LOCUS HSU85245 3743 bp mRNA linear HUM 19-OCT-2001
DEFINITION Human phosphatidylinositol-4-phosphate 5-kinase type II beta mRNA,
complete cds.
ACCESSION U85245
VERSION U85245.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3743)
AUTHORS Castellino,A.M., Parker,G.J., Boronenkov,I.V., Anderson,R.A. and
Chao,M.V.
TITLE A novel interaction between the juxtamembrane region of the p55
tumor necrosis factor receptor and phosphatidylinositol-4-phosphate
5-kinase
JOURNAL J. Biol. Chem. 272 (9), 5861-5870 (1997)
PUBMED 9038203
REFERENCE 2 (bases 1 to 3743)
AUTHORS Castellino,A.M., Parker,G.J., Boronenkov,I.V., Anderson,R.A. and
Chao,M.V.
TITLE Direct Submission
JOURNAL Submitted (13-JAN-1997) Pharmacology, University of
Wisconsin-Madison, 1300 University Avenue, Madison, WI 53706, USA
FEATURES Location/Qualifiers
source 1..3743
/db_xref="H-InvDB:HIT000221928"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/tissue_type="brain"
/clone_lib="Clontech #HL1149x"
/dev_stage="fetus"
CDS 481..1731
/EC_number="2.7.1.68"
/function="lipid kinase; generates phosphatidylinositol
4,5-bisphosphate from phosphatidylinositol 4-phosphate"
/note="PIP5KIIB"
/codon_start=1
/product="phosphatidylinositol-4-phosphate 5-kinase type
II beta"
/protein_id="AAB48596.1"
/translation="MSSNCTSTTAVAVAPLSASKTKTKKKHFVCQKVKLFRASEPILS
VLMWGVNHTINELSNVPVPVMLMPDDFKAYSKIKVDNHLFNKENLPSRFKFKEYCPMV
FRNLRERFGIDDQDYQNSVTRSAPINSDSQGRCGTRFLTTYDRRFVIKTVSSEDVAEM
HNILKKYHQFIVECHGNTLLPQFLGMYRLTVDGVETYMVVTRNVFSHRLTVHRKYDLK
GSTVAREASDKEKAKDLPTFKDNDFLNEGQKLHVGEESKKNFLEKLKRDVEFLAQLKI
MDYSLLVGIHDVDRAEQEEMEVEERAEDEECENDGVGGNLLCSYGTPPDSPGNLLSFP
RFFGPGEFDPSVDVYAMKSHESSPKKEVYFMAIIDILTPYDTKKKAAHAAKTVKHGAG
AEISTVNPEQYSKRFNEFMSNILT"
BASE COUNT 839 a 964 c 1095 g 845 t
ORIGIN
1 ttgcgggaaa gagccaaacc ctggcgttgg ggggcccggg cggggagccc ctcccgcggt
61 ccacagcgac gcctgcccag ccctcctccc cttccggctc cggcacgggg ccccgaggcg
121 ttcggaggcc aggcgggttt ctgtcaggcc cggggaggag gggcgggcgg ggcggccgct
181 gcctccccgg gacgggccgt accacgcgga cggggaggac ggggccaggg gactgcaggg
241 cggctgcacc gcccgggggc ggggtgcgga cgggccggcg ggctccccgg ggcggggcgg
301 gagggcgggg cgtggggcgg acggaaccac cggggcgggg tgggaggtaa cgggacgggc
361 gcgaccatgg cgcggtgagg gagcgggggt ggggatcggt ccgggggagg cctgaggccg
421 ctggcttgtg cgctgtctcc gccgcccccc tctttcgccg ccgccgccgc cgccccgggc
481 atgtcgtcca actgcaccag caccacggcg gtggcggtgg cgccgctcag cgccagcaag
541 accaagacca agaagaagca tttcgtgtgc cagaaagtga agctattccg ggccagcgag
601 ccgatcctca gcgtcctgat gtggggggtg aaccacacga tcaatgagct gagcaatgtt
661 cctgttcctg tcatgctaat gccagatgac ttcaaagcct acagcaagat caaggtggac
721 aatcatctct tcaataagga gaacctgccc agccgcttta agtttaagga gtattgcccc
781 atggtgttcc gaaaccttcg ggagaggttt ggaattgatg atcaggatta ccagaattca
841 gtgacgcgca gcgcccccat caacagtgac agccagggtc ggtgtggcac gcgtttcctc
901 accacctacg accggcgctt tgtcatcaag actgtgtcca gcgaggacgt ggcggagatg
961 cacaacatct taaagaaata ccaccagttt atagtggagt gtcatggcaa cacgcttttg
1021 ccacagttcc tgggcatgta ccgcctgacc gtggatggtg tggaaaccta catggtggtt
1081 accaggaacg tgttcagcca tcggctcact gtgcatcgca agtatgacct caagggttct
