LOCUS HSU82130 1494 bp mRNA linear HUM 04-JUN-1998
DEFINITION Human tumor susceptiblity protein (TSG101) mRNA, complete cds.
ACCESSION U82130
VERSION U82130.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1494)
AUTHORS Li,L., Li,X., Francke,U. and Cohen,S.N.
TITLE The TSG101 tumor susceptibility gene is located in chromosome 11
band p15 and is mutated in human breast cancer
JOURNAL Cell 88 (1), 143-154 (1997)
PUBMED 9019400
REFERENCE 2 (bases 1 to 1494)
AUTHORS Li,L. and Cohen,S.N.
TITLE Direct Submission
JOURNAL Submitted (12-DEC-1996) Department of Genetics, Stanford University
School of Medicine, Stanford, CA 94305, USA
REFERENCE 3 (bases 1 to 1494)
AUTHORS Li,L. and Cohen,S.N.
TITLE Direct Submission
JOURNAL Submitted (04-JUN-1998) Department of Genetics, Stanford University
School of Medicine, Stanford, CA 94305, USA
REMARK Amino acid sequence updated by submitter
FEATURES Location/Qualifiers
source 1..1494
/db_xref="H-InvDB:HIT000221740"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="11"
/map="11p15"
gene 1..1494
/gene="TSG101"
CDS 91..1263
/gene="TSG101"
/codon_start=1
/product="tumor susceptibility protein"
/protein_id="AAC52083.1"
/translation="MAVSESQLKKMVSKYKYRDLTVRETVNVITLYKDLKPVLDSYVF
NDGSSRELMNLTGTIPVPYRGNTYNIPICLWLLDTYPYNPPICFVKPTSSMTIKTGKH
VDANGKIYLPYLHEWKHPQSDLLGLIQVMIVVFGDEPPVFSRPISASYPPYQATGPPN
TSYMPGMPGGISPYPSGYPPNPSGYPGCPYPPGGPYPATTSSQYPSQPPVTTVGPSRD
GTISEDTIRASLISAVSDKLRWRMKEEMDRAQAELNALKRTEEDLKKGHQKLEEMVTR
LDQEVAEVDKNIELLKKKDEELSSALEKMENQSENNDIDEVIIPTAPLYKQILNLYAE
ENAIEDTIFYLGEALRRGVIDLDVFLKHVRLLSRKQFQLRALMQKARKTAGLSDLY"
BASE COUNT 424 a 338 c 329 g 403 t
ORIGIN
1 gaagggtgtg cgattgtgtg ggacggtctg gggcagccca gcagcggctg accctctgcc
61 tgcggggaag ggagtcgcca ggcggccgtc atggcggtgt cggagagcca gctcaagaaa
121 atggtgtcca agtacaaata cagagaccta actgtacgtg aaactgtcaa tgttattact
181 ctatacaaag atctcaaacc tgttttggat tcatatgttt ttaacgatgg cagttccagg
241 gaactaatga acctcactgg aacaatccct gtgccttata gaggtaatac atacaatatt
301 ccaatatgcc tatggctact ggacacatac ccatataatc cccctatctg ttttgttaag
361 cctactagtt caatgactat taaaacagga aagcatgttg atgcaaatgg gaagatatat
421 cttccttatc tacatgaatg gaaacaccca cagtcagact tgttggggct tattcaggtc
481 atgattgtgg tatttggaga tgaacctcca gtcttctctc gtcctatttc ggcatcctat
541 ccgccatacc aggcaacggg gccaccaaat acttcctaca tgccaggcat gccaggtgga
601 atctctccat acccatccgg ataccctccc aatcccagtg gttacccagg ctgtccttac
661 ccacctggtg gtccatatcc tgccacaaca agttctcagt acccttctca gcctcctgtg
721 accactgttg gtcccagtag ggatggcaca atcagcgagg acaccatccg agcctctctc
781 atctctgcgg tcagtgacaa actgagatgg cggatgaagg aggaaatgga tcgtgcccag
841 gcagagctca atgccttgaa acgaacagaa gaagacctga aaaagggtca ccagaaactg
901 gaagagatgg ttacccgttt agatcaagaa gtagccgagg ttgataaaaa catagaactt
961 ttgaaaaaga aggatgaaga actcagttct gctctggaaa aaatggaaaa tcagtctgaa
1021 aacaatgata tcgatgaagt tatcattccc acagctccct tatacaaaca gatcctgaat
1081 ctgtatgcag aagaaaacgc tattgaagac actatctttt acttgggaga agccttgaga
1141 aggggcgtga tagacctgga tgtcttcctg aagcatgtac gtcttctgtc ccgtaaacag
1201 ttccagctga gggcactaat gcaaaaagca agaaagactg ccggtctcag tgacctctac
1261 tgacttctct gataccagct ggaggttgag ctcttcttaa agtattcttc tcttcctttt
1321 atcagtaggt gcccagaata agttattgca gtttatcatt caagtgtaaa atattttgaa
1381 tcaataatat attttctgtt ttcttttggt aaagactggc ttttattaat gcactttcta
1441 tcctctgtaa actttttgtg ctgaatgttg ggactgctaa ataaaatttg tttt
//