LOCUS HSU81607 6608 bp mRNA linear HUM 26-JUN-1997
DEFINITION Homo sapiens gravin mRNA, complete cds.
ACCESSION U81607
VERSION U81607.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 6608)
AUTHORS Nauert,J.B., Klauck,T.M., Langeberg,L.K. and Scott,J.D.
TITLE Gravin, an autoantigen recognized by serum from myasthenia gravis
patients, is a kinase scaffold protein
JOURNAL Curr. Biol. 7 (1), 52-62 (1997)
PUBMED 9000000
REFERENCE 2 (bases 1 to 6608)
AUTHORS Nauert,J.B., Klauck,T.K., Langeberg,L.K. and Scott,J.D.
TITLE Direct Submission
JOURNAL Submitted (10-DEC-1996) Biochemistry, OHSU, 3181 SW Sam Jackson
Parkway, Portland, OR 97201, USA
COMMENT On Jun 26, 1997 this sequence version replaced gi:1850362.
FEATURES Location/Qualifiers
source 1..6608
/db_xref="H-InvDB:HIT000221730"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
CDS 192..5537
/note="kinase scaffold protein"
/codon_start=1
/product="gravin"
/protein_id="AAC51366.1"
/translation="MGAGSSTEQRSPEQPPEGSSTPAEPEPSGGGPSAEAAPDTTADP
AIAASDPATKLLQKNGQLSTINGVAEQDELSLQEGDLNGQKGALNGQGALNSQEEEEV
IVTEVGQRDSEDVSERDSDKEMATKSAVVHDITDDGQEENRNIEQIPSSESNLEELTQ
PTESQANDIGFKKVFKFVGFKFTVKKDKTEKPDTVQLLTVKKDEGEGAAGAGDHQDPS
LGAGEAASKESEPKQSTEKPEETLKREQSHAEISPPAESGQAVEECKEEGEEKQEKEP
SKSAESPTSPVTSETGSTFKKFFTQGWAGWRKKTSFRKPKEDEVEASEKKKEQEPEKV
DTEEDGKAEVASEKLTASEQAHPQEPAESAHEPRLSAEYEKVELPSEEQVSGSQGPSE
EKPAPLATEVFDEKIEVHQEEVVAEVHVSTVEERTEEQKTEVEETAGSVPAEELVGMD
AEPQEAEPAKELVKLKETCVSGEDPTQGADLSPDEKVLSKPPEGVVSEVEMLSSQERM
KVQGSPLKKLFTSTGLKKLSGKKQKGKRGGGDEESGEHTQVPADSPDSQEEQKGESSA
SSPEEPEEITCLEKGLAEVQQDGEAEEGATSDGEKKREGVTPWASFKKMVTPKKRVRR
PSESDKEDELDKVKSATLSSTESTASEMQEEMKGSVEEPKPEEPKRKVDTSVSWEALI
CVGSSKKRARRRSSSDEEGGPKAMGGDHQKADEAGKDKETGTDGILAGSQEHDPGQGS
SSPEQAGSPTEGEGVSTWESFKRLVTPRKKSKSKLEEKSEDSIAGSGVEHSTPDTEPG
KEESWVSIKKFIPGRRKKRPDGKQEQAPVEDAGPTGANEDDSDVPAVVPLSEYDAVER
EKMEAQQAQKGAEQPEQKAATEVSKELSESQVHMMAAAVADGTRAATIIEERSPSWIS
ASVTEPLEQVEAEAALLTEEVLEREVIAEEEPPTVTEPLPENREARGDTVVSEAELTP
EAVTAAETAGPLGSEEGTEASAAEETTEMVSAVSQLTDSPDTTEEATPVQEVEGGVPD
IEEQERRTQEVLQAVAEKVKEESQLPGTGGPEDVLQPVQRAEAERPEEQAEASGLKKE
TDVVLKVDAQEAKTEPFTQGKVVGQTTPESFEKAPQVTESIESSELVTTCQAETLAGV
KSQEMVMEQAIPPDSVETPTDSETDGSTPVADFDAPGTTQKDEIVEIHEENEVASGTQ
SGGTEAEAVPAQKERPPAPSSFVFQEETKEQSKMEDTLEHTDKEVSVETVSILSKTEG
TQEADQYADEKTKDVPFFEGLEGSIDTGITVSREKVTEVALKGEGTEEAECKKDDALE
LQSHAKSPPSPVEREMVVQVEREKTEAEPTHVNEEKLEHETAVTVSEEVSKQLLQTVN
VPIIDGAKEVSSLEGSPPPCLGQEEAVCTKIQVQSSEASFTLTAAAEEEKVLGETANI
LETGETLEPAGAHLVLEEKSSEKNEDFAAHPGEDAVPTGPDCQAKSTPVIVSATTKKG
LSSDLEGEKTTSLKWKSDEVDEQVACQEVKVSVAIEDLEPENGILELETKSSKLVQNI
IQTAVDQFVRTEETATEMLTSELQTQAHVIKADSQDAGQETEKEGEEPQASAQDETPI
TSAKEESESTAVGQAHSDISKDMSEASEKTMTVEVEGSTVNDQQLEEVVLPSEEEGGG
