LOCUS HSU83460 1804 bp mRNA linear HUM 09-AUG-1997
DEFINITION Human high-affinity copper uptake protein (hCTR1) mRNA, complete
cds.
ACCESSION U83460
VERSION U83460.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1804)
AUTHORS Zhou,B. and Gitschier,J.
TITLE hCTR1: a human gene for copper uptake identified by complementation
in yeast
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 94 (14), 7481-7486 (1997)
PUBMED 9207117
REFERENCE 2 (bases 1 to 1804)
AUTHORS Zhou,B. and Gitschier,J.M.
TITLE Direct Submission
JOURNAL Submitted (31-DEC-1996) Howard Hughes Medical Institute, 513
Parnassus, San Francisco, CA 94143, USA
FEATURES Location/Qualifiers
source 1..1804
/db_xref="H-InvDB:HIT000221825"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="9"
/map="9q31-q32"
gene 1..1804
/gene="hCTR1"
CDS 153..725
/gene="hCTR1"
/note="contains 3 putative transmembrane domains; similar
to copper transporters found in Arabidopsis thaliana,
COPT1, and in Saccharomyces cerevisae, CTR1"
/codon_start=1
/product="high-affinity copper uptake protein"
/protein_id="AAB66306.1"
/translation="MDHSHHMGMSYMDSNSTMQPSHHHPTTSASHSHGGGDSSMMMMP
MTFYFGFKNVELLFSGLVINTAGEMAGAFVAVFLLAMFYEGLKIARESLLRKSQVSIR
YNSMPVPGPNGTILMETHKTVGQQMLSFPHLLQTVLHIIQVVISYFLMLIFMTYNGYL
CIAVAAGAGTGYFLFSWKKAVVVDITEHCH"
BASE COUNT 500 a 411 c 423 g 470 t
ORIGIN
1 gcggtggtgg acacgtcgag ccgggtagaa gtggaggggc cgttcgaaga gtcgtgaggg
61 ggtgacgggt taagattcgg agagagaggt gctagtggct ggacttgacc tggaaagaat
121 cttctgctga ctctcaactt ttcctggaaa aaatggatca ttcccaccat atggggatga
181 gctatatgga ctccaacagt accatgcaac cttctcacca tcacccaacc acttcagcct
241 cacactccca tggtggagga gacagcagca tgatgatgat gcctatgacc ttctactttg
301 gctttaagaa tgtggaacta ctgttttccg gtttggtgat caatacagct ggagaaatgg
361 ctggagcttt tgtggcagtg tttttactag caatgttcta tgaaggactc aagatagccc
421 gagagagcct gctgcgtaag tcacaagtca gcattcgcta caattccatg cctgtcccag
481 gaccaaatgg aaccatcctt atggagacac acaaaactgt tgggcaacag atgctgagct
541 ttcctcacct cctgcaaaca gtgctgcaca tcatccaggt ggtcataagc tacttcctca
601 tgctcatctt catgacctac aacgggtacc tctgcattgc agtagcagca ggggccggta
661 caggatactt cctcttcagc tggaagaagg cagtggtagt ggatatcaca gagcattgcc
721 attgacatca aactctatgg cgtggcctta tcgattgcag tgggaagttg ttgaagactt
781 gaagacgtga ttcctgctcc aatcatccct tcttgctcct ctttgtgcac gtacacacac
841 acacacacac acacacacac acacacaccc ctgctcaaca gaggtttagt ttacagtctc
901 tgaactaaag tagtaacctc ccaaattgtt ttttctaata agctgagatt cccatttctc
961 ttaaggagaa gccacccatg agatgtcttt tccttctcca tcatcttaga gccaagttat
1021 atgttcttgt ctaatccatg tagctttttg ttcaatgact tgatcatctg cttccttttt
1081 gaatttttaa cagatagtaa gtaaatttgg tggttttttc ccctgggtca gtgatggaaa
1141 ggggttaact tcagccagga ttgatggcag ctgagggaaa ttcttgccca actaaaccca
1201 gaactcaaac ttaacattag aaaataaggt ccagggccgg acacagtggc ccatgcctgt
1261 aatcccagca ctttgggggg ccaaggcagg ctggatcacc tgaggacagg agttcgagac
1321 cagtctggcc aacatgggga aaccccgtct ctactaaaaa tacaaaaatt agccgggcat
1381 ggtggtgggc gcctgtaatc ccagctactc agaaggctga ggcaggagaa tcacttgaac
1441 ctaggaggcg gaggttgcag tgagccaaga tggcgccatt gcactccagc ctgggtgaca
1501 agagtgaaac tccatctcaa aaaaaaagaa aagaaggtcc agcttttgga ttcaatgagt
1561 gggaaataca ttgtgccttt ctctagatgt gatacgttat accaaaatct ttgtagtgtg
1621 cagagcggtg gtttgagact aaatacaggc ttagaacttg cagagtgtgt attcttggat
1681 ggctgatgca tcgacttgca ttcccactta acactttgat tagccatgaa cttgccaatc
1741 aaaaaatgac aatcaatttg agaaaataga aatagatatt tttaaataaa accattcaca
1801 gttt
//