LOCUS HSU85048 2163 bp mRNA linear HUM 24-JUL-2016
DEFINITION Homo sapiens cyclic AMP specific phosphodiesterase mRNA, partial
cds.
ACCESSION U85048
VERSION U85048.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2163)
AUTHORS Huston,E., Lumb,S., Russell,A., Catterall,C., Ross,A.H.,
Steele,M.R., Bolger,G.B., Perry,M.J., Owens,R.J. and Houslay,M.D.
TITLE Molecular cloning and transient expression in COS7 cells of a novel
human PDE4B cAMP-specific phosphodiesterase, HSPDE4B3
JOURNAL Biochem. J. 328 (Pt 2), 549-558 (1997)
PUBMED 9371714
REFERENCE 2 (bases 1 to 2163)
AUTHORS Huston,E., Lumb,S., Russell,A., Catterall,C., Perry,M.J.,
Owens,R.J. and Houslay,M.D.
TITLE Direct Submission
JOURNAL Submitted (13-JAN-1997) Biochemistry & Molecular Biology, IBLS,
University of Glasgow, Wolfson Building, University Avenue,
Glasgow, Scotland G12 8QQ, UK
FEATURES Location/Qualifiers
source 1..2163
/db_xref="H-InvDB:HIT000221905"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="1"
CDS 1..>2163
/note="splice variant PDE4B3"
/codon_start=1
/product="cyclic AMP specific phosphodiesterase"
/protein_id="AAB96381.1"
/translation="MTAKDSSKELTASEPEVCIKTFKEQMHLELELPRLPGNRPTSPK
ISPRSSPRNSPCFFRKLLVNKSIRQRRRFTVAHTCFDVENGPSPGRSPLDPQASSSAG
LVLHATFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQHGDDLIVTPFAQVLAS
LRSVRNNFTILTNLHGTSNKRSPAASQPPVSRVNPQEESYQKLAMETLEELDWCLDQL
ETIQTYRSVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSP
TQKDREKKKKQQLMTQISGVKKLMHSSSLNNTSISRFGVNTENEDHLAKELEDLNKWG
LNIFNVAGYSHNRPLTCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYHSDVAYHN
SLHAADVAQSTHVLLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSEL
ALMYNDESVLENHHLAVGFKLLQEEHCDIFMNLTKKQRQTLRKMVIDMVLATDMSKHM
SLLADLKTMVETKKVTSSGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQWTDR
IMEEFFQQGDKERERGMEISPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQ
DILDTLEDNRNWYQSMIPQSPSPPLDEQNRDCQGLMEKFQFELTLDEEDSEGPEKEGE
GHSYFSSTKTLCVIDPENRDSLGETDIDIATEDKSPVDT"
BASE COUNT 657 a 514 c 482 g 510 t
ORIGIN
1 atgacagcaa aagattcttc aaaggaactt actgcttctg aacctgaggt ttgcataaag
61 actttcaagg agcaaatgca tttagaactt gagcttccga gattaccagg aaacagacct
121 acatctccta aaatttctcc acgcagttca ccaaggaact caccatgctt tttcagaaag
181 ttactggtga ataaaagcat tcggcagcgt cgtcgcttca ctgtggctca tacatgcttt
241 gatgtggaaa atggcccttc cccaggtcgg agtccactgg atccccaggc cagctcttcc
301 gctgggctgg tacttcacgc cacctttcct gggcacagcc agcgcagaga gtcatttctc
361 tacagatcag acagcgacta tgacttgtca ccaaaggcga tgtcgagaaa ctcttctctt
421 ccaagcgagc aacacggcga tgacttgatt gtaactcctt ttgcccaggt ccttgccagc
481 ttgcgaagtg tgagaaacaa cttcactata ctgacaaacc ttcatggtac atctaacaag
541 aggtccccag ctgctagtca gcctcctgtc tccagagtca acccacaaga agaatcttat
601 caaaaattag caatggaaac gctggaggaa ttagactggt gtttagacca gctagagacc
661 atacagacct accggtctgt cagtgagatg gcttctaaca agttcaaaag aatgctgaac
721 cgggagctga cacacctctc agagatgagc cgatcaggga accaggtgtc tgaatacatt
781 tcaaatactt tcttagacaa gcagaatgat gtggagatcc catctcctac ccagaaagac
841 agggagaaaa agaaaaagca gcagctcatg acccagataa gtggagtgaa gaaattaatg
901 catagttcaa gcctaaacaa tacaagcatc tcacgctttg gagtcaacac tgaaaatgaa
961 gatcacctgg ccaaggagct ggaagacctg aacaaatggg gtcttaacat ctttaatgtg
1021 gctggatatt ctcacaatag acccctaaca tgcatcatgt atgctatatt ccaggaaaga
1081 gacctcctaa agacattcag aatctcatct gacacattta taacctacat gatgacttta
1141 gaagaccatt accattctga cgtggcatat cacaacagcc tgcacgctgc tgatgtagcc
1201 cagtcgaccc atgttctcct ttctacacca gcattagacg ctgtcttcac agatttggag
1261 atcctggctg ccatttttgc agctgccatc catgacgttg atcatcctgg agtctccaat
1321 cagtttctca tcaacacaaa ttcagaactt gctttgatgt ataatgatga atctgtgttg
1381 gaaaatcatc accttgctgt gggtttcaaa ctgctgcaag aagaacactg tgacatcttc
1441 atgaatctca ccaagaagca gcgtcagaca ctcaggaaga tggttattga catggtgtta
1501 gcaactgata tgtctaaaca tatgagcctg ctggcagacc tgaagacaat ggtagaaacg
1561 aagaaagtta caagttcagg cgttcttctc ctagacaact ataccgatcg cattcaggtc
1621 cttcgcaaca tggtacactg tgcagacctg agcaacccca ccaagtcctt ggaattgtat
1681 cggcaatgga cagaccgcat catggaggaa tttttccagc agggagacaa agagcgggag
1741 aggggaatgg aaattagccc aatgtgtgat aaacacacag cttctgtgga aaaatcccag
1801 gttggtttca tcgactacat tgtccatcca ttgtgggaga catgggcaga tttggtacag
1861 cctgatgctc aggacattct cgatacctta gaagataaca ggaactggta tcagagcatg
1921 atacctcaaa gtccctcacc accactggac gagcagaaca gggactgcca gggtctgatg
1981 gagaagtttc agtttgaact gactctcgat gaggaagatt ctgaaggacc tgagaaggag
2041 ggagagggac acagctattt cagcagcaca aagacgcttt gtgtgattga tccagaaaac
2101 agagattccc tgggagagac tgacatagac attgcaacag aagacaagtc ccccgtggat
2161 aca
//