LOCUS HSU80742 3103 bp mRNA linear HUM 18-DEC-1997
DEFINITION Homo sapiens CAGH45 mRNA, complete cds.
ACCESSION U80742
VERSION U80742.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3103)
AUTHORS Margolis,R.L., Abraham,M.R., Gatchell,S.B., Li,S.H., Kidwai,A.S.,
Breschel,T.S., Stine,O.C., Callahan,C., McInnis,M.G. and Ross,C.A.
TITLE cDNAs with long CAG trinucleotide repeats from human brain
JOURNAL Hum. Genet. 100 (1), 114-122 (1997)
PUBMED 9225980
REFERENCE 2 (bases 1 to 3103)
AUTHORS Margolis,R.L., Abraham,M.R., Gatchell,S.B., Li,S.H., Kidwai,A.S.,
Breschel,T.S., Stine,O.C., Callahan,C., McInnis,M.G. and Ross,C.A.
TITLE Direct Submission
JOURNAL Submitted (02-DEC-1996) Psychiatry, Johns Hopkins Univ. Sch. of
Med., 600 N. Wolfe Street, Meyer 2-181, Baltimore, MD 21205, USA
FEATURES Location/Qualifiers
source 1..3103
/db_xref="H-InvDB:HIT000221581"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="1"
/tissue_type="brain"
/dev_stage="fetus"
gene 1..3103
/gene="CAGH45"
CDS 826..2784
/gene="CAGH45"
/note="glutamine rich"
/codon_start=1
/product="CAGH45"
/protein_id="AAB91440.1"
/translation="MHEALKLRLNLVGGMFDTVQRSTQQTTEWAMLLLEIIISGTVDM
QSNNELFTTVLDMLSVLINGTLAADMSSISQGSMEENKRAYMNLAKKLQKELGERQSD
SLEKVRQLLPLPKQTRDVITCEPQGSLIDTKGNKIAGFDSIFKKEGLQVSTKQKISPW
DLFEGLKPSAPLSWGWFGTVRVDRRVARGEEQQRLLLYHTHLRPRPRAYYLEPLPLPP
EDEEPPAPTLLEPEKKAPEPPKTDKPGAAPPSTEERKKKSTKGKKRSQPATKTEDYGM
GPGRSGPYGVTVPPDLLHHPNPGSITHLNYRQGSIGLYTQNQPLPAGGPRVDPYRPVR
LPMQKLPTRPTYPGVLPTTMTGVMGLEPSSYKTSVYRQQQPAVPQGQRLRQQLQAKIQ
SQGMLGQSSVHQMTPSSSYGLQTSQGYTPYVSHVGLQQHTGPAGTMVPPSYSSQPYQS
THPSTNPTLVDPTRHLQQRPSGYVHQQAPTYGHGLTSTQRFSHQTLQQTPMISTMTPM
SAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQ
QQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQTQQQQ
QTAALVRQLQQQLSNTQPQPSTNIFGRY"
repeat_region 2401..2508
/gene="CAGH45"
/note="interrupted CAG repeat; 25 consecutive glutamine
amino acids"
/rpt_type=tandem
/rpt_unit_seq="cag"
repeat_region 2518..2619
/gene="CAGH45"
/note="interrupted CAG repeat; 25 consecutive glutamine
amino acids"
/rpt_type=tandem
/rpt_unit_seq="cag"
BASE COUNT 856 a 914 c 769 g 563 t
ORIGIN
1 ttccggtggc agtggtggtc ggaggcaggg tggccgcaac atctctgtgg agacagccag
61 tctggatgtc tatgccaagt acgtgctgcg cagcatctgc caacaggaat gggtaggaga
121 acgttgcctt aagtctctgt gtgaggacag caatgacctg caagacccag tgttgagtag
181 tgcccaggcg cagcgcctca tgcagctcat ttgctatcca catcgactgc tggacaatga
241 ggatggggaa aacccccagc ggcagcgcat aaagcgcatt ctccagaact tggaccagtg
301 gaccatgcgc cagtcttcct tggagctgca gctcatgatc aaagcagacc cctaacaatg
361 agattgaact ccctcttgga ggaacatcgc caaggccaca atcgaggttt tccaacagtc
421 agcagagaca gggtcatctt cctggaagta ctgcaagcaa catgccagca gcagcaagac
481 caagcctgtg ctcagctctc tagagcgctc tggtgtatgg ctggtggccc ccctcattgc
541 taaactgccc acctcagtcc agggacatgt gttaaaggct gctggggaag aattggagaa
601 gggtcagcac ctgggttcct cttcacgcaa agaacgtgat cgacaaaagc agaagagcat
