLPYLKVKLEKLVSSLREEDEYSIHPPSSRWKRFYRAFL
AAYPFVNMAWEGWFLVQQLRYILGKAQHHSPLLRLAGVQLGRLTVQDIQALEHKPAKA
SMMQQPARSVSEKINSALKKAVGGVALSLSTGLSVGVFFLQFLDWWYSSENQETIKSL
TALPTPPPPVHLDYNSDSPLLPKMKTVCPLCRKTRVNDTVLATSGYVFCYRCVFHYVR
SHQACPITGYPTEVQHLIKLYSPEN"
BASE COUNT 718 a 570 c 576 g 745 t
ORIGIN
1 cgcccgggca ggtctccctt caaacgtggc gtcgtgggtt gtttgcgcct cgcctggggt
61 cagcgagcaa ggacgggcgc gggcggggat actcaaagcc aacagctgga gtcagccctc
121 gtgtcccggg ctcacagtgg cacgactgaa tcctcagagt cggctggctt ttgagctctc
181 acgattgggg aggagggggc gtttctggtt cgcagctcca gaggattgcg ttccttcccc
241 catacctgtc ccccacagtc acgctctgcc ctgacgtgca gcatttgaca agttaccccc
301 tcgccacata ctacttccac ccacgtccga gttaactttg ttcttaacct tcttgagact
361 accctcggcc tccaggtctt tttttcccag ttcatttttg cccataagat tgagtttcga
421 gtttcagata tcatgcagaa agtttacctt taagactgag cacccatctg atactcttcc
481 tcccgaaaaa gttcatgctc acgagagagt ttgtgggaaa agtgaaagcc agtacacgca
541 ggaaactatg gctgagcacg gggctcactt cacagctgct tctgtggccg atgaccagcc
601 atccatcttt gaggtggtag cacaggacag tttaatgaca gcagtgagac ccgctcttca
661 gcatgtggtc aaggttcttg cagaatcaaa tcccacccac tatggcttct tgtggaggtg
721 gtttgatgaa atctttactc tgctagatct tctgctccag caacattatc tgtctagaac
781 cagtgcctca ttttctgaaa acttttacgg cttaaagaga attgtaatgg gggacactca
841 caagtctcag agattggcta gtgctggtct cccaaagcag cagctttgga aatctattat
901 gttcctggtt cttcttccct atctgaaagt gaagctggag aagctggttt ctagcctgag
961 agaagaggat gaatattcta ttcatccccc ttcttcccgc tggaaacgat tttacagagc
1021 tttcctggca gcctacccat ttgtgaacat ggcctgggaa ggatggtttc ttgtacaaca
1081 acttcgatac atcctaggaa aagctcagca tcactcacca ctgctgaggc tggctggagt
1141 tcagctaggt cgactgacag ttcaggatat acaagctctg gagcacaaac cagctaaggc
1201 cagcatgatg cagcaaccag ccaggagtgt tagtgagaag ataaactcag ctctgaagaa
1261 agctgttggg ggtgttgcct tatccctgtc tactggcctt tctgtgggtg tattcttctt
1321 gcagttcctt gactggtggt actcatctga aaatcaagaa accatcaagt cattgactgc
1381 cctgcctact ccaccaccac ctgtacacct agactataac tctgattctc ccctcttacc
1441 caaaatgaag actgtgtgcc cactgtgtcg taaaacccgg gtgaatgata ctgttcttgc
1501 cacctctggc tatgtgtttt gttaccgctg tgtgtttcat tatgtgagga gtcaccaagc
1561 ttgtcccatc acaggttatc caacagaagt acaacatctg attaaactct actcccctga
1621 gaactgaaag ggaatcatgt cttatcctca caacaaaagt attgcgctgt aatgtcacag
1681 agctggtttc agcatggtat tgagttgaca cttctcagcc tcaattcata actatatgaa
1741 ctttaaatga ttatatggat ttctttaaaa ggatatgccc atttgatcct aaccttttag
1801 cctgctctct agaaccctac ttacagttga ccaagctgct taaagtagaa ggatcaggac
1861 tggcagggga tatgagggcc agtgtagaga ttaaacagaa taatgagtac acaagttttt
1921 gcctatccct ttccttaaaa tataagaaat aaaggagctc ttacgaaaaa cccaggttag
1981 accgcataaa aaataaagtg aacagtgagg tggtagcaag acttcttttt agaaaagaaa
2041 gcatttacct gcctgtctgt aaggtggaaa tttcatcagt ttgcaaacga taagaaatgc
2101 agacttgctc ttgatagaaa tgcttagaaa cactctgggg gggaaaaaag ctccttccat
2161 atactgtgag acatttgtta agtgacatct attgtttatc agcttttaag gataaaaaag
2221 gtattttaaa agttggatat ttaggatatt tgaggatatt cctttatgag ctctccatat
2281 ccttcttgag aaactggtta aaaaaggaat aggggtagag tgttacagag agtagtctga
2341 agattcctgt gtaaaagcaa agctaacaag caatgaagac atgaagcaaa atactaatct
2401 aattgtgtaa agaaaggata ttttaataag ttctttctgc ttgctgctaa gagtttgcta
2461 aagtgtcatg aattattctg gttattacta aagtttctat gaaacaagta gattttaaga
2521 ataaatgttt ctggaaaagg actatgttat gattttgtag aaatgtaaag attacttgag
2581 gtgtttaaaa taaatttttc attcagact
//