LOCUS HSU89717 1230 bp mRNA linear HUM 31-DEC-1997
DEFINITION Human 9-cis-retinol specific dehydrogenase mRNA, complete cds.
ACCESSION U89717
VERSION U89717.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1230)
AUTHORS Mertz,J.R., Shang,E., Piantedosi,R., Wei,S., Wolgemuth,D.J. and
Blaner,W.S.
TITLE Identification and characterization of a stereospecific human
enzyme that catalyzes 9-cis-retinol oxidation. A possible role in
9-cis-retinoic acid formation
JOURNAL J. Biol. Chem. 272 (18), 11744-11749 (1997)
PUBMED 9115228
REFERENCE 2 (bases 1 to 1230)
AUTHORS Mertz,J.R. and Blaner,W.S.
TITLE Direct Submission
JOURNAL Submitted (15-FEB-1997) Biology, City College of New York, 138th
St. and Convent Ave., New York, NY 10031, USA
FEATURES Location/Qualifiers
source 1..1230
/db_xref="H-InvDB:HIT000222141"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="152778"
/tissue_type="breast"
/clone_lib="Soares 2NbHBst"
CDS 114..1070
/note="short chain alcohol dehydrogenase"
/codon_start=1
/product="9-cis-retinol specific dehydrogenase"
/protein_id="AAB93668.1"
/translation="MWLPLLLGALLWAVLWLLRDRQSLPASNAFVFITGCDSGFGRLL
ALQLDQKSFRVLASCLTPSGAEDLQGVASSGFNTTLLDITDPQSFQQAAKWVEMHVKE
AGLFGLVNNAGVAGIIGPTPWLTRDDFQRVLNVNTMGPIGVTLALLPLLQQARGRVIN
ITSVLGRLAANGGGYCVSKFGLEAFSDSLRRDVAHFGIRESIVEPGFFRTPVTNLESL
EKTLQACWARLPPATQAHYGGAFLTKYLKMQQRIMNLICDPDLTKVSRCLEHALTARH
PRTRYSPGWDAKLLWLPASYLPASLVDAVLTWVLPKPAQAVY"
BASE COUNT 251 a 362 c 349 g 268 t
ORIGIN
1 gagactggga gcagtctctt aaacaaaagc aaaagaataa gcttcgggcg ctgtagtacc
61 tgccagcttt cgccacagga ggctgccacc tgtaggtcac ttgggctcca gctatgtggc
121 tgcctcttct gctgggtgcc ttactctggg cagtgctgtg gttgctcagg gaccggcaga
181 gcctgcccgc cagcaatgcc tttgtcttca tcaccggctg tgactcaggc tttgggcgcc
241 ttctggcact gcagctggac cagaaaagct tccgagtcct ggccagctgc ctgaccccct
301 ccggggcgga ggacctgcag ggggtggctt cttccggctt caacaccacc ctgttggata
361 tcactgatcc ccagagcttc cagcaggcag ccaagtgggt ggagatgcac gttaaggaag
421 cagggctttt tggtctggtg aataatgctg gtgtggctgg tatcatcgga cccacaccat
481 ggctgacccg ggacgatttc cagcgggtgc tgaatgtgaa cacaatgggt cccatcgggg
541 tcacccttgc cctgctgcct ctgctgcagc aagcccgggg ccgggtgatc aacatcacca
601 gcgtcctggg tcgcctggca gccaatggtg ggggctactg tgtctccaaa tttggcctgg
661 aggccttctc tgacagcctg aggcgggatg tagctcattt tgggatacgg gagtccatcg
721 tggagcctgg tttcttccga acccctgtga ccaacttgga gagtctggag aaaaccctgc
781 aggcctgctg ggcacggctg cctcctgcca cacaggccca ctatgggggg gccttcctca
841 ccaagtacct gaaaatgcaa cagcgcatca tgaacctgat ctgtgacccg gacctaacca
901 aggtgagccg atgcctggag catgccctga ctgctcgaca cccccgaacc cgctacagcc
961 caggttggga tgccaagctg ctctggctgc ctgcctccta cctgccagcc agcctggtgg
1021 atgctgtgct cacctgggtc cttcccaagc ctgcccaagc agtctactga atccagcctt
1081 ccagcaagag attgtttttc aaggacaagg actttgattt atttctgccc ccaccctggt
1141 actgcctggt gcctgccaca aaataagcac taacaaaagt gtattgttta aaaaataaaa
1201 agaaggtggg cagaaatgtg cccagtggaa
//