LOCUS HSU87309 4919 bp mRNA linear HUM 18-FEB-1997
DEFINITION Human hVps41p (HVPS41) mRNA, complete cds.
ACCESSION U87309
VERSION U87309.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4919)
AUTHORS Radisky,D., Snyder,W., Emr,S. and Kaplan,J.
TITLE Identification of VPS41, a gene required for vacuolar traffic and
the assembly of the yeast high affinity transport system
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 4919)
AUTHORS Radisky,D., Snyder,W., Emr,S. and Kaplan,J.
TITLE Direct Submission
JOURNAL Submitted (27-JAN-1997) Pathology, University of Utah, 50 North
Medical Drive, Salt Lake City, UT 84132, USA
FEATURES Location/Qualifiers
source 1..4919
/db_xref="H-InvDB:HIT000222022"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/tissue_type="heart"
/clone_lib="Stratagene heart cDNA library, Catalog
#936208"
gene 1..4919
/gene="HVPS41"
CDS 30..2594
/gene="HVPS41"
/function="vacuolar traffic"
/note="similar to yeast Vps41p"
/codon_start=1
/product="hVps41p"
/protein_id="AAB47563.1"
/translation="MAEAVEQETGSLEESTDESEEEESEEEPKLKYERLSNGVTEILQ
KDAASCMTVHDKFLALGTHYGKVYLLDVQGNITQKFDVSPVKINQISLDESGEHMGVC
SEDGKVQVFGLYSGEEFHETFDCPIKIIAVHPHFVRSSCKQFVTGGKKLLLFERSWMN
RWKSAVLHEGEGNIRSVKWRGHLIAWANNMGVKIFDIISKQRITNVPRDDISLRPDMY
PCSLCWKDNVTLIIGWGTSVKVCSVKERHASEMRDLPSRYVEIVSQFETEFYISGLAP
LCDQLVVLSYVKEISEKTEREYCARPRLDIIQPLSETCEEISSDALTVRGFQENECRD
YHLEYSEGESLFYIVSPRDVVVAKERDQDDHIDWLLEKKKYEEALMAAEISQKNIKRH
KILDIGLAYINHLVERGDYDIAARKCQKILGKNAALWEYEVYKFKEIGQLKAISPYLP
RGDPVLKPLIYEMILHEFLESDYEGFATLIREWPGDLYNNSVIVQAVRDHLKKDSQNK
TLLKTLAELYTYDKNYGNALEIYLTLRHKDVFQLIHKHNLFSSIKDKIVLLMDFDSEK
AVDMLLDNEDKISIKKVVEELEDRPELQHVYLHKLFKRDHHKGQRYHEKQISLYAEYD
RPNLLPFLRDSTHCPLEKALEICQQRNFVEETVYLLSRMGNSRSALKMIMEELHDVDK
AIEFAKEQDDGELWEDLILYSIDKPPFITGLLNNIGTHVDPILLIHRIKEGMEIPNLR
DSLVKILQDYNLQILLREGCKKILVADSLSLLKKMHRTQMKGVLVDEENICESCLSPI
LPSDAAKPFSVVVFHCRHMFHKECLPMPSMNSAAQFCNICSAKNRGPGSAILEMKK"
unsure 3302..4919
/gene="HVPS41"
/note="single-stranded sequence only"
repeat_region 3952..4232
/gene="HVPS41"
/rpt_family="Alu"
/rpt_type=dispersed
BASE COUNT 1485 a 928 c 1091 g 1415 t
ORIGIN
1 ttgctgtcag gtgactctcc cgtggcgcca tggcggaagc agtggagcag gaaactgggt
61 cccttgaaga atctacagat gagtctgagg aagaagagag cgaagaggaa cccaagctga
121 agtatgaaag gctttccaat ggggtaactg aaatacttca gaaggatgca gctagctgca
181 tgacagtcca tgacaagttt ttggcattgg gcacacatta tggcaaggtt tatttacttg
241 atgtccaggg gaacatcact cagaagtttg atgtaagtcc tgtgaagata aatcagatta
301 gcttggatga aagtggagag cacatgggtg tgtgttcaga ggatggcaag gtgcaggtat
361 ttggactgta ttctggagaa gaatttcacg agacttttga ctgtcccatt aaaattattg
421 ctgtgcaccc acatttcgtg agatccagtt gcaagcagtt tgtgaccgga gggaagaagc
