LOCUS HSU78557 2732 bp mRNA linear HUM 27-NOV-1996
DEFINITION Human cisplatin resistance associated beta protein (hCRA beta)
mRNA, complete cds.
ACCESSION U78557
VERSION U78557.1
KEYWORDS Cisplatin; hCRA.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2732)
AUTHORS Tanimura,H., Ledakis,P. and Fojo,T.
TITLE Direct Submission
JOURNAL Submitted (15-NOV-1996) Medicine Branch, National Cancer Institute,
9000 Rockville Pike, Bethesda, MD 20892, USA
FEATURES Location/Qualifiers
source 1..2732
/db_xref="H-InvDB:HIT000221433"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_line="cisplatin resistant cell line A2780 E(80)
derived from A2780 cell line(human ovarian carcinoma)"
gene 1..2732
/gene="hCRA beta"
CDS 247..1005
/gene="hCRA beta"
/codon_start=1
/product="cisplatin resistance associated beta protein"
/protein_id="AAB36953.1"
/translation="MGSVQENRMPEPRSRQPSSCLASRCLPGEQILAWAPGVRKGLEP
ELSGTLICTNFRVTFQPCGWQWNQDTPLNSEYDFALVNIGRLEAVSGLSRVQLLRPGS
LHKFIPEEILIHGRDFRLLRVGFEAGGLEPQAFQVTMAIVQARAQSNQAQQYSGITLS
KAGQGSGSRKPPIPLMETAEDWETERKKQAARGWRVSTVNERFDVATRLRCFSSSLIV
SGSSSSSFQLILNSLSFSFLLFMTVSGFLTPLPS"
BASE COUNT 628 a 695 c 685 g 724 t
ORIGIN
1 cacacctttc caaggacccc caaactctgc tccgtgcacg tcaaatgctc ctttcccttg
61 tgtccaaccc cctacccctc tccctaacac ccctcttctc aacaagactc agcctctccc
121 cgaggtgggt gagcatcctt gaggtttccc acccttaact gctgtgtccc cggatggagc
181 cagagaaatg tggtgggggg gccggggcag agtttcaaca ttgcccccca gaaggaggag
241 ccagagatgg ggtctgtcca ggaaaacagg atgccggagc ccaggagtcg tcagcctagc
301 agttgcctgg cctccagatg cctcccaggg gagcagatcc tagcatgggc cccaggggtg
361 aggaagggcc tggaaccaga attgtctgga accctgatct gtaccaactt tagggtcacc
421 ttccagccct gtggatggca gtggaatcag gacactccct tgaacagtga atacgatttt
481 gccctggtca acattggacg attagaggct gtgagcggct tgtcccgagt ccagctcctc
541 cgtccagggt ccctgcataa atttatccct gaggagattc tgattcatgg ccgagacttc
601 cggctgctca gagttggttt tgaggctgga ggcctagagc ctcaggcttt tcaggtgacc
661 atggccattg tccaagccag agctcagagc aatcaagccc aacagtattc ggggataacc
721 ctgagcaagg ctggccaggg ttctggctcc agaaaaccac caattcctct catggagaca
781 gcggaagact gggagactga gcggaagaag caggcagcca gaggctggag ggtcagcacg
841 gtcaacgaga ggttcgacgt agccaccagg ctccggtgtt tctcctcttc cttgattgtg
901 tctggcagct cctccagcag tttccagctg attttgaatt ctctgagttt ttccttcttg
961 ctcttcatga cagtgtcagg gttcctgaca cccttacctt cctgagaaat accccctggg
1021 agcgcggaaa gcagagcgga caggtcagtg acttctattt ttgactcgtg tttttttttc
1081 cattgagatg tactctctga agtttggtct tgatttgttt tatgagaagt gaggtctgtg
1141 agtggggagg gggagattta ttctcatttt caggacgaga cttttgccct acatctttcc
1201 tagaataaga ggtgagaatc tcatgatttg tctctagatg tgggaggatt gtgtgtaacc
1261 atcctttttc ttgcttcctc tgtccagtta aactcctata cacaagtcta caccccagga
1321 tactccagcc tccagctggg aactctttta acctgcagct gtctgtctgg gactgggatt
1381 tacgttatag caatgcacag atactacaat tccagaatcc tggctatgac ccagaacact
1441 gtccagattc ctggctccct agaccacagc caagcttcat ggttcctgga ccccccagtt
1501 ttgtgtggct cttctctaga ggagcattga cccccctgaa tcagctctgt ccttggcggg
1561 acagtccttc cctgctggca gtctcttctc gttggctccc tcgacctgct atctcctctg
1621 aaagctggct gaccaggaat ggggtctccc ctcacattgg ggagcttgcc ctttacctcc
1681 agggctgctg ctgcctgggt atctgggacc ccagatcagg ctctggagac gctgctacct
1741 gaggggaagg cctgaggtcc aggtaagaag ggaaaataga ctgggagtgg gacaagggac
1801 ttgactctgc tgaaccagat gaacaggagc tggaaaggca aggagctgaa gcctctggga
1861 gtctgggaag tgaagttcta ctcctcttgg catcaaacaa ggtttgggag tgtaggaggt
1921 gcgggaaagt gcttgtggct tagattaagt ggaatttagg gcatagctga aaggggaaac
1981 agaattaaag acaccagaag tagcagagaa gcagggggcc agagctacaa cagtattctt
2041 ctctgttcct ctttgcctcc tccccagatg ggcctctcat ctcccacaat ctctggcctc
2101 caggatgagc tatcccatct tcaggagtta ttacggaaag gacaccaaga atatctcctg
2161 aggatcactc caagaaaaga gatccacata ccattctcaa tcccactgaa attgctggca
2221 ttctcaaagg cagggcagag ggggatctgg ggtagaggga gggttctgtc taatcttttt
2281 tttttctttt gtatctgcac ttgcagcctc agctttcata cttcagccct taagttcact
2341 aagaaggtct gagtttctgc tgcagatagt ggtgttaact gctccaactc ttgtcttgct
2401 tagtttctac aaatattttt gcttcttgtc atttgaagga ttaagaaaca aaaacaatcc
2461 agaaattgat cggttttttt aggccaatcc catcccttct ggataaccag atgttaaatc
2521 atgagatcag agatgctgtt catcagtccc aacaagatgg cctagaaatc gcattctcac
2581 ctcgccttgc tgctgcttta attccaagtt ctatttcttc ccttatagtt ttctatggga
2641 atgaggcgga tacaggaaac accctatctc ctctgtattt ttgtagtgga atttctattt
2701 aaggggctca ttaaagcata gtatttatac ac
//