LOCUS HSU77970 2880 bp mRNA linear HUM 12-FEB-1997
DEFINITION Human neuronal PAS2 (NPAS2) mRNA, complete cds.
ACCESSION U77970
VERSION U77970.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2880)
AUTHORS Zhou,Y.D., Barnard,M., Tian,H., Li,X., Ring,H.Z., Francke,U.,
Shelton,J., Richardson,J., Russell,D.W. and McKnight,S.L.
TITLE Molecular characterization of two mammalian bHLH-PAS domain
proteins selectively expressed in the central nervous system
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 94 (2), 713-718 (1997)
PUBMED 9012850
REFERENCE 2 (bases 1 to 2880)
AUTHORS Zhou,Y.-D., Barnard,M., Tian,H., Li,X., Ring,H.Z., Francke,U.,
Shelton,J., Richardson,J., Russell,D.W. and McKnight,S.L.
TITLE Direct Submission
JOURNAL Submitted (11-NOV-1996) Biochemistry, UT Southwestern, 5323 Harry
Hines Blvd., Dallas, TX 75235, USA
FEATURES Location/Qualifiers
source 1..2880
/db_xref="H-InvDB:HIT000221400"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_line="HeLa"
gene 1..2880
/gene="NPAS2"
CDS 287..2761
/gene="NPAS2"
/note="a member of the bHLH-PAS family; longest predicted
reading frame; two of two transcripts, see GenBank
Accession Number U77968"
/codon_start=1
/product="neuronal PAS2"
/protein_id="AAB47250.1"
/translation="MDEDEKDRAKRASRNKSEKKRRDQFNVLIKELSSMLPGNTRKMD
KTTVLEKVIGFLQKHNEVSAQTEICDIQQDWKPSFLSNEEFTQLMLEALDGFIIAVTT
DGSIIYVSDSITPLLGHLPSDVMDQNLLNFLPEQEHSEVYKILSSHMLVTDSPSPEYL
KSDSDLEFYCHLLRGSLNPKEFPTYEYIKFVGNFRSYNNVPSPSCNGFDNTLSRPCRV
PLGKEVCFIATVRLATPQFLKEMCIVDEPLEEFTSRHSLEWKFLFLDHRAPPIIGYLP
FEVLGTSGYDYYHIDDLELLARCHQHLMQFGTGKSCCYRFLTKGQQWIWLQTHYYITY
HQWNSKPEFIVCTHSVVSYADVRVERRQELALEDPPSEALHSSALKDKGSSLEPRQHF
NALDVGASGLNTSHSPSASSRSSHKSSHTAMSEPTSTPTKLMAEASTPALPRSATLPQ
ELPVPGLSQAATMPAPLPSPLSCDLTQQLLPQTVLQSTPAPMAQFSAQFSMFQTIKDQ
LEQRTRILQANIRWQQEELHKIQEQLCLVQDSNVQMFLQQPAVSLSFSSTQRPEAQQQ
LQQRSAAVTQPQLGAGPQLPGQISSAQVTSQHLLRESSVISTQGPKPMRSSQLMQSSG
RSGSSLVSPFSSATAALPPSLNLTTPASTSQDASQCQPSPDFSHDRQLRLLLSQPIQP
MMPGSCDARQPSEVSRTGRQVKYAQSQTVFQNPDAHPANSSSAPMPVLLMGQAVLHPS
FPASQPSPLQPAQARQQPPQHYLQVQAPTSLHSEQQDSLLLSTYSQQPGTLGYPQPPP
AQPQPLRPPRRVSSLSESSGLQQPPR"
BASE COUNT 686 a 937 c 723 g 534 t
ORIGIN
1 gtttgccgcg cgagcagccg gcctctcgca ggagccgagg gacccgcgcg gctgcggccc
61 aggagcggcg gccgcggagc ccggagaccc gcagccgcgg cggcggcggc ggcggcggca
121 gcagctagag cagcgcctcc cgccgccgcc cgggaggagc tcgccgcgcc cgctcgccgc
181 ctcgtctccc agcggcggcg ggaggcgcgt ctccccggcc cagtccgcgc ccggccccgc
241 gggaccgctc cggcccgctc cgaggaaaaa ctgcatagaa aatctaatgg atgaagatga
301 gaaagacaga gccaagagag cttctcgaaa caagtctgag aagaagcgtc gggaccagtt
361 caatgttctc atcaaagagc tcagttccat gctccctggc aacacgcgga aaatggacaa
421 aaccaccgtg ttggaaaagg tcatcggatt tttgcagaaa cacaatgaag tctcagcgca
481 aacggaaatc tgtgacattc agcaagactg gaagccttca ttcctcagta atgaagaatt