AGTKSVPEDDGHALLAERIEKSLVEPKEDEKGDDVDDPENQNSALADTDASGGLTKES
PDTNGPKQKEKEDAQEVELQEGKVHSESDKAITPQAQEELQKQERESAKSELTES"
BASE COUNT 2091 a 1418 c 1827 g 1272 t
ORIGIN
1 ccttctttta aggagtttgc cgcgagcgcg tctccttcat tcgcaggctg ggcgcgttcg
61 cagtcggctg gcggcgaagg aaggcgctct cgggacctca cgggcgcgcg tcttttggct
121 cttgcccctg tccctgcggc ttggggaaag cgtaacccgg cggctaggcg cgggagaagt
181 gcggaggagc catgggcgcc gggagctcca ccgagcagcg cagcccggag cagccgcccg
241 aggggagctc cacgccggct gagcccgagc ccagcggcgg cggcccctcg gccgaggcgg
301 cgccagacac caccgcggac cccgccatcg ctgcctcgga ccccgccacc aagctcctac
361 agaagaatgg tcagctgtcc accatcaatg gcgtagctga gcaagatgag ctcagcctcc
421 aggagggtga cctaaatggc cagaaaggag ccctgaacgg tcaaggagcc ctaaacagcc
481 aggaggaaga agaagtcatt gtcacggagg ttggacagag agactctgaa gatgtgagcg
541 aaagagactc cgataaagag atggctacta agtcagcggt tgttcacgac atcacagatg
601 atgggcagga ggagaaccga aatatcgaac agattccttc ttcagaaagc aatttagaag
661 agctaacaca acccactgag tcccaggcta atgatattgg atttaagaag gtgtttaagt
721 ttgttggctt taaattcact gtgaaaaagg ataagacaga gaagcctgac actgtccagc
781 tactcactgt gaagaaagat gaaggggagg gagcagcagg ggctggcgac caccaggacc
841 ccagccttgg ggctggagaa gcagcatcca aagaaagcga acccaaacaa tctacagaga
901 aacccgaaga gaccctgaag cgtgagcaaa gccacgcaga aatttctccc ccagccgaat
961 ctggccaagc agtggaggaa tgcaaagagg aaggagaaga gaaacaagaa aaagaaccta
1021 gcaagtctgc agaatctccg actagtcccg tgaccagtga aacaggatca accttcaaaa
1081 aattcttcac tcaaggttgg gccggctggc gcaaaaagac cagtttcagg aagccgaagg
1141 aggatgaagt ggaagcttca gagaagaaaa aggaacaaga gccagaaaaa gtagacacag
1201 aagaagacgg aaaggcagag gttgcctccg agaaactgac cgcctccgag caagcccacc
1261 cacaggagcc ggcagaaagt gcccacgagc cccggttatc agctgaatat gagaaagttg
1321 agctgccctc agaggagcaa gtcagtggct cgcagggacc ttctgaagag aaacctgctc
1381 cgttggcgac agaagtgttt gatgagaaaa tagaagtcca ccaagaagag gttgtggccg
1441 aagtccacgt cagcaccgtg gaggagagaa ccgaagagca gaaaacggag gtggaagaaa
1501 cagcagggtc tgtgccagct gaagaattgg ttggaatgga tgcagaacct caggaagccg
1561 aacctgccaa ggagctggtg aagctcaaag aaacgtgtgt ttccggagag gaccctacac
1621 agggagctga cctcagtcct gatgagaagg tgctgtccaa accccccgaa ggcgttgtga
1681 gtgaggtgga aatgctgtca tcacaggaga gaatgaaggt gcagggaagt ccactaaaga
1741 agctttttac cagcactggc ttaaaaaagc tttctggaaa gaaacagaaa gggaaaagag
1801 gaggaggaga cgaggaatca ggggagcaca ctcaggttcc agccgattct ccggacagcc
1861 aggaggagca aaagggcgag agctctgcct catcccctga ggagcccgag gagatcacgt
1921 gtctggaaaa gggcttagcc gaggtgcagc aggatgggga agctgaagaa ggagctactt
1981 ccgatggaga gaaaaaaaga gaaggtgtca ctccctgggc atcattcaaa aagatggtga
2041 cgcccaagaa gcgtgttaga cggccttcgg aaagtgataa agaagatgag ctggacaagg
