LOCUS HSU84007 7367 bp mRNA linear HUM 07-AUG-2009
DEFINITION Human glycogen debranching enzyme isoform 1 (AGL) mRNA,
alternatively spliced isoform, complete cds.
ACCESSION U84007
VERSION U84007.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 7367)
AUTHORS Bao,Y., Dawson,T.L. Jr. and Chen,Y.T.
TITLE Human glycogen debranching enzyme gene (AGL): complete structural
organization and characterization of the 5' flanking region
JOURNAL Genomics 38 (2), 155-165 (1996)
PUBMED 8954797
REFERENCE 2 (bases 1 to 7367)
AUTHORS Bao,Y., Dawsom,T.L. and Chen,Y.-T.
TITLE Direct Submission
JOURNAL Submitted (07-JAN-1997) Pediatrics, Duke University Medical Center,
Box 3528, Durham, NC 27710, USA
FEATURES Location/Qualifiers
source 1..7367
/db_xref="H-InvDB:HIT000221848"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="1"
/map="1p21"
gene 1..7367
/gene="AGL"
CDS 401..4999
/gene="AGL"
/EC_number="2.4.1.25"
/note="alternatively spliced isoform"
/codon_start=1
/product="glycogen debranching enzyme isoform 1"
/protein_id="AAB48466.1"
/translation="MGHSKQIRILLLNEMEKLEKTLFRLEQGYELQFRLGPTLQGKAV
TVYTNYPFPGETFNREKFRSLDWENPTEREDDSDKYCKLNLQQSGSFQYYFLQGNEKS
GGGYIVVDPILRVGADNHVLPLDCVTLQTFLAKCLGPFDEWESRLRVAKESGYNMIHF
TPLQTLGLSRSCYSLANQLELNPDFSRPNRKYTWNDVGQLVEKLKKEWNVICITDVVY
NHTAANSKWIQEHPECAYNLVNSPHLKPAWVLDRALWRFSCDVAEGKYKEKGIPALIE
NDHHMNSIRKIIWEDIFPKLKLWEFFQVDVNKAVEQFRRLLTQENRRVTKSDPNQHLT
IIQDPEYRRFGCTVDMNIALTTFIPHDKGPAAIEECCNWFHKRMEELNSEKHRLINYH
QEQAVNCLLGNVFYERLAGHGPKLGPVTRKHPLVTRYFTFPFEEIDFSMEESMIHLPN
KACFLMAHNGWVMGDDPLRNFAEPGSEVYLRRELICWGDSVKLRYGNKPEDCPYLWAH
MKKYTEITATYFQGVRLDNCHSTPLHVAEYMLDAARNLQPNLYVVAELFTGSEDLDNV
FVTRLGISSLIREAMSAYNSHEEGRLVYRYGGEPVGSFVQPCLRPLMPAIAHALFMDI
THDNECPIVHRSAYDALPSTTIVSMACCASGSTRGYDELVPHQISVVSEERFYTKWNP
EALPSNTGEVNFQSGIIAARCAISKLHQELGAKGFIQVYVDQVDEDIVAVTRHSPSIH
QSVVAVSRTAFRNPKTSFYSKEVPQMCIPGKIEEVVLEARTIERNTKPYRKDENSING
TPDITVEIREHIQLNESKIVKQAGVATKGPNEYIQEIEFENLSPGSVIIFRVSLDPHA
QVAVGILRNHLTQFSPHFKSGSLAVDNADPILKIPFASLASRLTLAELNQILYRCESE
EKEDGGGCYDIPNWSALKYAGLQGLMSVLAEIRPKNDLGHPFCNNLRSGDWMIDYVSN
RLISRSGTIAEVGKWLQAMFFYLKQIPRYLIPCYFDAILIGAYTTLLDTAWKQMSSFV
QNGSTFVKHLSLGSVQLCGVGKFPSLPILSPALMDVPYRLNEITKEKEQCCVSLAAGL
PHFSSGIFRCWGRDTFIALRGILLITGRYVEARNIILAFAGTLRHGLIPNLLGEGIYA
RYNCRDAVWWWLQCIQDYCKMVPNGLDILKCPVSRMYPTDDSAPLPAGTLDQPLFEVI
QEAMQKHMQGIQFRERNAGPQIDRNMKDEGFNITAGVDEETGFVYGGNRFNCGTWMDK
MGESDRARNRGIPATPRDGSAVEIVGLSKSAVRWLLELSKKNIFPYHEVTVKRHGKAI
KVSYDEWNRKIQDNFEKLFHVSEDPSDLNEKHPNLVHKRGIYKDSYGASSPWCDYQLR
PNFTIAMVVAPELFTTEKAGKALEIAEKKLLGPLGMKTLDPDDMVYCGIYDNALDNDN
YNLAKGFNYHQGPEWLWPIGYFLRAKLYFSRLMGPETTAKTIVLVKNVLSRHYVHLER
SPWKGLPELTNENAQYCPFSCETQAWSIATILETLYDL"
BASE COUNT 2317 a 1305 c 1483 g 2262 t
ORIGIN
1 cccggaagtg ggccagaggt acggtccgct cccacctggg gcgagtgcgc gcacggccag
61 gttgggtacc gggtgcgccc aggaacccgc gcgaggcgaa gtcgctgaga ctctgcctgc
121 ttctcaccca gctgcctcgg cgctgccccg gtcgctcgcc gcccctccct ttgcccttca