1141 acggttgcca gagaagcgag cgacaaggag aaggccaagg acttgccaac attcaaagac
1201 aatgacttcc tcaatgaagg gcagaagctg catgtgggag aggagagtaa aaagaacttc
1261 ctggagaaac tgaagcggga cgttgagttc ttggcacagc tgaagatcat ggactacagc
1321 ctgctggtgg gcatccacga cgtggaccgg gcagagcagg aggagatgga ggtggaggag
1381 cgggcagagg acgaggagtg tgagaatgat ggggtgggtg gcaacctact ctgctcctat
1441 ggcacacctc cggacagccc tggcaacctc ctcagctttc ctcggttctt tggtcctggg
1501 gaattcgacc cctctgttga cgtctatgcc atgaaaagcc atgaaagttc ccccaagaag
1561 gaggtgtatt tcatggccat cattgatatc ctcacgccat acgatacaaa gaagaaagct
1621 gcacatgctg ccaaaacggt gaaacacggg gcaggggccg agatctcgac tgtgaaccct
1681 gagcagtact ccaaacgctt caacgagttt atgtccaaca tcctgacgta gttctcttct
1741 accttcagcc gagaccgaga gactggatat ggggtcgggg atcgggactt agggagaagg
1801 gtgtatttgg gctagatggg agggtgggag cgagatcggg tttgggaggg ctttagcaat
1861 gagacttgca gcctgtgaca ccgaaagaga ctttagctga agaggagggg gatgtgctgt
1921 gtgtgcacca gctcacagga tgtaacccca ccttctgctt acccttgatt ttttctcccc
1981 atttgacacc caggttaaaa aggggttccc tttttggtac cttgtaacct tttaagatac
2041 cttggggcta gagatgactt cgtgggttta tttgggtttt gtttctgaaa tttcattgct
2101 ccaggtttgc tatttataat catatttcat cagcctaccc accctcccca tctttgctgc
2161 tctcagttcc cttcaattaa agagataccc agtagaccca gcacaagggt ccttccagaa
2221 ccaagtgcta tggatgccag attggagagg tcagacacct cgccctgctg catttgctct
2281 tgtctggatt aactttgtaa tttatggagt attgtgcaca acttcctcca cctttccctt
2341 ggattcaagt gaaaactgtt gcattattcc tccatcctgt ctggaataca ccaggtcaac
2401 accagagatc tcagatcaga atcagagatc tcagagggga ataagttcat cctcatggga
2461 tggtgagggg caggaaagcg gctgggctct tggacaccct ggttctcaga gaaccctgtg
2521 atgatcaccc aagccccagg ctgtcttagc ccctggagtt cagaagtcct ctctgtaaat
2581 cctgcctccc actaggtcaa gaggaactag agtacctttg gatttatcag gaccctcatg
2641 tttaaatggt tatttccctt tgggaaaact tcagaaactg atgtatcaaa tgaggccctg
2701 tgccctcgat ctatttcctt cttccttctg acctcctccc aggcactctt acttctagcc
2761 gaactcttag ctctgggcag atctccaagc gcctggagtg ctttttagca gagacacctc
2821 gttaagctcc gggatgacct tgtaggagat ctgtctcccc tgtgcctgga gagttacagc
2881 cagaaaggtg cccccatctt agagtgtggt gtccaaacgt gaggtggctt cctagttaca
2941 tgaggatgtg atccaggaaa tccagtttgg aggcttgatg tgggttttga cctggcctca
3001 ccttggggct gtttttcctt gttgccccgc tctagacttt tagcagatct gcacccacag
3061 gcttttttgg aaggagtggc ttcctcgagg tgttccacct gcttcggagc ctgccaccca
3121 ggccctcaga actgaccaca ggctgctctg gccaggagag aaacagctct gttgttctgc
3181 attgggggag gtacattcct gcatcttctc accccctcaa ccaggaactg gggatttggg
3241 atgagatatg gtcagacttg tagataaccc caaagatgtg aagatcgctt gtgaaaccat
3301 tttgaatgaa tagattggtt tcctgtggct ccctccaaac ctggccaagc ccagcttccg
3361 aagcaggaac cagcactgtc tctgtgcctg actcacagca tataggtcag gaaagaatgg
3421 agacggcatt cttggacttc actggggctg ctggattgga tgggaaacct tctggaagag
3481 gcagatgggg gtcaaaccac tgccttgccc caggaagggg ccataggtag gtctgaacaa
3541 ctgccggaag accactacat gacttaggga acttgaaacc aactggctca tggagaaaac
3601 aaatttgact tgggaaaggg attatgtagg aataatgttt ggacttgatt tccccacgtc
3661 ataatgaaga atggaagttt ggatctgctc ctcgtcaggc gcagcatctc tgaagcttgg
3721 aaagctgtct tccagggttg taa
//