LOCUS HSU89331 4565 bp mRNA linear HUM 03-JUN-1998
DEFINITION Human pseudoautosomal homeodomain-containing protein (PHOG) mRNA,
complete cds.
ACCESSION U89331
VERSION U89331.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4565)
AUTHORS Ellison,J.W., Wardak,Z., Young,M.F., Gehron Robey,P.,
Laig-Webster,M. and Chiong,W.
TITLE PHOG, a candidate gene for involvement in the short stature of
Turner syndrome
JOURNAL Hum. Mol. Genet. 6 (8), 1341-1347 (1997)
PUBMED 9259282
REFERENCE 2 (bases 1 to 4565)
AUTHORS Ellison,J.W., Wardak,Z., Young,M., Gehron Robey,P., Webster,M. and
Chiong,W.
TITLE Direct Submission
JOURNAL Submitted (10-FEB-1997) Pediatrics, University of California at San
Francisco, 3rd and Parnassus, San Francisco, CA 94143, USA
FEATURES Location/Qualifiers
source 1..4565
/db_xref="H-InvDB:HIT000222126_04"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="X; Y"
/map="Xp22.3; distal Yp (pseudoautosomal region)"
/cell_type="trabecular bone cell; bone marrow stromal
fibroblasts"
gene 1..4565
/gene="PHOG"
5'UTR 1..693
/gene="PHOG"
exon 1..262
/gene="PHOG"
exon 263..970
/gene="PHOG"
CDS 694..1572
/gene="PHOG"
/note="expressed at highest levels in osteogenic cells"
/codon_start=1
/product="pseudoautosomal homeodomain-containing protein"
/protein_id="AAC18820.1"
/translation="MEELTAFVSKSFDQKSKDGNGGGGGGGGKKDSITYREVLESGLA
RSRELGTSDSSLQDITEGGGHCPVHLFKDHVDNDKEKLKEFGTARVAEGIYECKEKRE
DVKSEDEDGQTKLKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEAR
VQVWFQNRRAKCRKQENQMHKGVILGTANHLDACRVAPYVNMGALRMPFQQVQAQLQL
EGVAHAHPHLHPHLAAHAPYLMFPPPPFGLPIASLAESASAAAVVAAAAKSNSKNSSI
ADLRLKARKHAEALGL"
exon 971..1179
/gene="PHOG"
misc_feature 1042..1224
/gene="PHOG"
/note="encodes homeobox"
exon 1180..1237
/gene="PHOG"
exon 1238..1326
/gene="PHOG"
exon 1327..4565
/gene="PHOG"
3'UTR 1573..4565
/gene="PHOG"
regulatory 4544..4550
/regulatory_class="polyA_signal_sequence"
/gene="PHOG"
BASE COUNT 1070 a 1214 c 1194 g 1087 t
ORIGIN
1 cgcctgcttt tgcccgggtc ctgagaacag gggctcccca cactttgttt tttttttttg
61 gttttgtttt atttcgtttc cgcgcgtctc tttctactgc aaacagaaat gggagggtgg
121 acaggcgggt aggagcggat cagacgccca ggacgcagca gcccgagtcc gcacagggtt
181 tgcgggaggt ggtgaccgcg ctggggacgc caggacgcga atgaacctcc ggggcacgct
241 cggggcctgc gctcagagct tggaaaactg gagtttcttt tcctccggcc acggagagaa
301 cgcgggtaac ctgtgtgggg ggctcgggcg cctgcgcccc cctcctgcgc gcgcgctctc
361 ccttccaaaa atgggatctt tcccccttcg caccaaggtg tacggacgcc aaacagtgat
421 gaaatgagaa gaaagccaat tgccggcctg gggggtgggg gagacacagc gtctctgcgt
481 gcgtccgccg cggagcccgg agaccagtaa ttgcaccaga caggcagcgc atggggggct
541 gggcgaggtc gccgcgtata aatagtgaga tttccaatgg aaaggcgtaa ataacagcgc
601 tggtgatcca cccgcgcgca cgggccgtcc tctccgcgcg gggagacgcg cgcatccacc
661 agccccggct gctcgccagc cccggcccca gccatggaag agctcacggc ttttgtatcc
721 aagtcttttg accagaaaag caaggacggt aacggcggag gcggaggcgg cggaggtaag
781 aaggattcca ttacgtaccg ggaagttttg gagagcggac tggcgcgctc ccgggagctg
841 gggacgtcgg attccagcct ccaggacatc acggagggcg gcggccactg cccggtgcat
901 ttgttcaagg accacgtaga caatgacaag gagaaactga aagaattcgg caccgcgaga
961 gtggcagaag ggatttatga atgcaaagag aagcgcgagg acgtgaagtc ggaggacgag
1021 gacgggcaga ccaagctgaa acagaggcgc agccgcacca acttcacgct ggagcagctg
1081 aacgagctcg agcgactctt cgacgagacc cattaccccg acgccttcat gcgcgaggag
1141 ctcagccagc gcctggggct ctccgaggcc cgcgtgcagg tttggttcca gaaccggaga
1201 gccaagtgcc gcaaacaaga gaatcagatg cataaaggcg tcatcttggg cacagccaac
1261 cacctagacg cctgccgagt ggcaccctac gtcaacatgg gagccttacg gatgcctttc
1321 caacaggtcc aggctcagct gcagctggaa ggcgtggccc acgcgcaccc gcacctgcac
1381 ccgcacctgg cggcgcacgc gccctacctg atgttccccc cgccgccctt cgggctgccc
1441 atcgcgtcgc tggccgagtc cgcctcggcc gccgccgtgg tcgccgccgc cgccaaaagc
