LOCUS HSU83246 1985 bp mRNA linear HUM 08-MAY-1998
DEFINITION Homo sapiens copine I mRNA, complete cds.
ACCESSION U83246
VERSION U83246.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1985)
AUTHORS Creutz,C.E., Tomsig,J.L., Snyder,S.L., Gautier,M.C., Skouri,F.,
Beisson,J. and Cohen,J.
TITLE The copines, a novel class of C2 domain-containing,
calcium-dependent, phospholipid-binding proteins conserved from
Paramecium to humans
JOURNAL J. Biol. Chem. 273 (3), 1393-1402 (1998)
PUBMED 9430674
REFERENCE 2 (bases 1 to 1985)
AUTHORS Tomsig,J.L. and Creutz,C.E.
TITLE Direct Submission
JOURNAL Submitted (26-DEC-1996) Pharmacology, University of Virginia, 1300
Jefferson Park Ave., Charlottesville, VA 22908, USA
FEATURES Location/Qualifiers
source 1..1985
/db_xref="H-InvDB:HIT000221820"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
CDS 157..1770
/function="membrane-binding protein"
/note="contains two C2-domains; calcium-dependent"
/codon_start=1
/product="copine I"
/protein_id="AAC15920.1"
/translation="MAHCVTLVQLSISCDHLIDKDIGSKSDPLCVLLQDVGGGSWAEL
GRTERVRNCSSPEFSKTLQLEYRFETVQKLRFGIYDIDNKTPELRDDDFLGGAECSLG
QIVSSQVLTLPLMLKPGKPAGRGTITVSAQELKDNRVVTMEVEARNLDKKDFLGKSDP
FLEFFRQGDGKWHLVYRSEVIKNNLNPTWKRFSVPVQHFCGGNPSTPIQVQCSDYDSD
GSHDLIGTFHTSLAQLQAVPAEFECIHPEKQQKKKSYKNSGTIRVKICRVETEYSFLD
YVMGGCQINFTVGVDFTGSNGDPSSPDSLHYLSPTGVNEYLMALWSVGSVVQDYDSDK
LFPAFGFGAQVPPDWQVSHEFALNFNPSNPYCAGIQGIVDAYRQALPQVRLYGPTNFA
PIINHVARFAAQAAHQGTASQYFMLLLLTDGAVTDVEATREAVVRASNLPMSVIIVGV
GGADFEAMEQLDADGGPLHTRSGQAAARDIVQFVPYRRFQNAPREALAQTVLAEVPTQ
LVSYFRAQGWAPLKPLPPSAKDPAQAPQA"
BASE COUNT 465 a 538 c 511 g 470 t
ORIGIN
1 accaggcaaa tattccattc agcattacaa agatggatgt tcttcagttc ctagaaggaa
61 tcccagtgga tgaaaatgct gtacatgttc ttgttgataa caatgggcaa ggtctaggac
121 aggcattggt tcagtttaaa aatgaagatg atgcacatgg cccactgcgt gaccttggtt
181 cagctgtcca tttcctgtga ccatctcatt gacaaggaca tcggctccaa gtctgaccca
241 ctctgcgtcc ttttacagga tgtgggaggg ggcagctggg ctgagcttgg ccggactgaa
301 cgggtgcgga actgctcaag ccctgagttc tccaagactc tacagcttga gtaccgcttt
361 gagacagtcc agaagctacg ctttggaatc tatgacatag acaacaagac gccagagctg
421 agggatgatg acttcctagg gggtgctgag tgttccctag gacagattgt gtccagccag
481 gtactgactc tccccttgat gctgaagcct ggaaaacctg ctgggcgggg gaccatcacg
541 gtctcagctc aggaattaaa ggacaatcgt gtagtaacca tggaggtaga ggccagaaac
601 ctagataaga aggacttcct gggaaaatca gatccatttc tggagttctt ccgccagggt
661 gatgggaaat ggcacctggt gtacagatct gaggtcatca agaacaacct gaaccctaca
721 tggaagcgtt tctcagtccc cgttcagcat ttctgtggtg ggaaccccag cacacccatc
781 caggtgcaat gctccgatta tgacagtgac gggtcacatg atctcatcgg taccttccac
841 accagcttgg cccagctgca ggcagtcccg gctgagtttg aatgcatcca ccctgagaag
901 cagcagaaaa agaaaagcta caagaactct ggaactatcc gtgtcaagat ttgtcgggta
961 gaaacagagt actcctttct ggactatgtg atgggaggct gtcagatcaa cttcactgtg
1021 ggcgtggact tcactggctc caatggagac ccctcctcac ctgactccct acactacctg
1081 agtccaacag gggtcaatga gtacctgatg gcactgtgga gtgtgggcag cgtggttcag
1141 gactatgact cagacaagct gttccctgca tttggatttg gggcccaggt tccccctgac
1201 tggcaggtct cgcatgaatt tgccttgaat ttcaacccca gtaaccccta ctgtgcaggc
1261 atccagggca ttgtggatgc ctaccgccaa gccctgcccc aagttcgcct ctatggccct
1321 accaactttg cacccatcat caaccatgtg gccaggtttg cagcccaggc tgcacatcag
1381 gggactgcct cgcaatactt catgctgttg ctgctgactg atggtgctgt gacggatgtg
1441 gaagccacac gtgaggctgt ggtgcgtgcc tcgaacctgc ccatgtcagt gatcattgtg
1501 ggtgtgggtg gtgctgactt tgaggccatg gagcagctgg acgctgatgg tggacccctg
1561 catacacgtt ctgggcaggc tgctgcccgc gacattgtgc agtttgtacc ctaccgccgg
1621 ttccagaatg cccctcggga ggcattggca cagaccgtgc tcgcagaagt gcccacacaa
1681 ctggtctcat acttcagggc ccagggttgg gccccgctca agccacttcc accctcagcc
1741 aaggatcctg cacaggcccc ccaggcctag gttcccttgg aggctgtggc aagtcctcaa
1801 tcctgtgtcc cagaggtccc tntgggccac aacccaaccc ttctcactct cctcagtgct
1861 agcactttgt attttttgat acttttatac ttgtttctgc ttttgctgct cttgatccca
1921 cctttgctcc tgacaaccct cattcaataa agaccagtga agaccaaaaa aaaaaaaaaa
1981 aaaaa
//