LOCUS HSU78311 5256 bp mRNA linear HUM 08-OCT-1997
DEFINITION Human translation initiation factor 3 large subunit mRNA, complete
cds.
ACCESSION U78311
VERSION U78311.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5256)
AUTHORS Johnson,K.R., Merrick,W.C., Zoll,W.L. and Zhu,Y.
TITLE Identification of cDNA clones for the large subunit of eukaryotic
translation initiation factor 3. Comparison of homologues from
human, Nicotiana tabacum, Caenorhabditis elegans, and Saccharomyces
cerevisiae
JOURNAL J. Biol. Chem. 272 (11), 7106-7113 (1997)
PUBMED 9054404
REFERENCE 2 (bases 1 to 5256)
AUTHORS Zhu,Y. and Johnson,K.R.
TITLE Direct Submission
JOURNAL Submitted (14-NOV-1996) Biology, University of Toledo, 2801 W.
Bancroft St., Toledo, OH 43606, USA
FEATURES Location/Qualifiers
source 1..5256
/db_xref="H-InvDB:HIT000221422"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
CDS 114..4262
/codon_start=1
/product="translation initiation factor 3 large subunit"
/protein_id="AAB80695.1"
/translation="MPAYFQRPENALKRANEFLEVGKKQPALDVLYDVMKSKKHRTWQ
KIHEPIMLKYLELCVDLRKSHLAKEGLYQYKNICQQVNIKSLEDVVRAYLKMAEEKTE
AAKEESQQMVLDIEDLDNIQTPESVLLSAVSGEDTQDRTDRLLLTPWVKFLWESYRQC
LDLLRNNSRVERLYHDIAQQAFKFCLQYTRKAEFRKLCDNLRMHLSQIQRHHNQSTAI
NLNNPESQSMHLETRLVQLDSAISMELWQEAFKAVEDIHGLFSLSKKPPKPQLMANYY
NKVSTVFWKSGNALFHASTLHRLYHLSREMRKNLTQDEMQRMSTRVLLATLSIPITPE
RTDIARLLDMDGIIVEKQRRLATLLGLQAPPTRIGLINDMVRFNVLQYVVPEVKDLYN
WLEVEFNPLKLCERVTKVLNWVREQPEKEPELQQYVPQLQNNTILRLLQQVSQIYQSI
EFSRLTSLVPFVDAFQLERAIVDAARHCDLQVRIDHTSRTLSFGSDLNYATREDAPIG
PHLQSMPSEQIRNQLTAMSSVLAKALEVIKPAHILQEKEEQHQLAVTAYLKNSRKEHQ
RILARRQTIEERKERLESLNIQREKEELEQREAELQKVRKAEEERLRQEAKEREKERI
LQEHEQIKKKTVRERLEQIKKTELGAKAFKDIDIEDLEELDPDFIMAKQVEQLEKEKK
ELQERLKNQEKKIDYFERAKRLEEIPLIKSAYEEQRIKDMDLWEQQEEERITTMQLER
EKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQFEERLAEERHNRLEERKRQR
KEERRITYYREKEEEEQRRAEEQMLKEREERERAERAKREEELREYQERVKKLEEVER
KKRQRELEIEERERRREEERRLGDSSLSRKDSRWGDRDSEGTWRKGPEADSEWRRGPP
EKEWRRGEGRDEDRSHRRDEERPRRLGDDEDREPSLRPDDDRVPRRGMDDDRGPRRGP
EEDRFSRRGADDDRPSWRNTDDDRPPRRIADEDRGNWRHADDDRPPRRGLDEDRGSWR
TADEDRGPRRGMDDDRGPRRGGADDERSSWRNADDDRGPRRGLDDDRGPRRGMDDDRG
PRRGMDDDRGPRRGMDDDRGPRRGLDDDRGPWRNADDDRIPRRGAEDDRGPWRNMDDD
RLSRRADDDRFPRRGDDSRPGPWRPLVKPGGWREKEKAREESWGPPRESRPSEEREWD
REKERDRDNQDREENDKDPERERDRERDVDREDRFRRPRDEGGWRRGPAEESSSWRDS
SRRDDRDRDDRRRERDDRRDLRERRDLRDDRDRRGPPLRSEREEVSSWRRADDRKDDR
VEERDPPRRVPPPALSRDRERDRDREREGEKEKASWRAEKDRESLRRTKNETDEDGWT
TVRR"
BASE COUNT 1693 a 965 c 1374 g 1224 t
ORIGIN
1 ggcgactgct ggcgaggcgc gtgggacctt acgctggttc cccttcgtct cctctcccgg
61 cccgggccac tagagagttc gctgacgccg ggtgagctga gcctgccgcc aagatgccgg
121 cctattttca gaggccggaa aatgccctca aacgcgccaa cgaatttctt gaggttggca
181 aaaagcagcc tgctctggat gttctttatg atgttatgaa aagtaaaaaa catagaacat
241 ggcaaaagat acacgaacca attatgttga aatacttgga actttgcgtg gatcttcgca
301 agagccactt ggcaaaggag gggttatacc agtataagaa catttgtcaa caggtgaaca
