LOCUS HSU78294 2685 bp mRNA linear HUM 27-JUN-1997
DEFINITION Homo sapiens 15S-lipoxygenase mRNA, complete cds.
ACCESSION U78294
VERSION U78294.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2685)
AUTHORS Brash,A.R., Boeglin,W.E. and Chang,M.S.
TITLE Discovery of a second 15S-lipoxygenase in humans
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 94 (12), 6148-6152 (1997)
PUBMED 9177185
REFERENCE 2 (bases 1 to 2685)
AUTHORS Brash,A.R., Boeglin,W.E. and Chang,M.S.
TITLE Direct Submission
JOURNAL Submitted (14-NOV-1996) Clinical Pharmacology, Vanderbilt
University, MRB1 510 23rd Ave S. at Pierce, Nashville, TN
37232-6602, USA
FEATURES Location/Qualifiers
source 1..2685
/db_xref="H-InvDB:HIT000221417"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/tissue_type="skin, prostate, cornea, lung"
CDS 72..2102
/codon_start=1
/product="15S-lipoxygenase"
/protein_id="AAB61706.1"
/translation="MAEFRVRVSTGEAFGAGTWDKVSVSIVGTRGESPPLPLDNLGKE
FTAGAEEDFQVTLPEDVGRVLLLRVHKAPPVLPLLGPLAPDAWFCRWFQLTPPRGGHL
LFPCYQWLEGAGTLVLQEGTAKVSWADHHPVLQQQRQEELQARQEMYQWKAYNPGWPH
CLDEKTVEDLELNIKYSTAKNANFYLQAGSAFAEMKIKGLLDRKGLWRSLNEMKRIFN
FRRTPAAEHAFEHWQEDAFFASQFLNGLNPVLIRRCHYLPKNFPVTDAMVASLLGPGT
SLQAELEKGSLFLVDHGILSGIQTNVINGKPQFSAAPMTLLYQSPGCGPLLPLAIQLS
QTPGPNSPIFLPTDDKWDWLLAKTWVRNAEFSFHEALTHLLHSHLLPEVFTLATLRQL
PHCHPLFKLLIPHTRYTLHINTLARELLIVPGQVVDRSTGIGIEGFSELIQRNMKQLN
YSLLCLPEDIRTRGVEDIPGYYYRDDGMQIWGAVERFVSEIIGIYYPSDESVQDDREL
QAWVREIFSKGFLNQESSGIPSSLETREALVQYVTMVIFTCSAKHAAVSAGQFDSCAW
MPNLPPSMQLPPPTSKGLATCEGFIATLPPVNATCDVILALWLLSKEPGDQRPLGTYP
DEHFTEEAPRRSIATFQSRLAQISRGIQERNRGLVLPYTYLDPPLIENSVSI"
BASE COUNT 625 a 829 c 721 g 510 t
ORIGIN
1 caggcgtgtc ccagggggag ccccgctctg cagccctgtg cgccgtagag agctggactt
61 aggctggcag catggccgag ttcagggtca gggtgtccac cggagaagcc ttcggggctg
121 gcacatggga caaagtgtct gtcagcatcg tggggacccg gggagagagc cccccactgc
181 ccctggacaa tctcggcaag gagttcactg cgggcgctga ggaggacttc caggtgacgc
241 tcccggagga cgtaggccga gtgctgctgc tgcgcgtgca caaggcgccc ccagtgctgc
301 ccctgctggg gcccctggcc ccggatgcct ggttctgccg ctggttccag ctgacaccgc
361 cgcggggcgg ccacctcctc ttcccctgct accagtggct ggagggggcg gggaccctgg
421 tgctgcagga gggtacagcc aaggtgtcct gggcagacca ccaccctgtg ctccagcaac
481 agcgccagga ggagcttcag gcccggcagg agatgtacca gtggaaggct tacaacccag
541 gttggcctca ctgcctggat gaaaagacag tggaagactt ggagctcaat atcaaatact
601 ccacagccaa gaatgccaac ttttatctac aagctggctc tgcttttgca gagatgaaaa
