LOCUS HSU84009 7165 bp mRNA linear HUM 04-MAR-1997
DEFINITION Human glycogen debranching enzyme isoform 3 (AGL) mRNA,
alternatively spliced isoform, complete cds.
ACCESSION U84009
VERSION U84009.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 7165)
AUTHORS Bao,Y., Dawsom,T.L. and Chen,Y.-T.
TITLE Human glycogen debranching enzyme gene (AGL): complete structural
organization and characterization of the 5' flanking region
JOURNAL Genomics 38 (1997) In press
REFERENCE 2 (bases 1 to 7165)
AUTHORS Bao,Y., Dawsom,T.L. and Chen,Y.-T.
TITLE Direct Submission
JOURNAL Submitted (07-JAN-1997) Pediatrics, Duke University Medical Center,
Box 3528, Durham, NC 27710, USA
FEATURES Location/Qualifiers
source 1..7165
/db_xref="H-InvDB:HIT000221850"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="1"
/map="1p21"
gene 1..7165
/gene="AGL"
CDS 199..4797
/gene="AGL"
/EC_number="2.4.1.25"
/note="alternatively spliced isoform"
/codon_start=1
/product="glycogen debranching enzyme isoform 3"
/protein_id="AAB48468.1"
/translation="MGHSKQIRILLLNEMEKLEKTLFRLEQGYELQFRLGPTLQGKAV
TVYTNYPFPGETFNREKFRSLDWENPTEREDDSDKYCKLNLQQSGSFQYYFLQGNEKS
GGGYIVVDPILRVGADNHVLPLDCVTLQTFLAKCLGPFDEWESRLRVAKESGYNMIHF
TPLQTLGLSRSCYSLANQLELNPDFSRPNRKYTWNDVGQLVEKLKKEWNVICITDVVY
NHTAANSKWIQEHPECAYNLVNSPHLKPAWVLDRALWRFSCDVAEGKYKEKGIPALIE
NDHHMNSIRKIIWEDIFPKLKLWEFFQVDVNKAVEQFRRLLTQENRRVTKSDPNQHLT
IIQDPEYRRFGCTVDMNIALTTFIPHDKGPAAIEECCNWFHKRMEELNSEKHRLINYH
QEQAVNCLLGNVFYERLAGHGPKLGPVTRKHPLVTRYFTFPFEEIDFSMEESMIHLPN
KACFLMAHNGWVMGDDPLRNFAEPGSEVYLRRELICWGDSVKLRYGNKPEDCPYLWAH
MKKYTEITATYFQGVRLDNCHSTPLHVAEYMLDAARNLQPNLYVVAELFTGSEDLDNV
FVTRLGISSLIREAMSAYNSHEEGRLVYRYGGEPVGSFVQPCLRPLMPAIAHALFMDI
THDNECPIVHRSAYDALPSTTIVSMACCASGSTRGYDELVPHQISVVSEERFYTKWNP
EALPSNTGEVNFQSGIIAARCAISKLHQELGAKGFIQVYVDQVDEDIVAVTRHSPSIH
QSVVAVSRTAFRNPKTSFYSKEVPQMCIPGKIEEVVLEARTIERNTKPYRKDENSING
TPDITVEIREHIQLNESKIVKQAGVATKGPNEYIQEIEFENLSPGSVIIFRVSLDPHA
QVAVGILRNHLTQFSPHFKSGSLAVDNADPILKIPFASLASRLTLAELNQILYRCESE
EKEDGGGCYDIPNWSALKYAGLQGLMSVLAEIRPKNDLGHPFCNNLRSGDWMIDYVSN
RLISRSGTIAEVGKWLQAMFFYLKQIPRYLIPCYFDAILIGAYTTLLDTAWKQMSSFV
QNGSTFVKHLSLGSVQLCGVGKFPSLPILSPALMDVPYRLNEITKEKEQCCVSLAAGL
PHFSSGIFRCWGRDTFIALRGILLITGRYVEARNIILAFAGTLRHGLIPNLLGEGIYA
RYNCRDAVWWWLQCIQDYCKMVPNGLDILKCPVSRMYPTDDSAPLPAGTLDQPLFEVI
QEAMQKHMQGIQFRERNAGPQIDRNMKDEGFNITAGVDEETGFVYGGNRFNCGTWMDK
MGESDRARNRGIPATPRDGSAVEIVGLSKSAVRWLLELSKKNIFPYHEVTVKRHGKAI
KVSYDEWNRKIQDNFEKLFHVSEDPSDLNEKHPNLVHKRGIYKDSYGASSPWCDYQLR
PNFTIAMVVAPELFTTEKAGKALEIAEKKLLGPLGMKTLDPDDMVYCGIYDNALDNDN
YNLAKGFNYHQGPEWLWPIGYFLRAKLYFSRLMGPETTAKTIVLVKNVLSRHYVHLER
SPWKGLPELTNENAQYCPFSCETQAWSIATILETLYDL"
BASE COUNT 2305 a 1205 c 1413 g 2242 t
ORIGIN
1 ctgtctacgg cagctattcc agaggcaaca actgcttccc tctgttctca tctccccatt
61 ggtggctggc gacccgaatt tgggaatggg gagattgccc acctgttatc tttgagcaga