541 cacccagctg atgttggagg cattagatgg cttcattatc gcagtgacaa cagacggcag
601 catcatctat gtctctgaca gtatcacgcc tctccttggg catttaccgt cggatgtcat
661 ggatcagaat ttgttaaatt tcctcccaga acaagaacat tcagaagttt ataaaatcct
721 ttcttcccat atgcttgtga cggattcccc ctccccagaa tacttaaaat ctgacagcga
781 tttagagttt tattgccatc ttctcagagg cagcttgaac ccaaaggaat ttccaactta
841 tgaatacata aaatttgtag gaaattttcg ctcttacaac aatgtgccta gcccctcctg
901 taatggtttt gacaacaccc tttcaagacc ttgccgggta ccactaggaa aggaggtttg
961 cttcattgcc accgttcgtc tggcaacacc acaattctta aaggaaatgt gcatagttga
1021 cgaaccttta gaggaattca cttcaaggca tagcttggaa tggaaatttt tatttctgga
1081 tcacagagca cctccaatca taggatacct gccttttgaa gtgctgggaa cctcaggcta
1141 tgactactac cacattgatg acctggagct cctggccagg tgtcaccagc acctgatgca
1201 gtttggcaca gggaagtcgt gttgctaccg gtttctgacc aaaggtcagc agtggatctg
1261 gctgcagact cactactaca tcacctacca tcagtggaac tccaagcccg agttcatcgt
1321 gtgcacacac tcggtggtca gttacgcaga tgtccgggtg gaaaggaggc aggagctggc
1381 tctggaagac ccgccatccg aggccctcca ctcctcagca ctaaaggaca agggctcaag
1441 cctggaacct cggcagcact ttaacgcact cgacgtgggt gcctcgggcc ttaataccag
1501 tcattcgcca tcggcgtcct caagaagttc ccacaaatcc tcgcacacag ccatgtcaga
1561 acccacctcc actcccacca agctgatggc agaggccagc accccggctt tgccaagatc
1621 agccaccctg ccccaagagt tacctgtccc cgggctcagc caggcagcca ccatgccggc
1681 ccctctgcct tccccattgt cctgcgacct cacacagcag ctcctgcctc agaccgttct
1741 gcagagcacg cccgctccca tggcacagtt ttcggcacag ttcagcatgt tccagaccat
1801 caaagaccag ctagagcagc ggacgcggat cctgcaggcc aatatccggt ggcaacagga
1861 agagctccac aagatccagg agcagctctg cctggtccag gactccaacg tccagatgtt
1921 cctgcagcag ccagctgtat ccctgagctt cagcagcacc cagcgacctg aggctcagca
1981 gcagctacag caaaggtcag ctgcagtgac tcagccccag ctcggggcgg gcccccaact
2041 tccagggcag atctcctctg cccaggtcac aagccagcac ctgctcagag aatcaagtgt
2101 gatatcaacc caaggtccaa agccaatgag aagctcacag ctaatgcaga gcagcggccg
2161 ctctggaagc agcctagtgt ccccgttcag cagcgccaca gctgcgctcc cgccaagtct
2221 gaatctgacc acacctgctt ccacctccca ggatgccagc cagtgccagc ccagcccaga
2281 cttcagccat gatcggcagc tcaggctgtt gctgagccag cccatccagc ccatgatgcc
2341 cgggtcctgt gacgcaaggc agccctcgga agtcagcagg acgggacggc aagtcaagta
2401 cgcccagagc cagaccgtgt ttcaaaatcc agacgcacac cccgccaaca gcagcagcgc
2461 cccgatgccc gtcctgctga tggggcaggc ggtgctccac cccagcttcc ctgcctccca
2521 accatcgccc ctgcagcctg cacaggcccg gcagcagcca ccgcagcact acctgcaggt
2581 acaggcacca acctctttgc acagtgagca gcaggactcg ctacttctct ccacctactc
2641 acaacagcca gggaccctgg gctaccccca accaccccca gcacagcccc agcccctacg
2701 tcctccccga agggtcagca gtctgtctga gtcgtcaggc ctccagcagc cgccccgata
2761 atgccccggc actgaagtcg ggacacaatc agctttaacc aatggatgag gggggtggcc
2821 acaggagatg gggagaggag tctgaactaa acccctggct tttgtgcaca ctgcatacgt
//