2101 tcaagagcgc taccttgtct tccaccgaga gcacagcctc tgaaatgcaa gaagaaatga
2161 aagggagcgt ggaagagcca aagccggaag aaccaaagcg caaggtggat acctcagtat
2221 cttgggaagc tttaatttgt gtgggatcat ccaagaaaag agcaaggaga aggtcctctt
2281 ctgatgagga agggggacca aaagcaatgg gaggagacca ccagaaagct gatgaggccg
2341 gaaaagacaa agagacgggg acagacggga tccttgctgg ttcccaagaa catgatccag
2401 ggcagggaag ttcctccccg gagcaagctg gaagccctac cgaaggggag ggcgtttcca
2461 cctgggagtc atttaaaagg ttagtcacgc caagaaaaaa atcaaagtcc aagctggaag
2521 agaaaagcga agactccata gctgggtctg gtgtagaaca ttccactcca gacactgaac
2581 ccggtaaaga agaatcctgg gtctcaatca agaagtttat tcctggacga aggaagaaaa
2641 ggccagatgg gaaacaagaa caagcccctg ttgaagacgc agggccaaca ggggccaacg
2701 aagatgactc tgatgtcccg gccgtggtcc ctctgtctga gtatgatgct gtagaaaggg
2761 agaaaatgga ggcacagcaa gcccaaaaag gcgcagagca gcccgagcag aaggcagcca
2821 ctgaggtgtc caaggagctc agcgagagtc aggttcatat gatggcagca gctgtcgctg
2881 acgggacgag ggcagctacc attattgaag aaaggtctcc ttcttggata tctgcttcag
2941 tgacagaacc tcttgaacaa gtagaagctg aagccgcact gttaactgag gaggtattgg
3001 aaagagaagt aattgcagaa gaagaacccc ccacggttac tgaacctctg ccagagaaca
3061 gagaggcccg gggcgacacg gtcgttagtg aggcggaatt gacccccgaa gctgtgacag
3121 ctgcagaaac tgcagggcca ttgggttccg aagaaggaac cgaagcatct gctgctgaag
3181 agaccacaga aatggtgtca gcagtctccc agttaaccga ctccccagac accacagagg
3241 aggccactcc ggtgcaggag gtggaaggtg gcgtacctga catagaagag caagagaggc
3301 ggactcaaga ggtcctccag gcagtggcag aaaaagtgaa agaggaatcc cagctgcctg
3361 gcaccggtgg gccagaagat gtgcttcagc ctgtgcagag agcagaggca gaaagaccag
3421 aagagcaggc tgaagcgtcg ggtctgaaga aagagacgga tgtagtgttg aaagtagatg
3481 ctcaggaggc aaaaactgag ccttttacac aagggaaggt ggtggggcag accaccccag
3541 aaagctttga aaaagctcct caagtcacag agagcataga gtccagtgag cttgtaacca
3601 cttgtcaagc cgaaacctta gctggggtaa aatcacagga gatggtgatg gaacaggcta
3661 tcccccctga ctcggtggaa acccctacag acagtgagac tgatggaagc acccccgtag
3721 ccgactttga cgcaccaggc acaacccaga aagacgagat tgtggaaatc catgaggaga
3781 atgaggtcgc atctggtacc cagtcagggg gcacagaagc agaggcagtt cctgcacaga
3841 aagagaggcc tccagcacct tccagttttg tgttccagga agaaactaaa gaacaatcaa
3901 agatggaaga cactctagag catacagata aagaggtgtc agtggaaact gtatccattc
3961 tgtcaaagac tgaggggact caagaggctg accagtatgc tgatgagaaa accaaagacg
4021 taccattttt cgaaggactt gaggggtcta tagacacagg cataacagtc agtcgggaaa
4081 aggtcactga agttgccctt aaaggtgaag ggacagaaga agctgaatgt aaaaaggatg
4141 atgctcttga actgcagagt cacgctaagt ctcctccatc ccccgtggag agagagatgg
4201 tagttcaagt cgaaagggag aaaacagaag cagagccaac ccatgtgaat gaagagaagc
4261 ttgagcacga aacagctgtt accgtatctg aagaggtcag taagcagctc ctccagacag
4321 tgaatgtgcc catcatagat ggggcaaagg aagtcagcag tttggaagga agccctcctc