181 cggcgcccgg ccctccttgg gctgcggctt ctgtgcgagg ctgggcagcc agcccttccc
241 cttctgtttc tccccgtccc ctccccccga ccgtagcacc agagtcgcgg gtcctgcagt
301 gccccagaag ccgcacgtat aactccctcg gcgggtaact cattcgactg tggagttctt
361 ttaattctta tgaaagattt caaatcctct ggaagccaaa atgggacaca gtaaacagat
421 tcgaatttta cttctgaacg aaatggagaa actggaaaag accctcttca gacttgaaca
481 agggtatgag ctacagttcc gattaggccc aactttacag ggaaaagcag ttaccgtgta
541 tacaaattac ccatttcctg gagaaacatt taatagagaa aaattccgtt ctctggattg
601 ggaaaatcca acagaaagag aagatgattc tgataaatac tgtaaactta atctgcaaca
661 atctggttca tttcagtatt atttccttca aggaaatgag aaaagtggtg gaggttacat
721 agttgtggac cccattttac gtgttggtgc tgataatcat gtgctaccct tggactgtgt
781 tactcttcag acatttttag ctaagtgttt gggacctttt gatgaatggg aaagcagact
841 tagggttgca aaagaatcag gctacaacat gattcatttt accccattgc agactcttgg
901 actatctagg tcatgctact cccttgccaa tcagttagaa ttaaatcctg acttttcaag
961 acctaataga aagtatacct ggaatgatgt tggacagcta gtggaaaaat taaaaaagga
1021 atggaatgtt atttgtatta ctgatgttgt ctacaatcat actgctgcta atagtaaatg
1081 gatccaggaa catccagaat gtgcctataa tcttgtgaat tctccacact taaaacctgc
1141 ctgggtctta gacagagcac tttggcgttt ctcctgtgat gttgcagaag ggaaatacaa
1201 agaaaaggga atacctgctt tgattgaaaa tgatcaccat atgaattcca tccgaaaaat
1261 aatttgggag gatatttttc caaagcttaa actctgggaa tttttccaag tagatgtcaa
1321 caaagcggtt gagcaattta gaagacttct tacacaagaa aataggcgag taaccaagtc
1381 tgatccaaac caacacctta cgattattca agatcctgaa tacagacggt ttggctgtac
1441 tgtagatatg aacattgcac taacgacttt cataccacat gacaaggggc cagcagcaat
1501 tgaagaatgc tgtaattggt ttcataaaag aatggaggaa ttaaattcag agaagcatcg
1561 actcattaac tatcatcagg aacaggcagt taattgcctt ttgggaaatg tgttttatga
1621 acgactggct ggccatggtc caaaactagg acctgtcact agaaagcatc ctttagttac
1681 caggtatttt actttcccat ttgaagagat agacttctcc atggaagaat ctatgattca
1741 tctgccaaat aaagcttgtt ttctgatggc acacaatgga tgggtaatgg gagatgatcc
1801 tcttcgaaac tttgctgaac cgggttcaga agtttaccta aggagagaac ttatttgctg
1861 gggagacagt gttaaattac gctatgggaa taaaccagag gactgtcctt atctctgggc
1921 acacatgaaa aaatacactg aaataactgc aacttatttc cagggagtac gtcttgataa
1981 ctgccactca acacctcttc acgtagctga gtacatgttg gatgctgcta ggaatttgca
2041 acccaattta tatgtagtag ctgaactgtt cacaggaagt gaagatctgg acaatgtctt
2101 tgttactaga ctgggcatta gttccttaat aagagaggca atgagtgcat ataatagtca
2161 tgaagagggc agattagttt accgatatgg aggagaacct gttggatcct ttgttcagcc
2221 ctgtttgagg cctttaatgc cagctattgc acatgccctg tttatggata ttacgcatga
2281 taatgagtgt cctattgtgc atagatcagc gtatgatgct cttccaagta ctacaattgt
2341 ttctatggca tgttgtgcta gtggaagtac aagaggctat gatgaattag tgcctcatca
2401 gatttcagtg gtttctgaag aacggtttta cactaagtgg aatcctgaag cattgccttc
2461 aaacacaggt gaagttaatt tccaaagcgg cattattgca gccaggtgtg ctatcagtaa
2521 acttcatcag gagcttggag ccaagggttt tattcaggtg tatgtggatc aagttgatga
