LOCUS HSU83192 3995 bp mRNA linear HUM 14-JUL-1998
DEFINITION Homo sapiens post-synaptic density protein 95 (PSD95) mRNA,
complete cds.
ACCESSION U83192
VERSION U83192.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3995)
AUTHORS Stathakis,D.G., Hoover,K.B., You,Z. and Bryant,P.J.
TITLE Human postsynaptic density-95 (PSD95): location of the gene (DLG4)
and possible function in nonneural as well as in neural tissues
JOURNAL Genomics 44 (1), 71-82 (1997)
PUBMED 9286702
REFERENCE 2 (bases 1 to 3995)
AUTHORS Stathakis,D.G., Hoover,K.H., You,Z. and Bryant,P.J.
TITLE Direct Submission
JOURNAL Submitted (24-DEC-1996) Developmental Biology Center, University of
California, Irvine, 4240 Biological Sciences II, Irvine, CA
92697-2275, USA
REFERENCE 3 (bases 1 to 3995)
AUTHORS Stathakis,D.G., Hoover,K.H., You,Z. and Bryant,P.J.
TITLE Direct Submission
JOURNAL Submitted (14-JUL-1998) Developmental Biology Center, University of
California, Irvine, 4240 Biological Sciences II, Irvine, CA
92697-2275, USA
REMARK Sequence update by submitter
COMMENT On Jul 14, 1998 this sequence version replaced gi:1857478.
FEATURES Location/Qualifiers
source 1..3995
/db_xref="H-InvDB:HIT000221816"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="17"
/map="17p13.1"
/clone="P3-1"
/tissue_type="mammary"
/clone_lib="Clontech 5'-Stretch cDNA Library"
gene 1..3995
/gene="PSD95"
misc_feature 61..149
/gene="PSD95"
/note="encodes PDZ1 domain"
misc_feature 156..244
/gene="PSD95"
/note="encodes PDZ2 domain"
misc_feature 309..390
/gene="PSD95"
/note="encodes PDZ3 domain"
misc_feature 375..429
/gene="PSD95"
/note="encodes SH3 domain"
misc_feature 532..712
/gene="PSD95"
/note="encodes GUK domain"
CDS 860..3163
/gene="PSD95"
/note="similar to Rattus norvegicus PSD95/SAP90, GenBank
Accession Number D50621; membrane associated putative
guanylate kinase protein member"
/codon_start=1
/product="post-synaptic density protein 95"
/protein_id="AAC52113.1"
/translation="MSQRPRAPRSALWLLAPPLLRWAPPLLTVLHSDLFQALLDILDY
YEASLSESQKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEG
EMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSI
LFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIA
GGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALK
NTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSP
RRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADL
SGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDL
REQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDA
SDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSY
ETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYH
FVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQ
AAHLHPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSF
EEIYHKVKRVIEDLSGPYIWVPARERL"
BASE COUNT 901 a 1113 c 1160 g 821 t
ORIGIN
1 ggatccgcgg gacagatgag gaaggggctt aagtcactgc agccagaggg atggaggtgg
61 actgatggga gggcttctcc ggtggggtta gaagggaaaa gtagggaaag agaagtgtaa
121 ggtagatggc agaggcagag acatggaaag acagactcta gggttcctga tgatatctat
181 ctcggccaac acaaaaggga gggtacagtg gtgggggcac ccaagctagg gtgtgagtac
241 cctaagtgta ttcttctgag atgtaggcca ttcactaact cttggaacag ctacagtttc
301 acagtaggaa gaccccccca gattcactgc ccctccctta gtaaagcctc tgagaccttc
361 ctgaacattc ccttctgtct ttgccctctg ttccttccag agactatgtg cccaggcaga
421 tggattcctc ccgggcctga gaggaactgc aggaattctc ctgcctctta cccgtaaaac
481 cccaacttct ctagccctag ggcaggaagt cccaaacaat ttctacccct ttttctgcaa
541 ttctcattgg ggtgagagga ggcccaggag gagagagagc tgggctcagc ttctttttga
601 gctgctggag ccctctgtga ggaggccctc tttgctggct tctcaggaga gtgtggctag
661 gttctgcctg cctatgggaa gagggggcca gggtgtgtgg agcaagatgg tgcggtgctg
721 gtgccttggg acctggggga atgggacagc tggtcggctc agagacggcc tactttactc
781 acagctggaa tttagtgggg agaagcagct caactccaat cctggaggat tagggagatt