661 tcaaggggtt gctggaccgc aaggggctct ggaggagtct gaatgagatg aaaaggatct
721 tcaacttccg gaggacccca gcagctgagc acgcatttga gcactggcag gaggatgcct
781 tcttcgcctc ccagttcctg aatggtctca accctgtcct gatccgccgc tgtcactacc
841 tcccaaagaa cttccccgtc actgatgcca tggtggcctc attgttgggt cctgggacca
901 gcttgcaggc tgagctagag aagggctccc tgttcttggt ggatcacggc atcctctctg
961 gcatccagac caatgtcatt aatgggaagc cgcagttctc tgcggcccca atgaccctgc
1021 tataccagag cccaggctgc gggccgctgc tgcctctcgc catccagctc agccagaccc
1081 ccggcccaaa cagccccatc ttcctgccca ctgatgacaa gtgggactgg ttgctggcca
1141 agacctgggt gcgcaatgcc gagttctcct tccatgaggc cctcacgcac ctgctgcact
1201 cacatctgct gcctgaggtc ttcaccctgg ctaccctgcg tcagctgccc cactgccacc
1261 ctctcttcaa gctgctgatc ccgcacaccc gatacaccct gcacatcaac acactcgccc
1321 gggagctgct tatcgtgcca gggcaggtgg tggacaggtc cacaggcatc ggcattgaag
1381 gcttctctga gttgatacag aggaacatga agcagctgaa ctattctctc ctgtgtctgc
1441 ctgaggatat ccggacccga ggagttgaag acatcccagg ctactactac cgtgatgatg
1501 ggatgcagat ttggggtgca gtggaacgct ttgtctctga aatcatcggt atctactacc
1561 caagtgatga gtctgtccaa gatgacagag agctccaggc ctgggtcaga gagatcttct
1621 ccaagggctt cctaaaccag gagagctcag gtatcccttc ctcactggag acccgggaag
1681 ccctggtgca gtatgtcacc atggtgatat tcacctgctc agccaagcat gcggctgtca
1741 gtgcagggca gtttgactcc tgtgcttgga tgcccaacct gccacccagc atgcagctgc
1801 caccacccac ctccaaaggc ctggcaacat gcgagggctt catagccacc ctcccacctg
1861 tcaatgccac atgtgatgtc atccttgctc tctggttgct gagcaaggag cctggagacc
1921 aaaggcccct gggcacctat ccggatgagc acttcacaga ggaggcccct cggcggagca
1981 tcgccacctt ccagagccgc ctggcccaga tctcgagggg catccaggag cggaaccggg
2041 gcctggtgct gccctacacc tacctagacc ctcccctcat cgagaacagc gtctccatct
2101 aaatcccagg ggaacacagg cccagatgac atccctttga ccacatcgct ctaggataac
2161 tggcacccag agaaaaggac tcctcagaaa aaacaggccc ccatgtgcct ctcctgggac
2221 aaccagactc tgtaactcac ccccaccacc atacacacac acaaaaacag aaacaaaatc
2281 aaaacagaga aagcagaaaa tctaccaaga acagagtctc aggacagaac cactgagtct
2341 tttggaggct ccaagcctca aagtgcccgc agagcccacc ttgagggttt tgctagttgg
2401 ttttgttttg cgtttacagc cgtgggggga agcacataat cccgccccag ggcccactag
2461 catccactga ttggacctta tggtcaccca actcaaggac agccaccaag aagtggctgc
2521 caaagagact gggcgcagtg gctcatgccc ataatcccag cactttggga gatggaggcg
2581 ggaaaatcat ttgaggtcag aagttcaagg ccagcctgga cgacatagcg agactccacc
2641 tctaccaaaa aataaaaatt aaaaaacaaa aaaaaaaaaa aaaaa
//