2581 agacatagtg gcagtaacaa gacactcacc tagcatccat cagtctgttg tggctgtatc
2641 tagaactgct ttcaggaatc ccaagacttc attttacagc aaggaagtgc ctcaaatgtg
2701 catccctggc aaaattgaag aagtagttct tgaagctaga actattgaga gaaacacgaa
2761 accttatagg aaggatgaga attcaatcaa tggaacacca gatatcacag tagaaattag
2821 agaacatatt cagcttaatg aaagtaaaat tgttaaacaa gctggagttg ccacaaaagg
2881 gcccaatgaa tatattcaag aaatagaatt tgaaaacttg tctccaggaa gtgttattat
2941 attcagagtt agtcttgatc cacatgcaca agtcgctgtt ggaattcttc gaaatcatct
3001 gacacaattc agtcctcact ttaaatctgg cagcctagct gttgacaatg cagatcctat
3061 attaaaaatt ccttttgctt ctcttgcctc cagattaact ttggctgagc taaatcagat
3121 cctttaccga tgtgaatcag aagaaaagga agatggtgga gggtgctatg acataccaaa
3181 ctggtcagcc cttaaatatg caggtcttca aggtttaatg tctgtattgg cagaaataag
3241 accaaagaat gacttggggc atcctttttg taataatttg agatctggag attggatgat
3301 tgactatgtc agtaaccggc ttatttcacg atcaggaact attgctgaag ttggtaaatg
3361 gttgcaggct atgttcttct acctgaagca gatcccacgt taccttatcc catgttactt
3421 tgatgctata ttaattggtg catataccac tcttctggat acagcatgga agcagatgtc
3481 aagctttgtt cagaatggtt caacctttgt gaaacacctt tcattgggtt cagttcaact
3541 gtgtggagta ggaaaattcc cttccctgcc aattctttca cctgccctaa tggatgtacc
3601 ttataggtta aatgagatca caaaagaaaa ggagcaatgt tgtgtttctc tagctgcagg
3661 cttacctcat ttttcttctg gtattttccg ctgctgggga agggatactt ttattgcact
3721 tagaggtata ctgctgatta ctggacgcta tgtagaagcc aggaatatta ttttagcatt
3781 tgcgggtacc ctgaggcatg gtctcattcc taatctactg ggtgaaggga tttatgccag
3841 atacaattgt cgggatgctg tgtggtggtg gctgcagtgt atccaggatt actgtaaaat
3901 ggttccaaat ggtctagaca ttctcaagtg cccagtttcc agaatgtatc ctacagatga
3961 ttctgctcct ttgcctgctg gcacactgga tcagccattg tttgaagtca tacaggaagc
4021 aatgcaaaaa cacatgcagg gcatacagtt ccgagaaagg aatgctggtc cccagataga
4081 tcgaaacatg aaggacgaag gttttaatat aactgcagga gttgatgaag aaacaggatt
4141 tgtttatgga ggaaatcgtt tcaattgtgg cacatggatg gataaaatgg gagaaagtga
4201 cagagctaga aacagaggaa tcccagccac accaagagat gggtctgctg tggaaattgt
4261 gggcctgagt aaatctgctg ttcgctggtt gctggaatta tccaaaaaaa atattttccc
4321 ttatcatgaa gtcacagtaa aaagacatgg aaaggctata aaggtctcat atgatgagtg
4381 gaacagaaaa atacaagaca actttgaaaa gctatttcat gtttccgaag acccttcaga
4441 tttaaatgaa aagcatccaa atctggttca caaacgtggc atatacaaag atagttatgg
4501 agcttcaagt ccttggtgtg actatcagct caggcctaat tttaccatag caatggttgt
4561 ggcccctgag ctctttacta cagaaaaagc agggaaagct ttggagattg cagaaaaaaa
4621 attgcttggt ccccttggca tgaaaacttt agatccagat gatatggttt actgtggaat
4681 ttatgacaat gcattagaca atgacaacta caatcttgct aaaggtttca attatcacca
4741 aggacctgag tggctgtggc ctattgggta ttttcttcgt gcaaaattat atttttccag
4801 attgatgggc ccggagacta ctgcaaagac tatagttttg gttaaaaatg ttctttcccg
4861 acattatgtt catcttgaga gatccccttg gaaaggactt ccagaactga ccaatgagaa
4921 tgcccagtac tgtcctttca gctgtgaaac acaagcctgg tcaattgcta ctattcttga