4381 cctgcctagg tcaagaggag gcagtatgca ccaaaattca agttcagagc tctgaggcat
4441 cattcactct aacagcggct gcagaggagg aaaaggtctt aggagaaact gccaacattt
4501 tagaaacagg tgaaacgttg gagcctgcag gtgcacattt agttctggaa gagaaatcct
4561 ctgaaaaaaa tgaagacttt gccgctcatc caggggaaga tgctgtgccc acagggcccg
4621 actgtcaggc aaaatcgaca ccagtgatag tatctgctac taccaagaaa ggcttaagtt
4681 ccgacctgga aggagagaaa accacatcac tgaagtggaa gtcagatgaa gtcgatgagc
4741 aggttgcttg ccaggaggtc aaagtgagtg tagcaattga ggatttagag cctgaaaatg
4801 ggattttgga acttgagacc aaaagcagta aacttgtcca aaacatcatc cagacagccg
4861 ttgaccagtt tgtacgtaca gaagaaacag ccaccgaaat gttgacgtct gagttacaga
4921 cacaagctca cgtgataaaa gctgacagcc aggacgctgg acaggaaacg gagaaagaag
4981 gagaggaacc tcaggcctct gcacaggatg aaacaccaat tacttcagcc aaagaggagt
5041 cagagtcaac cgcagtggga caagcacatt ctgatatttc caaagacatg agtgaagcct
5101 cagaaaagac catgactgtt gaggtagaag gttccactgt aaatgatcag cagctggaag
5161 aggtcgtcct cccatctgag gaagagggag gtggagctgg aacaaagtct gtgccagaag
5221 atgatggtca tgccttgtta gcagaaagaa tagagaagtc actagttgaa ccgaaagaag
5281 atgaaaaagg tgatgatgtt gatgaccctg aaaaccagaa ctcagccctg gctgatactg
5341 atgcctcagg aggcttaacc aaagagtccc cagatacaaa tggaccaaaa caaaaagaga
5401 aggaggatgc ccaggaagta gaattgcagg aaggaaaagt gcacagtgaa tcagataaag
5461 cgatcacacc ccaagcacag gaggagttac agaaacaaga gagagaatct gcaaagtcag
5521 aacttacaga atcttaaaac atcatgcagt taaactcatt gtctgtttgg aagaccagaa
5581 tgtgaagaca agtagtagaa gaaaatgaat gctgctgctg agactgaaga ccagtatttc
5641 agaactttga gaattggaga gcaggcacat caactgatct catttctaga gagcccctga
5701 caatcctgag gcttcatcag gagctagagc catttaacat ttcctctttc caagaccaac
5761 ctacaatttt cccttgataa ccatataaat tctgatttaa ggtcctaaat tcttaacctg
5821 gaactggagt tggcaatacc tagttctgct tctgaaactg gagtatcatt ctttacatat
5881 ttatatgtat gttttaagta gtcctcctgt atctattgta tatttttttc ttaatgttta
5941 aggaaatgtg caggatacta catgcttttt gtatcacaca gtatatgatg gggcatgtgc
6001 catagtgcag gcttggggag ctttaagcct cagttatata acccacaaaa aacagagcct
6061 cctagatgta acattcctga tcaaggtaca attctttaaa attcactaat gattgaggtc
6121 catatttagt ggtactctga aattggtcac tttcctatta cacggagtgt gccaaaacta
6181 aaaagcattt tgaaacatac agaatgttct attgtcattg ggaaattttg ctttctaacc
6241 cagtggaggt tagaaagaag ttatattctg gtagcaaatt aactttacat cctttttcct
6301 acttgttatg gttgtttgga ccgataagtg tgcttaatcc tgaggcaaag tagtgaatat
6361 gttttatatg ttatgaagaa aagaattgtt gtaagttttt gattctactc ttatatgctg
6421 gactgcattc acacatggca tgaaataagt caggttcttt acaaatggta ttttgataga
6481 tactggattg tgtttgtgcc atatttgtgc cattccttta agaacaatgt tgcaacacat
6541 tcatttggat aagttgtgat ttgacgactg atttaaataa aatatttgct tcacttaaaa
6601 aaaaaaaa
//