LOCUS HSU78170 2236 bp mRNA linear HUM 05-FEB-1999
DEFINITION Homo sapiens calcium- and diacylglycerol-regulated guanine
nucleotide exchange factor I (CalDAG-GEFI) mRNA, complete cds.
ACCESSION U78170
VERSION U78170.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2236)
AUTHORS Kawasaki,H., Springett,G.M., Toki,S., Canales,J.J., Harlan,P.,
Blumenstiel,J.P., Chen,E.J., Bany,I.A., Mochizuki,N., Ashbacher,A.,
Matsuda,M., Housman,D.E. and Graybiel,A.M.
TITLE A Rap guanine nucleotide exchange factor enriched highly in the
basal ganglia
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 95 (22), 13278-13283 (1998)
PUBMED 9789079
REFERENCE 2 (bases 1 to 2236)
AUTHORS Kawasaki,H., Housman,D.E. and Graybiel,A.M.
TITLE Direct Submission
JOURNAL Submitted (14-NOV-1996) Center for Cancer Research/Department of
Brain and Cognitive Sciences, Massachusetts Institute of
Technology, 77 Massachusetts Avenue, E17-540, Cambridge, MA 02135,
USA
REFERENCE 3 (bases 1 to 2236)
AUTHORS Kawasaki,H., Housman,D.E. and Graybiel,A.M.
TITLE Direct Submission
JOURNAL Submitted (05-FEB-1999) Center for Cancer Research/Department of
Brain and Cognitive Sciences, Massachusetts Institute of
Technology, 77 Massachusetts Avenue, E17-540, Cambridge, MA 02135,
USA
REMARK Sequence update by submitter
COMMENT On Feb 5, 1999 this sequence version replaced gi:4079652.
FEATURES Location/Qualifiers
source 1..2236
/db_xref="H-InvDB:HIT000221413"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
gene 1..2236
/gene="CalDAG-GEFI"
CDS 161..1990
/gene="CalDAG-GEFI"
/note="contains EF hand and DAG binding domain"
/codon_start=1
/product="calcium- and diacylglycerol-regulated guanine
nucleotide exchange factor I"
/protein_id="AAD12741.1"
/translation="MAGTLDLDKGCTVEELLRGCIEAFDDSGKVRDPQLVRMFLMMHP
WYIPSSQLAAKLLHIYQQSRKDNSNSLQVKTCHLVRYWISAFPAEFDLNPELAEQIKE
LKALLDQEGNRRHSSLIDIDSVPTYKWKRQVTQRNPVGQKKRKMSLLFDHLEPMELAE
HLTYLEYRSFCKILFQDYHSFVTHGCTVDNPVLERFISLFNSVSQWVQLMILSKPTAP
QRALVITHFVHVAEKLLQLQNFNTLMAVVGGLSHSSISRLKETHSHVSPETIKLWEGL
TELVTATGNYGNYRRRLAACVGFRFPILGVHLKDLVALQLALPDWLDPARTRLNGAKM
KQLFSILEELAMVTSLRPPVQANPDLLSLLTVSLDQYQTEDELYQLSLQREPRSKSSP
TSPTSCTPPPRPPVLEEWTSAAKPKLDQALVVEHIEKMVESVFRNFDVDGDGHISQEE
FQIIRGNFPYLSAFGDLDQNQDGCISREEMVSYFLRSSSVLGGRMGFVHNFQESNSLR
PVACRHCKALILGIYKQGLKCRACGVNCHKQCKDRLSVECRRRAQSVSLEGSAPSPSP
MHSHHHRAFSFSLPRPGRRGSRPPEIREEEVQTVEDGVFDIHL"
BASE COUNT 471 a 670 c 676 g 419 t
ORIGIN
1 ggggactcaa ggctggcctg gctcaagtga acagcacgtc caggaggcga cctcgtccgc
61 gggtttgcat tctggggtgg acgagctggg ggttcggtcc gagcccggtg ggaggctccc