121 ctaatctctt gggtaactca ttcgactgtg gagttctttt aattcttatg aaagatttca
181 aatcctctgg aagccaaaat gggacacagt aaacagattc gaattttact tctgaacgaa
241 atggagaaac tggaaaagac cctcttcaga cttgaacaag ggtatgagct acagttccga
301 ttaggcccaa ctttacaggg aaaagcagtt accgtgtata caaattaccc atttcctgga
361 gaaacattta atagagaaaa attccgttct ctggattggg aaaatccaac agaaagagaa
421 gatgattctg ataaatactg taaacttaat ctgcaacaat ctggttcatt tcagtattat
481 ttccttcaag gaaatgagaa aagtggtgga ggttacatag ttgtggaccc cattttacgt
541 gttggtgctg ataatcatgt gctacccttg gactgtgtta ctcttcagac atttttagct
601 aagtgtttgg gaccttttga tgaatgggaa agcagactta gggttgcaaa agaatcaggc
661 tacaacatga ttcattttac cccattgcag actcttggac tatctaggtc atgctactcc
721 cttgccaatc agttagaatt aaatcctgac ttttcaagac ctaatagaaa gtatacctgg
781 aatgatgttg gacagctagt ggaaaaatta aaaaaggaat ggaatgttat ttgtattact
841 gatgttgtct acaatcatac tgctgctaat agtaaatgga tccaggaaca tccagaatgt
901 gcctataatc ttgtgaattc tccacactta aaacctgcct gggtcttaga cagagcactt
961 tggcgtttct cctgtgatgt tgcagaaggg aaatacaaag aaaagggaat acctgctttg
1021 attgaaaatg atcaccatat gaattccatc cgaaaaataa tttgggagga tatttttcca
1081 aagcttaaac tctgggaatt tttccaagta gatgtcaaca aagcggttga gcaatttaga
1141 agacttctta cacaagaaaa taggcgagta accaagtctg atccaaacca acaccttacg
1201 attattcaag atcctgaata cagacggttt ggctgtactg tagatatgaa cattgcacta
1261 acgactttca taccacatga caaggggcca gcagcaattg aagaatgctg taattggttt
1321 cataaaagaa tggaggaatt aaattcagag aagcatcgac tcattaacta tcatcaggaa
1381 caggcagtta attgcctttt gggaaatgtg ttttatgaac gactggctgg ccatggtcca
1441 aaactaggac ctgtcactag aaagcatcct ttagttacca ggtattttac tttcccattt
1501 gaagagatag acttctccat ggaagaatct atgattcatc tgccaaataa agcttgtttt
1561 ctgatggcac acaatggatg ggtaatggga gatgatcctc ttcgaaactt tgctgaaccg
1621 ggttcagaag tttacctaag gagagaactt atttgctggg gagacagtgt taaattacgc
1681 tatgggaata aaccagagga ctgtccttat ctctgggcac acatgaaaaa atacactgaa
1741 ataactgcaa cttatttcca gggagtacgt cttgataact gccactcaac acctcttcac
1801 gtagctgagt acatgttgga tgctgctagg aatttgcaac ccaatttata tgtagtagct
1861 gaactgttca caggaagtga agatctggac aatgtctttg ttactagact gggcattagt
1921 tccttaataa gagaggcaat gagtgcatat aatagtcatg aagagggcag attagtttac
1981 cgatatggag gagaacctgt tggatccttt gttcagccct gtttgaggcc tttaatgcca
2041 gctattgcac atgccctgtt tatggatatt acgcatgata atgagtgtcc tattgtgcat
2101 agatcagcgt atgatgctct tccaagtact acaattgttt ctatggcatg ttgtgctagt
2161 ggaagtacaa gaggctatga tgaattagtg cctcatcaga tttcagtggt ttctgaagaa
2221 cggttttaca ctaagtggaa tcctgaagca ttgccttcaa acacaggtga agttaatttc
2281 caaagcggca ttattgcagc caggtgtgct atcagtaaac ttcatcagga gcttggagcc
2341 aagggtttta ttcaggtgta tgtggatcaa gttgatgaag acatagtggc agtaacaaga
2401 cactcaccta gcatccatca gtctgttgtg gctgtatcta gaactgcttt caggaatccc