661 gtccctattg agccagcagc ccttcttatc gctggtgcta acatgtctga aagggcagga
721 tgaacaacgc gagggactcc ttacctccct ctacagccag gtgcaccaga ttgtgaataa
781 ttggcgagat gacagtactt agatgattgc aaaccaaagc agcttatgca tgaggcactc
841 aaactgcggc tcaacctggt ggggggcatg tttgacacgg tgcagcgcag cacccagcag
901 accacggagt gggccatgct cctcctggag atcatcatca gcggcactgt cgacatgcag
961 tccaacaatg agctcttcac tactgtgttg gacatgctga gcgtgctcat caatgggaca
1021 ttggctgcag acatgtctag catctcgcaa ggtagcatgg aggaaaacaa gcgtgcatac
1081 atgaacctgg cgaagaagtt gcagaaggag ttgggggagc gccagtcaga cagtctggaa
1141 aaggttcgcc agctgctgcc actgcccaag cagacccgag atgtcatcac gtgtgagcca
1201 cagggctccc ttatcgatac caagggcaac aagattgctg gcttcgattc catcttcaag
1261 aaggagggtc tacaggtttc caccaaacag aagatctcgc cctgggatct ttttgagggg
1321 ttgaagccgt cagcaccact ctcttggggc tggtttggaa cagtccgagt ggaccggcga
1381 gtggctcgag gagaggagca gcagcggttg ctgctctacc acacacacct gaggccccgg
1441 ccccgcgcct attacctgga gccactgcca ctgcccccag aagatgagga gccgcctgct
1501 cctaccctgc tagagcctga gaaaaaggct ccagagcccc ccaaaactga caaaccgggg
1561 gctgctccac ccagtactga ggaacgcaag aagaagtcca ccaagggcaa gaaacgcagc
1621 cagccagcta ccaagacaga ggactatgga atgggcccgg gtcggagcgg cccttatggt
1681 gtgacagtgc ctccggacct cctgcaccac ccaaaccctg gttctataac acaccttaac
1741 tacaggcaag gctccatagg cctgtacacc cagaaccagc cactacctgc aggtggccct
1801 cgtgtggacc cataccgtcc tgtgcgctta ccaatgcaga agctgcccac ccgaccaact
1861 taccctggag tgctgcccac aaccatgact ggcgtcatgg gtttagaacc ctcctcttat
1921 aagacctctg tgtaccggca gcagcaacct gcggtgcccc aaggacagcg ccttcgccaa
1981 cagctccagg caaagataca gagtcagggc atgttgggac agtcatctgt ccatcagatg
2041 actcccagct cttcctacgg tttgcagact tcccagggct atactcctta tgtttctcat
2101 gtgggattgc agcaacacac aggccctgca ggtaccatgg tgccccccag ctactccagc
2161 cagccttacc agagcaccca cccttctacc aatcctactc ttgtagatcc tacccgccac
2221 ctgcaacagc ggcccagtgg ctatgtgcac cagcaggccc ccacctatgg acatggactg
2281 acctccactc aaaggttttc acaccagaca ctgcagcaga cacccatgat aagtaccatg
2341 actccaatga gtgcccaggg cgtccaggca ggcgtccgtt caacagccat cctacctgag
2401 cagcagcagc agcagcaaca gcagcaacag caacagcagc agcagcagca acagcaacag
2461 cagcagcagc agcagcagta ccacatccgg cagcagcagc agcagcagat cctgcggcag
2521 cagcagcaac agcaacagca gcagcagcag cagcagcaac agcaacagca gcagcagcaa
2581 cagcaacaac agcaacacca gcagcaacag cagcaacagg cggctcctcc ccaaccccag
2641 ccccagtccc agccccagtt ccagcgccag gggcttcagc agacccagca gcagcaacag
2701 acagcagctt tggtccggca acttcaacaa cagctctcta atacccagcc acagcccagt
2761 accaacatat ttggacgcta ctgagccacc tggaggarct gcttgtgcac tggatgtggc
2821 cccacccttt cctcttaatt cccaatccca ttcctgggct agcaccagta gtggttgggg
2881 ccctcccctc aggctccatt tttaataagt ttttagtatt tttgttaatg tgaggcattg
2941 agctgttggg ttttgtatat tatttatata gagaccccag agctgttgca cccaatacac
3001 agagcttctt tgcaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
3061 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaa
//