LOCUS HSU89436 1683 bp mRNA linear HUM 08-DEC-1997
DEFINITION Human tyrosyl-tRNA synthetase mRNA, complete cds.
ACCESSION U89436
VERSION U89436.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1683)
AUTHORS Kleeman,T.A., Wei,D., Simpson,K.L. and First,E.A.
TITLE Human tyrosyl-tRNA synthetase shares amino acid sequence homology
with a putative cytokine
JOURNAL J. Biol. Chem. 272 (22), 14420-14425 (1997)
PUBMED 9162081
REFERENCE 2 (bases 1 to 1683)
AUTHORS First,E.A.
TITLE Direct Submission
JOURNAL Submitted (12-FEB-1997) Biochemistry and Molecular Biology,
Louisiana State University Medical Center in Shreveport, 1501 Kings
Highway, Shreveport, LA 71130, USA
FEATURES Location/Qualifiers
source 1..1683
/db_xref="H-InvDB:HIT000222134"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_type="white blood cells"
/dev_stage="adult"
CDS 1..1587
/note="class I tRNA synthetase"
/codon_start=1
/product="tyrosyl-tRNA synthetase"
/protein_id="AAB88409.1"
/translation="MGDAPSPEEKLHLITRNLQEVLGEEKLKEILKERELKIYWGTAT
TGKPHVAYFVPMSKIADFLKAGCEVTILFADLHAYLDNMKAPWELLELRVSYYENVIK
AMLESIGVPLEKLKFIKGTDYQLSKEYTLDVYRLSSVVTQHDSKKAGAEVVKQVEHPL
LSGLLYPGLQALDEEYLKVDAQFGGIDQRKIFTFAEKYLPALGYSKRVHLMNPMVPGL
TGSKMSSSEEESKIDLLDRKEDVKKKLKKAFCEPGNVENNGVLSFIKHVLFPLKSEFV
ILRDEKWGGNKTYTAYVDLEKDFAAEVVHPGDLKNSVEVALNKLLDPIREKFNTPALK
KLASAAYPDPSKQKPMAKGPAKNSEPEEVIPSRLDIRVGKIITVEKHPDADSLYVEKI
DVGEAEPRTVVSGLVQFVPKEELQDRLVVVLCNLKPQKMRGVESQGMLLCASIEGINR
QVEPLDPPAGSAPGEHVFVKGYEKGQPDEELKPKKKVFEKLQADFKISEECIAQWKQT
NFMTKLGSISCKSLKGGNIS"
misc_difference 1060^1061
/note="occurs in human tyrosyl-tRNA synthetase in GenBank
Accession Number U40714, which has an altered reading
frame downstream of this insertion"
/replace="c"
BASE COUNT 470 a 399 c 448 g 366 t
ORIGIN
1 atgggggacg ctcccagccc tgaagagaaa ctgcacctta tcacccggaa cctgcaggag
61 gttctggggg aagagaagct gaaggagata ctgaaggagc gggaacttaa aatttactgg
121 ggaacggcaa ccacgggcaa accacatgtg gcttactttg tgcccatgtc aaagattgca
181 gacttcttaa aggcagggtg tgaggtaaca attctgtttg cggacctcca cgcatacctg
241 gataacatga aagccccatg ggaacttcta gaactccgag tcagttacta tgagaatgtg
301 atcaaagcaa tgctggagag cattggtgtg cccttggaga agctcaagtt catcaaaggc
361 actgattacc agctcagcaa agagtacaca ctagatgtgt acagactctc ctccgtggtc
421 acacagcacg attccaagaa ggctggagct gaggtggtaa agcaggtgga gcaccctttg
481 ctgagtggcc tcttataccc cggactgcag gctttggatg aagagtattt aaaagtagat
541 gcccaatttg gaggcattga tcagagaaag attttcacct ttgcagagaa gtacctccct
601 gcacttggct attcaaaacg ggtccatctg atgaatccta tggttccagg attaacaggc
661 agcaaaatga gctcttcaga agaggagtcc aagattgatc tccttgatcg gaaggaggat
721 gtgaagaaaa aactgaagaa ggccttctgt gagccaggaa atgtggagaa caatggggtt
781 ctgtccttca tcaagcatgt cctttttccc cttaagtccg agtttgtgat cctacgagat
841 gagaaatggg gtggaaacaa aacctacaca gcttacgtgg acctggaaaa ggactttgct
901 gctgaggttg tacatcctgg agacctgaag aattctgttg aagtcgcact gaacaagttg
961 ctggatccaa tccgggaaaa gtttaatacc cctgccctga aaaaactggc cagcgctgcc
1021 tacccagatc cctcaaagca gaagccaatg gccaaaggcc ctgccaagaa ttcagaacca
1081 gaggaggtca tcccatcccg gctggatatc cgtgtgggga aaatcatcac tgtggagaag
1141 cacccagatg cagacagcct gtatgtagag aagattgacg tgggggaagc tgaaccacgg
1201 actgtggtga gcggcctggt acagttcgtg cccaaggagg aactgcagga caggctggta
1261 gtggtgctgt gcaacctgaa accccagaag atgagaggag tcgagtccca aggcatgctt
1321 ctgtgtgctt ctatagaagg gataaaccgc caggttgaac ctctggaccc tccggcaggc
1381 tctgctcctg gtgagcacgt gtttgtgaag ggctatgaaa agggccaacc agatgaggag
1441 ctcaagccca agaagaaagt cttcgagaag ttgcaggctg acttcaaaat ttctgaggag
1501 tgcatcgcac agtggaagca aaccaacttc atgaccaagc tgggctccat ttcctgtaaa
1561 tcgctgaaag gggggaacat tagctagcca gcccagcatc ttcccccctt cttccaccac
1621 tgagtcatct gctgtctctt cagtctgctc catccatcac ccatttaccc atctctcagg
1681 aca
//