LOCUS HSU81984 2818 bp mRNA linear HUM 28-JAN-1997
DEFINITION Human endothelial PAS domain protein 1 (EPAS1) mRNA, complete cds.
ACCESSION U81984
VERSION U81984.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2818)
AUTHORS Tian,H., McKnight,S.L. and Russell,D.W.
TITLE Endothelial PAS domain protein 1 (EPAS1), a transcription factor
selectively expressed in endothelial cells
JOURNAL Genes Dev. 11 (1), 72-82 (1997)
PUBMED 9000051
REFERENCE 2 (bases 1 to 2818)
AUTHORS Tian,H., McKnight,S.L. and Russell,D.W.
TITLE Direct Submission
JOURNAL Submitted (11-DEC-1996) Molecular Genetics, University of Texas
Southwestern Medical Center, 5323 Harry Hines Blvd., Dallas, TX
75235, USA
FEATURES Location/Qualifiers
source 1..2818
/db_xref="H-InvDB:HIT000221735"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
gene 1..2818
/gene="EPAS1"
CDS 150..2762
/gene="EPAS1"
/note="bHLH-PAS"
/codon_start=1
/product="endothelial PAS domain protein 1"
/protein_id="AAB41495.1"
/translation="MTADKEKKRSSSERRKEKSRDAARCRRSKETEVFYELAHELPLP
HSVSSHLDKASIMRLEISFLRTHKLLSSVCSENESEAEADQQMDNLYLKALEGFIAVV
TQDGDMIFLSENISKFMGLTQVELTGHSIFDFTHPCDHEEIRENLSLKNGSGFGKKSK
DMSTERDFFMRMKCTVTNRGRTVNLKSATWKVLHCTGQVKVYNNCPPHNSLCGYKEPL
LSCLIIMCEPIQHPSHMDIPLDSKTFLSRHSMDMKFTYCDDRITELIGYHPEELLGRS
AYEFYHALDSENMTKSHQNLCTKGQVVSGQYRMLAKHGGYVWLETQGTVIYNPRNLQP
QCIMCVNYVLSEIEKNDVVFSMDQTESLFKPHLMAMNSIFDSSGKGAVSEKSNFLFTK
LKEEPEELAQLAPTPGDAIISLDFGNQNFEESSAYGKAILPPSQPWATELRSHSTQSE
AGSLPAFTVPQAAAPGSTTPSATSSSSSCSTPNSPEDYYTSLDNDLKIEVIEKLFAMD
TEAKDQCSTQTDFNELDLETLAPYIPMDGEDFQLSPICPEERLLAENPQSTPQHCFSA
MTNIFQPLAPVAPHSPFLLDKFQQQLESKKTEPEHRPMSSIFFDAGSKASLPPCCGQA
STPLSSMGGRSNTQWPPDPPLHFGPTKWAVGDQRTEFLGAAPLGPPVSPPHVSTFKTR
SAKGFGARGPDVLSPAMVALSNKLKLKRQLEYEEQAFQDLSGGDPPGGSTSHLMWKRM
KNLRGGSCPLMPDKPLSANVPNDKFTQNPMRGLGHPLRHLPLPQPPSAISPGENSKSR
FPPQCYATQYQDYSLSSAHKVSGMASRLLGPSFESYLLPELTRYDCEVNVPVLGSSTL
LQGGDLLRALDQAT"
BASE COUNT 669 a 882 c 764 g 503 t
ORIGIN
1 cctgactgcg cggggcgctc gggacctgcg cgcacctcgg accttcacca cccgcccggg
61 ccgcggggag cggacgaggg ccacagcccc ccacccgcca gggagcccag gtgctcggcg
121 tctgaacgtc tcaaagggcc acagcgacaa tgacagctga caaggagaag aaaaggagta
181 gctcggagag gaggaaggag aagtcccggg atgctgcgcg gtgccggcgg agcaaggaga
241 cggaggtgtt ctatgagctg gcccatgagc tgcctctgcc ccacagtgtg agctcccatc
301 tggacaaggc ctccatcatg cgactggaaa tcagcttcct gcgaacacac aagctcctct
361 cctcagtttg ctctgaaaac gagtccgaag ccgaagctga ccagcagatg gacaacttgt
421 acctgaaagc cttggagggt ttcattgccg tggtgaccca agatggcgac atgatctttc
481 tgtcagaaaa catcagcaag ttcatgggac ttacacaggt ggagctaaca ggacatagta
541 tctttgactt cactcatccc tgcgaccatg aggagattcg tgagaacctg agtctcaaaa