1501 aacagcaaga attccagcat cgccgacctg cggctcaagg cgcggaagca cgcggaggcc
1561 ctggggctct gacccgccgc gcagcccccg cgcgcccgga ctcccgggct ccgcgcaccc
1621 cgcctgcacc gcgcgtcctg cactcaaccc cgcctggagc tccttccgcg gccaccgtgc
1681 tccgggcacc ccgggagctc ctgcaagagg cctgaggagg gaggctcccg gcaccgtcca
1741 cgcacgacgc agccagaccc tcgcggagat ggtgcagaag gcggagcggg tgagcggccg
1801 tgcgtccagc ccgggcctct ccaaggctgc ccgtgcgtcc tgggaccctg gagaagggta
1861 aacccccgcc tggctgcgtc ttcctctgct ataccctatg catgcggtta actacacacg
1921 tttggaagat ccttagagtc tattgaaact gcaaagatcc cggagctggt ctccggatga
1981 aaatgccatt tcttcgttgc caacgatttt ctttactacc atgctccttc cttcatcccg
2041 agaggctgcg gaacgggtgt ggatttgaat gtggacttcg gaatcccagg aggcaggggc
2101 cgggctctcc tccaccgctc ccccggagcc tcccaggcag caataaggaa atagttctct
2161 ggctgaggct gaggacgtga accgcgggct ttggaaaggg aggggaggga gacccgaacc
2221 tcccacgttg ggactcccac gttccgggga cctgaatgag gaccgacttt ataacttttc
2281 cagtgtttga ttcccaaatt gggtctggtt ttgttttgga ttggtttttt tttttttttt
2341 tttttttttt ttgctgtgtt acaggattca gacgcaaaag acttgcataa gagacggacg
2401 cgtggttgca aggtgtcata ctgatatgca gcattaactt tactgacatg gagtgaagtg
2461 caatattata aatattatag attaaaaaaa aaaatagccg tgcactcttg accccgtcaa
2521 cgtccaacgt ggaaaaggcg ttacctcttc tcccagcgct ggccgcctgg cactgagggt
2581 ccctttgcaa aaatcacggg tgtagagatg gccctgggcg cgctgggagt gtggttgtgt
2641 ttctgaaggg gataaaagag ggcacggtgg tgccaagata tcagtttggt acctgagctg
2701 tttctggttg ggaagcgtaa aagccaggga gagatccaga gagttttcaa gtttttgcag
2761 atgtaggtgg ttccagcttt tctttctccc ctactccatc ttctgcgttc ccccagttct
2821 tttatttctt tgttttttat ttttgagaca gagacttgct ttgtcgccca ggctggagcg
2881 cagtcccgca atgtcagctc accgccacct ccgccccccg ggttcaagcg atgctcctgc
2941 ctcagcctcc cgagtagctg ggactacagg cacctgccac caccaccccc gccatatttt
3001 ttgtatttat agtagagacg gcgtttcacc gtgttggcca ggctcgtctc ggaactcctg
3061 acctcaggtg atctgcccgc ctcggcctcc caacgtgccc ccagttttat aaacagcaga
3121 tagcaacttg tcgtcacagc tggcatgggc tggacagttg cttgaaatga cctaaccaaa
3181 aacattcaag ggttctgccc ccagatttcg ggagatccac gttccatgtt ctgattggtt
3241 ttctgggaac acagcaaggg gtttggtgac ctccgagaag atccatctgc atgattggca
3301 ttagttacca cagccagccc agagagaaac tatcttctcc caacatttac taacatccac
3361 tggtcaactc tcttatttcc ataacacatt tgcatctttc tggattcaag cttggtggtt
3421 ttctttccta acttctgatt tagatacttc tccctcgagg tggggataaa agaaaaaaaa
3481 aaacaacttc ttttttgctt ccgcataaca cttcctatct tgtcactgag ctgaactgta
3541 gatccatttg gacccgtctc atttgtatct tctgatattc tttatacaaa ccaaaagtcc
3601 ccttcaacat tttttatgtc aaaatgttac aaccgctgta aaatgacgga gagagagaga
3661 aagaatccca gacattaacg gtattagaga gtttgcctca ttcatccatt tttcttaaaa
3721 gctggaaatt aaaaaaaaaa aagaggagag aggctttcgg tggacacgtt tgacattaaa
3781 aaaaaaaaaa aaaaaaaaaa ctggtgccta atttattaaa gagaattagc ttagcgatgt
3841 atattctgat attcttcgac acacgtgggt aagttgatgc catttataaa tgttttattg
3901 aaatttgata tttaatgaga agccggttaa ggaatgtaga caatatcccg tttcaaagct
3961 atgaaatgtg ctatttattg aaaggggatg tggcttcacg agttcagccc attgtacgtg
4021 caggtcccgt gggaaggagg caaaagcccc tgcttcttac tttgtgatgt atgtggattt
4081 gttatttatt tttttttttc cttggtcgga cgttcataaa tatgtactat tttaattatg
4141 tcgagtgtaa atttgacatc gcgttgcatt tatttttata tttctgaaaa ctgttgcttt
4201 ttctttttcc ctcccccatt gacgacatag cggcccccgg tccgggttac aaatacatct
4261 acagatattt tcagggattg cttcagatga aaacaaatca cacaccgttt cccaaaccaa
4321 cagtcttcac atttctatcc ctctgttatt gtcggcaggc ggtgaggggt agaaaaaaaa
4381 acaaacaaac aaacaaaaaa aaaaccaaaa aaaaccaccc tgagtttctc tggtgacgcc
4441 ctcattctcc tttcgttcaa taactcaatg ttgagttgca gcaacagact gtatctttgt
4501 gacgccccgt agtatgaatg tacatcttgt aaaactgaga tataaataaa cttataaata
4561 tttgt
//