841 aaagtgagag aagagagaga tgtcccagag accaagagct cccaggtcag ccctctggct
901 cctggcaccc ccactgctgc ggtgggcacc cccactcctc acagtgctgc atagcgacct
961 cttccaggcc ttgctggaca tcctggacta ttatgaggct tccctctcag agagtcagaa
1021 ataccgctac caagatgaag acacgccccc tctggagcac agcccggccc acctccccaa
1081 ccaggccaat tctcccccag tgattgtcaa cacagatacc ctagaagccc caggatatga
1141 gttgcaggtg aacgggaccg agggggagat ggaatacgag gaaatcacat tggaaagggg
1201 taactcaggt ctgggcttca gcatcgcagg tggcactgac aacccacaca tcggtgacga
1261 cccatccatt ttcatcacca agatcattcc tggtggggct gcggcccagg atggccgcct
1321 cagggtcaac gacagcatcc tgtttgtaaa tgaagtggac gtgcgcgagg tgacccactc
1381 agcggcggtg gaagccctca aagaggcagg ctccatcgtt cgcctctatg tcatgcgccg
1441 gaagcccccg gctgagaagg tcatggagat caagctcatc aaggggccta aaggtcttgg
1501 cttcagcatc gcagggggcg tagggaacca gcacatccca ggagataata gcatctatgt
1561 aacaaagatc atcgaagggg gtgctgccca caaggatggg aggttgcaga ttggagacaa
1621 gatcctggcg gtcaacagtg tggggctaga ggacgtcatg catgaagatg ctgtggcagc
1681 cctgaagaac acgtatgatg ttgtctacct aaaggtggcc aagcccagca atgcctacct
1741 gagtgacagc tatgctcccc cagacatcac aacctcttat tcccagcacc tggacaatga
1801 gatcagtcac agcagctacc tgggcaccga ctaccccaca gccatgaccc ccacttcccc
1861 tcggcgctac tctccagtgg ccaaggacct gctcggggag gaagacattc cccgagaacc
1921 gaggcgaatt gtgatccacc ggggctccac gggcctgggc ttcaacatcg tgggtggcga
1981 ggacggtgaa ggcatcttca tctcctttat cctggccggg ggccctgcag acctcagtgg
2041 ggagctgcgg aagggggacc agatcctgtc ggtcaacggt gtggacctcc gaaatgccag
2101 ccatgagcag gctgccattg ccctgaagaa tgcgggtcag acggtcacga tcatcgctca
2161 gtataaacca gaagagtaca gccgattcga ggccaagatc cacgaccttc gggaacagct
2221 catgaacagc agcctgggct cagggactgc gtccttgcgg agcaacccca aaaggggttt
2281 ctacatcagg gccctgtttg attacgacaa gaccaaggac tgcggcttcc tgagccaggc
2341 cctgagcttc cgctttgggg atgtgctgca tgtcatcgat gctagtgatg aggagtggtg
2401 gcaggcacgg cgggtccact ctgacagtga gaccgacgac attgggttca tccccagcaa
2461 acggcgggtt gagcgacgag agtggtcaag gttaaaggcc aaggactggg gctccagctc
2521 tggatcgcag ggtcgagaag actcggttct gagctacgag acagtgacgc agatggaagt
2581 gcactatgct cgccccatca tcatccttgg gcccaccaag gaccgcgcca acgatgatct
2641 tctctccgag ttccccgaca agtttggatc ctgtgttccc catacgacac ggcccaagcg
2701 ggagtatgag atagatggcc gggattacca ctttgtgtcg tcccgggaga aaatggagaa
2761 ggacattcag gcgcacaagt tcattgaggc cggccagtac aacagccacc tctatgggac
2821 cagcgtccag tccgtgcgag aggtggcaga gcaggggaag cactgcatcc tcgatgtctc
2881 ggccaatgcc gtgcggcggc tgcaggcggc ccacctgcac cccatcgcca tcttcatccg
2941 cccccgctcc ctggagaatg tgctagagat taacaagcgg atcacagagg agcaagcccg
3001 caaagccttc gacagagcca ccaagctgga gcaggagttc acagagtgct tctcagccat
3061 cgtggagggt gacagctttg aggagatcta ccacaaggtg aagcgtgtca tcgaggacct
3121 ctcaggcccc tacatctggg ttccagcccg agagagactc tgattcctgc cctggcttgg
3181 cctggactcg ccctgcctcc atcacctggg cccttggtct ggactgaatt gcccaagccc
3241 ttggctcccc ccggcctccc tcccacccct tcttatttat ttcctttcta actggatcca
3301 gcctgttgga ggggggacac tcctctgcat gtatccccgc accccagaac tgggctcctg
3361 aacgccagga acctggggtc tgggggggag ctgggctcct tgttccgagc ccttgctcct
3421 taggatcccc gcccccacct gcccccaatg cacacacaga cccaccgggg gccacctgcc
3481 ctcccccatc ctctcccaca cacattccag aagtcagggc cccctcgagg agcacccgct
3541 gcagggatgc agggccacag gcctccgctc tctcctaagg cagggtctgg ggtcacccct
3601 gcctcatcgt aattccccat gttaccttga tttctcattt attttttcca ctttttttct
3661 tctcaaaggt ggttttttgg ggggagaagc aggggactcc gcagcgggcc cctgccttcc
3721 acatgccccc accatttttc tttgccggtt tgcatgagtg gaaggtctaa atgtggcttt
3781 tttttttttt ttcctgggaa tttttttggg gaaaagggag ggatgggtct agggagtggg
3841 aaatgcggga gggagggtgg ggcaggggtc gggggtcggg tgtccgggag ccagggaaga
3901 ctggaaatgc tgccgccttc tgcaatttat ttattttttt cttttgagag agtgaaagga
3961 agagacagat acttgaaaaa aaaaaaaaaa aaaaa
//