481 tgctactgtt tgaacggtct tggatgaaca gatggaagtc tgctgttctg catgaagggg
541 aagggaacat aaggagtgtg aagtggagag gccatctgat tgcttgggcc aataatatgg
601 gtgtgaagat ttttgacatc atctcaaagc aaagaatcac caatgtgccc cgggatgata
661 taagtcttcg cccagacatg tatccctgca gcctctgctg gaaggacaat gtgacactga
721 ttattggctg ggggacttct gtcaaggtgt gctcagtgaa ggaacggcat gccagtgaaa
781 tgagggattt gccaagtcga tatgttgaaa tagtgtctca gtttgaaact gaattctaca
841 tcagtggact tgcacctctc tgtgatcagc ttgttgtact ttcgtatgta aaggagattt
901 cagaaaaaac ggaaagagaa tactgtgcca ggcctagact ggacatcatc cagccacttt
961 ctgagacttg tgaagagatc tcttctgatg ctttgacagt cagaggcttt caggagaatg
1021 aatgtagaga ttatcattta gaatactctg aaggggaatc acttttttac atcgtgagtc
1081 cgagagatgt tgtagtggcc aaggaacgag accaagatga tcacattgac tggctccttg
1141 aaaagaagaa atatgaagaa gcattgatgg cagctgaaat tagccaaaaa aatattaaaa
1201 gacataagat tctggatatt ggcttggcat atataaatca cctggtggag agaggagact
1261 atgacatagc agcacgcaaa tgccagaaaa ttcttgggaa aaatgcagca ctctgggaat
1321 atgaagttta taaatttaaa gaaattggac agcttaaggc tattagtcct tatttgccaa
1381 gaggtgatcc agttctgaaa ccactcatct atgaaatgat cttacatgaa tttttggaga
1441 gtgattatga gggttttgcc acattgatcc gagaatggcc tggagatctg tataataatt
1501 cagtcatagt tcaagcagtt cgggatcatt tgaagaaaga tagtcagaac aagactttac
1561 ttaaaaccct ggcagaattg tacacctatg acaagaacta tggcaatgct ctggaaatat
1621 acttaacatt aagacataaa gacgtttttc agttgatcca caagcataat cttttcagtt
1681 ctatcaagga taaaattgtt ttattaatgg attttgattc agagaaagct gttgacatgc
1741 ttttggacaa tgaagataaa atttcaatta aaaaggtagt ggaagaattg gaagacagac
1801 cagagctaca gcatgtgtat ttgcataagc ttttcaagag agaccaccat aaggggcagc
1861 gttaccatga aaaacagatc agtctttatg ctgaatatga tcgaccaaac ttacttccct
1921 ttctccgaga cagtacccat tgcccacttg aaaaggctct tgagatctgt caacagagaa
1981 actttgtaga agagacagtt tatcttctga gccgaatggg taatagccga agtgccctga
2041 agatgattat ggaggaatta catgatgttg ataaagcaat cgaatttgcc aaggagcaag
2101 atgatggaga gctgtgggaa gatttgattt tatattccat tgacaaacca ccatttatta
2161 ctggcttgtt aaacaacatt ggcacacatg ttgacccaat tctactgatt caccgtatta
2221 aggaaggaat ggagatcccc aatttgagag attccttggt taaaattctg caagactaca
2281 atttgcaaat tctgcttcgt gaaggctgca agaagattct cgtagctgac tctttgtcct
2341 tactgaagaa aatgcaccga actcaaatga aaggtgttct tgttgatgag gagaacatct
2401 gtgagtcgtg cctttcccct attcttccat cagatgcagc taagcccttc agcgtggtgg
2461 tcttccattg ccggcacatg ttccacaagg agtgcctgcc catgcccagc atgaactctg
2521 ctgcacagtt ctgcaacatc tgcagtgcta agaaccgtgg accaggaagt gcaattttgg
2581 agatgaaaaa atagctcatt tctccttgtc agtctccttg tcaccactct ttttgagact
2641 gtttttgcaa caacaaaagc atttgttgac actcgtgctg ttaagagatt tgtttatgtt