2461 aagacttcat tttacagcaa ggaagtgcct caaatgtgca tccctggcaa aattgaagaa
2521 gtagttcttg aagctagaac tattgagaga aacacgaaac cttataggaa ggatgagaat
2581 tcaatcaatg gaacaccaga tatcacagta gaaattagag aacatattca gcttaatgaa
2641 agtaaaattg ttaaacaagc tggagttgcc acaaaagggc ccaatgaata tattcaagaa
2701 atagaatttg aaaacttgtc tccaggaagt gttattatat tcagagttag tcttgatcca
2761 catgcacaag tcgctgttgg aattcttcga aatcatctga cacaattcag tcctcacttt
2821 aaatctggca gcctagctgt tgacaatgca gatcctatat taaaaattcc ttttgcttct
2881 cttgcctcca gattaacttt ggctgagcta aatcagatcc tttaccgatg tgaatcagaa
2941 gaaaaggaag atggtggagg gtgctatgac ataccaaact ggtcagccct taaatatgca
3001 ggtcttcaag gtttaatgtc tgtattggca gaaataagac caaagaatga cttggggcat
3061 cctttttgta ataatttgag atctggagat tggatgattg actatgtcag taaccggctt
3121 atttcacgat caggaactat tgctgaagtt ggtaaatggt tgcaggctat gttcttctac
3181 ctgaagcaga tcccacgtta ccttatccca tgttactttg atgctatatt aattggtgca
3241 tataccactc ttctggatac agcatggaag cagatgtcaa gctttgttca gaatggttca
3301 acctttgtga aacacctttc attgggttca gttcaactgt gtggagtagg aaaattccct
3361 tccctgccaa ttctttcacc tgccctaatg gatgtacctt ataggttaaa tgagatcaca
3421 aaagaaaagg agcaatgttg tgtttctcta gctgcaggct tacctcattt ttcttctggt
3481 attttccgct gctggggaag ggatactttt attgcactta gaggtatact gctgattact
3541 ggacgctatg tagaagccag gaatattatt ttagcatttg cgggtaccct gaggcatggt
3601 ctcattccta atctactggg tgaagggatt tatgccagat acaattgtcg ggatgctgtg
3661 tggtggtggc tgcagtgtat ccaggattac tgtaaaatgg ttccaaatgg tctagacatt
3721 ctcaagtgcc cagtttccag aatgtatcct acagatgatt ctgctccttt gcctgctggc
3781 acactggatc agccattgtt tgaagtcata caggaagcaa tgcaaaaaca catgcagggc
3841 atacagttcc gagaaaggaa tgctggtccc cagatagatc gaaacatgaa ggacgaaggt
3901 tttaatataa ctgcaggagt tgatgaagaa acaggatttg tttatggagg aaatcgtttc
3961 aattgtggca catggatgga taaaatggga gaaagtgaca gagctagaaa cagaggaatc
4021 ccagccacac caagagatgg gtctgctgtg gaaattgtgg gcctgagtaa atctgctgtt
4081 cgctggttgc tggaattatc caaaaaaaat attttccctt atcatgaagt cacagtaaaa
4141 agacatggaa aggctataaa ggtctcatat gatgagtgga acagaaaaat acaagacaac
4201 tttgaaaagc tatttcatgt ttccgaagac ccttcagatt taaatgaaaa gcatccaaat
4261 ctggttcaca aacgtggcat atacaaagat agttatggag cttcaagtcc ttggtgtgac
4321 tatcagctca ggcctaattt taccatagca atggttgtgg cccctgagct ctttactaca
4381 gaaaaagcag ggaaagcttt ggagattgca gaaaaaaaat tgcttggtcc ccttggcatg
4441 aaaactttag atccagatga tatggtttac tgtggaattt atgacaatgc attagacaat
4501 gacaactaca atcttgctaa aggtttcaat tatcaccaag gacctgagtg gctgtggcct
4561 attgggtatt ttcttcgtgc aaaattatat ttttccagat tgatgggccc ggagactact
4621 gcaaagacta tagttttggt taaaaatgtt ctttcccgac attatgttca tcttgagaga
4681 tccccttgga aaggacttcc agaactgacc aatgagaatg cccagtactg tcctttcagc
4741 tgtgaaacac aagcctggtc aattgctact attcttgaga cactttatga tttatagttt