121 ggagcgcagc ctgggcccag cccaccccgc gccggcggcc atggcaggca ccctggacct
181 ggacaagggc tgcacggtgg aggagctgct ccgcgggtgc atcgaagcct tcgatgactc
241 cgggaaggtg cgggacccgc agctggtgcg catgttcctc atgatgcacc cctggtacat
301 cccctcctct cagctggcgg ccaagctgct ccacatctac caacaatccc ggaaggacaa
361 ctccaattcc ctgcaggtga aaacgtgcca cctggtcagg tactggatct ccgccttccc
421 agcggagttt gacttgaacc cggagttggc tgagcagatc aaggagctga aggctctgct
481 agaccaagaa gggaaccgac ggcacagcag cctaatcgac atagacagcg tccctaccta
541 caagtggaag cggcaggtga ctcagcggaa ccctgtggga cagaaaaagc gcaagatgtc
601 cctgttgttt gaccacctgg agcccatgga gctggcggag catctcacct acttggagta
661 tcgctccttc tgcaagatcc tgtttcagga ctatcacagt ttcgtgactc atggctgcac
721 tgtggacaac cccgtcctgg agcggttcat ctccctcttc aacagcgtct cacagtgggt
781 gcagctcatg atcctcagca aacccacagc cccgcagcgg gccctggtca tcacacactt
841 tgtccacgtg gcggagaagc tgctacagct gcagaacttc aacacgctga tggcagtggt
901 cgggggcctg agccacagct ccatctcccg cctcaaggag acccacagcc acgttagccc
961 tgagaccatc aagctctggg agggtctcac ggaactagtg acggcgacag gcaactatgg
1021 caactaccgg cgtcggctgg cagcctgtgt gggcttccgc ttcccgatcc tgggtgtgca
1081 cctcaaggac ctggtggccc tgcagctggc actgcctgac tggctggacc cagcccggac
1141 ccggctcaac ggggccaaga tgaagcagct ctttagcatc ctggaggagc tggccatggt
1201 gaccagcctg cggccaccag tacaggccaa ccccgacctg ctgagcctgc tcacggtgtc
1261 tctggatcag tatcagacgg aggatgagct gtaccagctg tccctgcagc gggagccgcg
1321 ctccaagtct tcgccaacca gccccacgag ttgcacccca ccaccccggc ccccggtatt
1381 ggaggagtgg acctcggctg ccaaacccaa gctggatcag gccctcgtgg tggagcacat
1441 cgagaagatg gtggagtctg tgttccggaa ctttgacgtc gatggggatg gccacatctc
1501 acaggaagaa ttccagatca tccgtgggaa cttcccttac ctcagcgcct ttggggacct
1561 cgaccagaac caggatggct gcatcagcag ggaggagatg gtttcctatt tcctgcgctc
1621 cagctctgtg ttgggggggc gcatgggctt cgtacacaac ttccaggaga gcaactcctt
1681 gcgccccgtc gcctgccgcc actgcaaagc cctgatcctg ggcatctaca agcagggcct
1741 caaatgccga gcctgtggag tgaactgcca caagcagtgc aaggatcgcc tgtcagttga
1801 gtgtcggcgc agggcccaga gtgtgagcct ggaggggtct gcaccctcac cctcacccat
1861 gcacagccac catcaccgcg ccttcagctt ctctctgccc cgccctggca ggcgaggctc
1921 caggcctcca gagatccgtg aggaggaggt acagacggtg gaggatgggg tgtttgacat
1981 ccacttgtaa tagatgctgt ggttggatca aggactcatt cctgccttgg agaaaatact
2041 tcaaccagag cagggagcct gggggtgtcg gggcaggagg ctggggatgg gggtgggata
2101 tgagggtggc atgcagctga gggcagggcc agggctggtg tccctaaggt tgtacagact
2161 cttgtgaata tttgtatttt ccagatggaa taaaaaggcc cgtgtaatta accttcaaaa
2221 aaaaaaaaaa aaaaaa
//