601 atggctctgg ttttgggaaa aaaagcaaag acatgtccac agagcgggac ttcttcatga
661 ggatgaagtg cacggtcacc aacagaggcc gtactgtcaa cctcaagtca gccacctgga
721 aggtcttgca ctgcacgggc caggtgaaag tctacaacaa ctgccctcct cacaatagtc
781 tgtgtggcta caaggagccc ctgctgtcct gcctcatcat catgtgtgaa ccaatccagc
841 acccatccca catggacatc cccctggata gcaagacctt cctgagccgc cacagcatgg
901 acatgaagtt cacctactgt gatgacagaa tcacagaact gattggttac caccctgagg
961 agctgcttgg ccgctcagcc tatgaattct accatgcgct agactccgag aacatgacca
1021 agagtcacca gaacttgtgc accaagggtc aggtagtaag tggccagtac cggatgctcg
1081 caaagcatgg gggctacgtg tggctggaga cccaggggac ggtcatctac aaccctcgca
1141 acctgcagcc ccagtgcatc atgtgtgtca actacgtcct gagtgagatt gagaagaatg
1201 acgtggtgtt ctccatggac cagactgaat ccctgttcaa gccccacctg atggccatga
1261 acagcatctt tgatagcagt ggcaaggggg ctgtgtctga gaagagtaac ttcctattca
1321 ccaagctaaa ggaggagccc gaggagctgg cccagctggc tcccacccca ggagacgcca
1381 tcatctctct ggatttcggg aatcagaact tcgaggagtc ctcagcctat ggcaaggcca
1441 tcctgccccc gagccagcca tgggccacgg agttgaggag ccacagcacc cagagcgagg
1501 ctgggagcct gcctgccttc accgtgcccc aggcagctgc cccgggcagc accaccccca
1561 gtgccaccag cagcagcagc agctgctcca cgcccaatag ccctgaagac tattacacat
1621 ctttggataa cgacctgaag attgaagtga ttgagaagct cttcgccatg gacacagagg
1681 ccaaggacca atgcagtacc cagacggatt tcaatgagct ggacttggag acactggcac
1741 cctatatccc catggacggg gaagacttcc agctaagccc catctgcccc gaggagcggc
1801 tcttggcgga gaacccacag tccacccccc agcactgctt cagtgccatg acaaacatct
1861 tccagccact ggcccctgta gccccgcaca gtcccttcct cctggacaag tttcagcagc
1921 agctggagag caagaagaca gagcccgagc accggcccat gtcctccatc ttctttgatg
1981 ccggaagcaa agcatccctg ccaccgtgct gtggccaggc cagcacccct ctctcttcca
2041 tggggggcag atccaatacc cagtggcccc cagatccacc attacatttt gggcccacaa
2101 agtgggccgt cggggatcag cgcacagagt tcttgggagc agcgccgttg gggccccctg
2161 tctctccacc ccatgtctcc accttcaaga caaggtctgc aaagggtttt ggggctcgag
2221 gcccagacgt gctgagtccg gccatggtag ccctctccaa caagctgaag ctgaagcgac
2281 agctggagta tgaagagcaa gccttccagg acctgagcgg gggggaccca cctggtggca
2341 gcacctcaca tttgatgtgg aaacggatga agaacctcag gggtgggagc tgccctttga
2401 tgccggacaa gccactgagc gcaaatgtac ccaatgataa gttcacccaa aaccccatga
2461 ggggcctggg ccatcccctg agacatctgc cgctgccaca gcctccatct gccatcagtc
2521 ccggggagaa cagcaagagc aggttccccc cacagtgcta cgccacccag taccaggact
2581 acagcctgtc gtcagcccac aaggtgtcag gcatggcaag ccggctgctc gggccctcat
2641 ttgagtccta cctgctgccc gaactgacca gatatgactg tgaggtgaac gtgcccgtgc
2701 tgggaagctc cacgctcctg caaggagggg acctcctcag agccctggac caggccacct
2761 gagccaggcc ttctacctgg gcagcacctc tgccgacgcc gtcccaccag cttcaccc
//