4801 attacagata ttaagtatgc aattactgta ttataggatg caaggtcatc atatgtaaat
4861 gctatatgca caggctcaag ttgttttaaa aatctcattt attataatat tgatgctcaa
4921 ttaggtaaga ttgtaaaagc attgattttt tttaatgtac agaggtagat ttcaatttga
4981 atcagaaaga aatatcatta ccaatgaaat gtgtttgagt tcagtaagaa ttattcaaat
5041 gcctagaaat ccatagtttg gaaaataaaa atcatgtcat cttctatttg tacagaaatg
5101 aaaataaaat atgaaaataa tgaaagaaat gaaaagatag cttttaattg tggtatatat
5161 aatcttcagt aacaatacat actgaatacg ctgtggttca ttaatattaa caccacgtac
5221 tatagtattc ttagaataca gtgctcactg catttaataa atatttaata aatgatgaat
5281 gatagaagtt tccatctaca atatatgttc ctaaatggag cacagatgtt caaactatgc
5341 tttcattttt tcactgatat attaattttt gtgtaatgaa tgccaacagt atattttata
5401 tgatttactt atgtgaggaa acatgcaaag cattaggaaa tttatttcct aaaaacagtt
5461 ttgtaaaatt agtattgagt tctattgagt attataagat agcttacatt ttcaaaatgg
5521 aaattgtcgg tcatatttct agaactttaa agaaaaaaga atgttatatt agttttctaa
5581 aactcaacta tctttagtca tgttcaaaaa tctattgcta gatcatagta gatactggtt
5641 ttctattaac tcaaaaccta cattgacaag tttaacattg agaagaatct taacaaaaat
5701 atggatatga attcagtaga tatcttaaat tcaataaaat cactggaagt ttttcatgat
5761 aacttatttt aagatgcctt aaaaatctta aagtcacaaa aggaaaaagg tttttaacat
5821 ttacatgagt taacattttt tcatagaact tatttcctag atagaatttt ttactgtttt
5881 ttactgtttt cttaagaaaa cagttaaatc attatgcatt cagttggaag aaagtagtgg
5941 caagaattct ttcattgcta tataatattc agtggctcat ttatacctaa taaaataatg
6001 gtattttaaa ataatgctac tttcaaagta gcattttttt agttagttta caggttacat
6061 acccaaaacc ttaactatga ctaagaaatt aaagaagaaa accagcaaac taaaacttct
6121 gggcagcaaa aatatataaa tgcttcagat gtcaaatacc catgcttgaa agctcgtgta
6181 atttacttta agattatctg cctgctcttc ttcaaagctg accttgcttt agaaatagtt
6241 ttaactagct tagttttctg gtttccaaaa ctaaaataga ttaaatccta caaatttaag
6301 gacagttgtg acagtaatct gaccactatc tataaataca ttggacattg gtttccaaat
6361 ctccctttct cttcagttcc ttccttgttc aatatatacc cttctctaaa ctgtgcgggt
6421 aaaaggaatg actgtccttg agagaaccat tagtttatca aaggtttatg tagttttgtt
6481 gctgtaccct aactttgata ttcagggagg taggaaaggt aacagaaaac cagcatattt
6541 aatcaaagca agaagtaatc gctgacagtt aaatgtgacc aaaaaaatta aaagttcaca
6601 atttttttaa tgtagccatt tggggttatc tctagtaagg cagataccca cgttggtaaa
6661 tttttaggat attgtgttgc actagaaaac taagtggttc atatttctaa tgaggaagat
6721 taatgaaaga acattgttat attctgcgtg gtatatttta aagtttaaga aggcatgtta
6781 aacattattt cctctatggt agttaaaata cagaattaga tttttaacag gtgtcatttg
6841 actaaacgtt tcggtagaat gcttcatact tgagtgatgc tggataaggt attgtatttc
6901 aacaatggac tatgccttgg tttttcacta atcaaaatca aaattactct ttaacatgat
6961 aaatgaattt accagtttag tatgctgtgg tattttaata agttttcaaa gataattggg
7021 aaaacatgag actggtcata ttgatgaata ttgtaacatg tgaattgtga tccatttctg
7081 atatgtcttg aactactgtg tctagtaggc aaatgtcatt gttacctctg tgtgttaaga
7141 aaataaaaat attttctaaa ggtcg
//