2701 tatattatac tcaaaaacaa tttcttcatc tattcctgta ctaatggttt ctctttgcag
2761 ttcacagaga atttggggct ctcttcatgc cttgaaattt tggggtccat agtgaatatt
2821 ttgttattta tttgtttggc tcattcttta tatagtaatg gaaacataag tctaggagtt
2881 agaaatgaat tttttagacc ttagtaaaac catttaacca taaaatggac aactgagaat
2941 tctcccagct gcctgaaagc gtcgccaact gtggttatcc tgcaagctgc tacctgcaac
3001 ttggacgttg tttccacgtg ctctgctggc tacgattctt gcattctggg tttggctttt
3061 ttctgtgtca tcaactatgg ttatcctcta aataggcatt taatgaaaca ttgtacaaat
3121 tgtcactcat ttgatgacac ctgggaataa cattagcagg ctgatgtcct gcaccattat
3181 gtttactaat cacatgttct gtgtgctgtg acgactgtca aagagtatct ggccatggcg
3241 gacactcagc atttgttgat tgaataaatg ttagctcttc tcattgtgaa ggactcactt
3301 ttactgggat aaacaaatgc agttaagaat tctggcaccc ttgtaaggaa gaaaagagag
3361 ttcaacacct tcgagtctga gcgcttgtgg ctagagtttg ccaggaggga ggaaaccagt
3421 gaccctgaaa actgagggtg cctcaggagc agtgggacca cctgatgctg aaggacggac
3481 taatgatgtt tcctcttgcc ttctctggtg cctccattgc cctccatgga acagagcata
3541 tcatagaagg agaaaaattc caacttgtaa ttgtgtctta cagttactgg cttcatcttc
3601 cttgggatat atggtcatcc tctaatgagt gtaaaagtgc gcaaaacaca tccttattgt
3661 tcctgatctc ttagtcccat aaatgggaac aaatacagct ttctgcttct ttctttttgg
3721 ggaaaggaca gggtgctagt gagtactgac agcatgccag ctaccaaagt cacccagcca
3781 ttcccatgag cagcagttca tttaattgtc acagcgtcgc caggaagaag atctgataaa
3841 cctaggttta cagataaaga aagcaaaatg tagagatgtt gttgaggtca cagaggtgac
3901 tgcctaactt cagagcaggg cttctgatcc ctttaagaaa ttacagggcc agccgggcat
3961 ggtggctcac gcccgtaatc ccagggcttt gggaagcctt ggcgggtgga tcacctgaga
4021 tcgcacgttc gagaccggcc tgaccaacat ggagaaaccc catctctact aaaaacacaa
4081 attagccagg catggtggta catgcctgta atcccggcta ctcaggaggc tgaggcagga
4141 gaatcacttg accccaggag acatatgttg tggtgagctg aggtctcgcc attgcactcc
4201 agcctgggca acaagagcaa aactccgtct caaaaaagaa aagaaaagaa aagaaatcat
4261 agggccaagt tcaaaggaaa tgcacagaac atatcttcac attagagtta agaattctct
4321 agcaaacaac agattttttt gttgttgtta gtcacaaata cttagaactg gaaggcgctt
4381 tgttattatt gaatgtaccc ctcagccttc tcagcatttc cttatcccaa gactagtgtg
4441 ctttctgcta cactgctagt tttcagtttt gttcttaccc aattgttttt tcttttcaac
4501 attaccaatt tacagattca gtttattaca tttacattaa tcctcactta tgatttgagc
4561 aagctcattt ccagaaaagt ttactttaag atcatcaata ggatttgcta atttcagtga
4621 agtcattttg cttcaggggt aaattatcct agttaccaag tcctatttgg acataaagaa
4681 aatcctactt atagaaaagg agaaaataat taaacagtct tcatttttaa gtaactgatt
4741 taaaaggaaa ataataaaat atgttcgttt atcatttcag aaattgctgt aacacactgg
4801 aaaattcctg aacaatatag attttatcgt taataaaaaa cactagcttt cgttccttag
4861 aatgtctttt cttttgaata aacagtattg ggtgatttaa aaaaaaaaaa aaaaaaaaa
//