LOCUS HSU79458 1691 bp mRNA linear HUM 01-FEB-1999
DEFINITION Human WW domain binding protein-2 mRNA, complete cds.
ACCESSION U79458
VERSION U79458.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1691)
AUTHORS Chen,H.I. and Sudol,M.
TITLE The WW domain of Yes-associated protein binds a proline-rich ligand
that differs from the consensus established for Src homology
3-binding modules
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 92 (17), 7819-7823 (1995)
PUBMED 7644498
REFERENCE 2 (bases 1 to 1691)
AUTHORS Chen,H.I., Einbond,A., Kwak,S.J., Linn,H., Kelly,J. and Sudol,M.
TITLE Characterization of the WW domain of Yes-associated protein and its
ligands
JOURNAL J. Biol. Chem. (1996) In press
REFERENCE 3 (bases 1 to 1691)
AUTHORS Chen,H.I., Einbond,A., Kwak,S.J. and Sudol,M.
TITLE Direct Submission
JOURNAL Submitted (22-NOV-1996) Laboratory of Molecular Oncology,
Rockefeller University, 1230 York Avenue, New York, NY 10021, USA
FEATURES Location/Qualifiers
source 1..1691
/db_xref="H-InvDB:HIT000221530"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="17"
/map="17q25"
CDS 26..832
/note="WBP-2; binds to the WW domain of Yes-associated
protein (YAP) through a proline-rich motif PPPPY (PY
motif) contained within the sequence."
/codon_start=1
/product="WW domain binding protein-2"
/protein_id="AAD10951.1"
/translation="MDGWGETMALNKNHSEGGGVIVNNTESILMSYDHVELTFNDMKN
VPEAFKGTKKGTVYLTPYRVIFLSKGKDAMQSFMMPFYLMKDCEIKQPVFGANYIKGT
VKAEAGGGWEGSASYKLTFTAGGAIEFGQRMLQVASQASRGEVPSGAYGYSYMPSGAY
VYPPPVANGMYPCPPGYPYPPPPPEFYPGPPMMDGAMGYVQPPPPPYPGPMEPPVSGP
DVPSTPAAEAKAAEAAASAYYNPGNPHNVYMPTSQPPPPPYYPPEDKKTQ"
BASE COUNT 324 a 582 c 434 g 351 t
ORIGIN
1 actagtggat ccgtcgacgg ccattatgga tggatgggga gagactatgg cgctcaacaa
61 gaatcactcg gagggcggcg gagtgatcgt caataacacc gagagcatcc taatgtccta
121 tgatcacgtg gaactcacat tcaatgacat gaagaacgtg ccagaagcct tcaaagggac
181 caagaaaggc actgtctacc ttacccctta ccgggtcatc tttctgtcca agggcaagga
241 tgccatgcag tccttcatga tgccatttta tctcatgaaa gactgtgaga tcaagcagcc
301 cgtatttggt gcaaactaca tcaagggaac agtgaaggcg gaagcgggag gtggctggga
361 aggctctgct tcctacaagt tgactttcac ggcagggggc gccattgagt tcggacagcg
421 gatgctccag gtggcatctc aagcctccag aggtgaagtc cccagtggag cctatggcta
481 ctcttacatg cccagcgggg cctatgtcta tcccccgcca gtcgccaatg gaatgtaccc
541 ctgccctcct ggctacccct atccaccgcc cccacctgag ttctatccag gaccccccat
601 gatggacggg gccatgggat acgtgcagcc cccaccaccg ccctaccctg ggcccatgga
661 acctccggtc agcggccccg atgtcccctc cactcctgca gccgaagcca aggccgcaga
721 agcagccgcc agcgcctatt acaacccagg caatcctcac aacgtctaca tgcccacgag
781 ccagccgccg ccacctccct actacccacc ggaagataag aagacccagt aggccctcct
841 gcctccctgc ctcccaccct catctctcta ccctacccct cccatcgggg ctgtgctggg
901 gcttggggag gggagggggc gccttgttct ccctccaggt ctgatcataa acaattacca
961 ggaactagca ttgtgggaca ttagggcccc cggcctcggg agaggtgccg cccagcttcc
1021 catgccagcc cggagcccac agtgctgccc agcgtacctc cctcaccgtc tggggctctt
1081 ctgggagcac ggagcatccc ctgttcctgt ttcacctctc agcttctccc ctcgaaggga
1141 ctctctggcc acctcctcca ccgcagtcca gctccctcag tctggcaccc actgctacac
1201 tcagcctcat gagccacttc agaccagcca ggtgtcttcc cgggccctgc cagaccctgc
1261 tcacattccc tctgctggtc tgtgctggtc tcagaaggcc accgcgcccg cattccactc
1321 agccagggtc cagctgcagc ccccgccacc cttccttccc ttccctgtcc tgggtcatgt
1381 tgttgccacc ctgtgtgact tttgaagctg taaaatgagc ttccagggct tgggtggcgt
1441 cggggcaggg ccgccgaggc tgggaggaag cccttctgcc ttttgctggt gtttctggaa
1501 tttgctttcc ctcacctctc acttccttct agaaggagct tcctgactgg aaccagagaa
1561 tgcatgtctg tccacttggt ggctgctggg tggggccggg aacaagggcc cctgaccctg
1621 tgtgctggcc gggacctgcc accagccccc cagcctgctt cttcccctta agcttatcga
1681 taccgtcgac c
//