361 taaaatctct ggaggatgtt gttagggcat atttgaaaat ggcagaggaa aaaactgaag
421 ctgctaaaga agaatctcag cagatggtct tagatataga ggatctagat aatattcaaa
481 ctcctgagag tgttctccta agtgctgtaa gtggtgaaga cactcaggat cgtactgaca
541 gattactttt aactccatgg gttaaattcc tgtgggagtc ttacaggcag tgtttggacc
601 ttcttagaaa caattctaga gtagagcgcc tgtaccatga tattgcccag caagctttca
661 aattctgcct ccaatacacg cgtaaggctg aattccgtaa actgtgtgac aatttgagaa
721 tgcacttatc gcagattcag cgccaccata accaaagtac ggcaatcaat cttaataatc
781 cagagagcca gtccatgcat ttggaaacca gacttgttca gctggacagt gctatcagca
841 tggaattgtg gcaggaagca ttcaaagctg tggaagatat tcacgggcta ttctccttgt
901 ctaaaaaacc acctaaacct cagttgatgg caaattacta taacaaagtc tcaactgtgt
961 tttggaaatc tggaaatgct ctttttcatg catctacact ccatcgtctt taccatctct
1021 ctagagaaat gagaaagaat ctcacacaag acgagatgca aagaatgtct actagagtcc
1081 ttttagccac tctttccatc cctattactc ctgagcgtac ggatattgct cgacttctgg
1141 atatggatgg cattatagtt gaaaaacagc gtcgccttgc aacactacta ggtcttcaag
1201 ccccaccgac acgaattggc cttattaatg atatggtcag atttaatgta ctacaatatg
1261 ttgtcccaga agtgaaagac ctttacaatt ggcttgaagt agaatttaac ccattaaaac
1321 tctgtgagcg agtcacaaag gttctaaatt gggttaggga acaacctgaa aaggaaccgg
1381 aattgcagca gtatgtgcca caactgcaaa acaacaccat cctccgcctt ctgcagcagg
1441 tgtcacagat ttatcagagc attgagtttt ctcgtttgac ttctttggtt ccttttgttg
1501 atgctttcca actggaacgg gccatagtag atgcagccag gcattgcgac ttgcaggttc
1561 gtattgatca cacttctcgg accctgagtt ttggatctga tttgaattat gctactcgag
1621 aagatgctcc gattggtcct catttgcaaa gcatgccttc agagcagata agaaaccagc
1681 tgacagccat gtcctcagta cttgcaaaag cacttgaagt cattaaacca gctcatatac
1741 tgcaagagaa agaagaacag catcagttgg ctgtcactgc ataccttaaa aattcacgaa
1801 aagagcacca gcggatcctg gctcgccgcc agacaattga ggagagaaaa gagcgccttg
1861 agagtctgaa tattcagcgt gagaaagaag aattggaaca gagggaagct gaactccaga
1921 aagtgcggaa ggctgaggaa gagaggctgc gccaggaagc aaaggagaga gagaaggagc
1981 gtatcttaca ggaacatgaa caaatcaaaa agaaaactgt ccgagagcgt ttggagcaga
2041 tcaagaaaac agaactgggt gccaaagcat tcaaagatat tgatattgaa gaccttgagg
2101 aattggatcc agattttatc atggctaaac aggttgaaca actggagaaa gaaaagaaag
2161 aacttcaaga acgcctaaag aatcaagaaa agaagattga ctattttgaa agagccaaac
2221 gtttggaaga aattcctttg ataaagagcg cttacgagga acagagaatt aaagacatgg
2281 atctgtggga gcaacaagag gaagaaagaa ttactacaat gcagctagaa cgtgaaaagg
2341 ctcttgaaca taagaatcga atgtcacgaa tgcttgaaga cagagattta ttcgtaatgc
2401 gactcaaagc tgcacggcag tctgtttatg aggaaaaact taaacagttt gaagagcgat
2461 tagcagaaga aaggcataat cgattggaag aacggaaaag gcagcgtaaa gaagaacgca
2521 ggataacata ctatagagaa aaagaagagg aggagcagag aagggcagaa gaacaaatgc
2581 taaaagagcg ggaagagaga gagcgcgccg aacgagcaaa acgcgaggaa gagctacgag
2641 agtatcagga gcgggtgaag aaattagaag aagtggaaag gaaaaaacgc caaagggagt
2701 tggaaattga agaacgagaa cggcgtagag aggaagagag aagacttggc gatagttccc
2761 tttctagaaa ggactctcgt tggggagata gagattcaga aggcacctgg agaaaaggac