4981 gacactttat gatttatagt ttattacaga tattaagtat gcaattactg tattatagga
5041 tgcaaggtca tcatatgtaa atgctatatg cacaggctca agttgtttta aaaatctcat
5101 ttattataat attgatgctc aattaggtaa gattgtaaaa gcattgattt tttttaatgt
5161 acagaggtag atttcaattt gaatcagaaa gaaatatcat taccaatgaa atgtgtttga
5221 gttcagtaag aattattcaa atgcctagaa atccatagtt tggaaaataa aaatcatgtc
5281 atcttctatt tgtacagaaa tgaaaataaa atatgaaaat aatgaaagaa atgaaaagat
5341 agcttttaat tgtggtatat ataatcttca gtaacaatac atactgaata cgctgtggtt
5401 cattaatatt aacaccacgt actatagtat tcttagaata cagtgctcac tgcatttaat
5461 aaatatttaa taaatgatga atgatagaag tttccatcta caatatatgt tcctaaatgg
5521 agcacagatg ttcaaactat gctttcattt tttcactgat atattaattt ttgtgtaatg
5581 aatgccaaca gtatatttta tatgatttac ttatgtgagg aaacatgcaa agcattagga
5641 aatttatttc ctaaaaacag ttttgtaaaa ttagtattga gttctattga gtattataag
5701 atagcttaca ttttcaaaat ggaaattgtc ggtcatattt ctagaacttt aaagaaaaaa
5761 gaatgttata ttagttttct aaaactcaac tatctttagt catgttcaaa aatctattgc
5821 tagatcatag tagatactgg ttttctatta actcaaaacc tacattgaca agtttaacat
5881 tgagaagaat cttaacaaaa atatggatat gaattcagta gatatcttaa attcaataaa
5941 atcactggaa gtttttcatg ataacttatt ttaagatgcc ttaaaaatct taaagtcaca
6001 aaaggaaaaa ggtttttaac atttacatga gttaacattt tttcatagaa cttatttcct
6061 agatagaatt ttttactgtt ttttactgtt ttcttaagaa aacagttaaa tcattatgca
6121 ttcagttgga agaaagtagt ggcaagaatt ctttcattgc tatataatat tcagtggctc
6181 atttatacct aataaaataa tggtatttta aaataatgct actttcaaag tagcattttt
6241 ttagttagtt tacaggttac atacccaaaa ccttaactat gactaagaaa ttaaagaaga
6301 aaaccagcaa actaaaactt ctgggcagca aaaatatata aatgcttcag atgtcaaata
6361 cccatgcttg aaagctcgtg taatttactt taagattatc tgcctgctct tcttcaaagc
6421 tgaccttgct ttagaaatag ttttaactag cttagttttc tggtttccaa aactaaaata
6481 gattaaatcc tacaaattta aggacagttg tgacagtaat ctgaccacta tctataaata
6541 cattggacat tggtttccaa atctcccttt ctcttcagtt ccttccttgt tcaatatata
6601 cccttctcta aactgtgcgg gtaaaaggaa tgactgtcct tgagagaacc attagtttat
6661 caaaggttta tgtagttttg ttgctgtacc ctaactttga tattcaggga ggtaggaaag
6721 gtaacagaaa accagcatat ttaatcaaag caagaagtaa tcgctgacag ttaaatgtga
6781 ccaaaaaaat taaaagttca caattttttt aatgtagcca tttggggtta tctctagtaa
6841 ggcagatacc cacgttggta aatttttagg atattgtgtt gcactagaaa actaagtggt
6901 tcatatttct aatgaggaag attaatgaaa gaacattgtt atattctgcg tggtatattt
6961 taaagtttaa gaaggcatgt taaacattat ttcctctatg gtagttaaaa tacagaatta
7021 gatttttaac aggtgtcatt tgactaaacg tttcggtaga atgcttcata cttgagtgat
7081 gctggataag gtattgtatt tcaacaatgg actatgcctt ggtttttcac taatcaaaat
7141 caaaattact ctttaacatg ataaatgaat ttaccagttt agtatgctgt ggtattttaa
7201 taagttttca aagataattg ggaaaacatg agactggtca tattgatgaa tattgtaaca
7261 tgtgaattgt gatccatttc tgatatgtct tgaactactg tgtctagtag gcaaatgtca
7321 ttgttacctc tgtgtgttaa gaaaataaaa atattttcta aaggtcg
//