2821 ctgaagcaga ttctgagtgg agaagaggcc cgccagagaa ggagtggaga cgtggagaag
2881 ggcgagatga ggacaggtct catagaagag atgaagagcg gccccggcgt ctgggggatg
2941 atgaagatag agagccctct cttagaccag acgatgatcg ggttccccgg cgtggcatgg
3001 atgatgacag aggccctaga cgtggtcctg aggaagatag gttctctcgt cgtggggcag
3061 acgatgaccg gccttcctgg cgtaacacag atgatgacag gcctcccaga cgaattgccg
3121 atgaagacag gggaaactgg cgtcatgcgg atgatgacag accacctaga cgaggactgg
3181 atgaggacag aggaagctgg cgaacagctg atgaggacag aggaccaaga cgtgggatgg
3241 atgatgaccg ggggccgagg cgaggaggcg ctgatgatga gcgatcatcc tggcgtaatg
3301 ctgatgatga ccggggtccc aggcgagggt tggatgatga tcggggtccc aggcgaggca
3361 tggatgatga ccggggtccc aggcgaggca tggatgatga ccggggtccc aggcgaggca
3421 tggatgatga ccggggtccc aggcgagggt tggatgatga tcgaggacct tggaggaacg
3481 ccgatgatga cagaattccc aggcgtggtg cagaggatga caggggccct tggagaaaca
3541 tggatgatga tcgcctttca agacgtgctg atgatgatcg gtttcccaga cggggtgatg
3601 actcaagacc tggtccttgg agaccattag tcaagccagg tggatggaga gagaaagaaa
3661 aagccagaga ggagagctgg ggtccacctc gagaatcaag gccatcagaa gaacgtgaat
3721 gggacagaga aaaagaaagg gacagagata atcaagatcg ggaggagaat gacaaggacc
3781 ctgagagaga aagggacaga gagagagatg tggatcgaga ggatcgcttc agaagaccta
3841 gggatgaagg tggctggaga agaggaccag ctgaggaatc ttcaagctgg agagactcaa
3901 gtcgccggga cgatagggat agggatgacc gtcgccgtga gagggatgac cggcgtgatc
3961 taagagaaag acgagatcta agagacgaca gggaccgaag aggacctcca ctcagatcag
4021 aacgtgaaga agtaagttct tggagacgtg ctgatgacag gaaagatgac cgggtggaag
4081 agcgggaccc tcctcgtcga gttcctcccc cagctctttc aagagaccga gaaagagacc
4141 gagaccgaga aagagaaggt gaaaaagaga aggcctcatg gagagctgag aaagataggg
4201 aatctctccg tcgtactaaa aatgagactg atgaagatgg atggaccaca gtacgacgtt
4261 aagtctcaag ataatggatt taaactggtg tcttaaatag gtttgatcac attcaaggat
4321 tattatactt gtgcttcaac caatctaaat tggattcttt aatgttgttt caccataaca
4381 caaaaagcat gaacttgtat taatcctata taatagattg atcatgcacc atatccacag
4441 gaggttggaa aaaccatgcc attttctgga atttaagggt gttgcattat ttcatcaatc
4501 atttgttgac aaaaaagaaa aactaaaaaa taaatttaaa atgtgaacct tcaggtattg
4561 agtaacacct ttatcttggt atagaactga taccattttt tgattttgaa atatctgata
4621 ataatttgga atgaagtaag gttctgttaa aatatatttg aagacccttt aaagcagtga
4681 atctgaaaca attttcacac ccttaagtgg ttgatacgta cctattttag gtattttgag
4741 gtatttacca taaactaaat ttagaaattt tttagattca cttgaagtaa acattacaaa
4801 cattggatac ggtggggttt tctttagatt ttacttgaga gaaggtgagt acaaagcaat
4861 ttgcagttgt tgtaatgaca agattactgc gcaagtgtga atccaaacag tatagctttt
4921 aaattttaaa gcatttggta aattatcgct gagttttttt ctgttgccaa tagcaaactg
4981 cttttccatt aatggagaat tcatgccttt caagcatttt aaatatgaca atatttataa
5041 atgtatggtt tggaggaatc gtttaaattc tctttcctaa ttttctttct tttgaagata
5101 gattctttca acaagtaatt tgtagtaatg actgtgttga cttcaatttt ggagcgcagt
5161 agctatgtta aagatgaact atttggtctc attgaagcca acacagaact tgctgctgtg
5221 ttttttcttc agtgataaat aaaatactta cagaaa
//