LOCUS HSU77968 1904 bp mRNA linear HUM 12-FEB-1997
DEFINITION Human neuronal PAS1 (NPAS1) mRNA, complete cds.
ACCESSION U77968
VERSION U77968.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1904)
AUTHORS Zhou,Y.D., Barnard,M., Tian,H., Li,X., Ring,H.Z., Francke,U.,
Shelton,J., Richardson,J., Russell,D.W. and McKnight,S.L.
TITLE Molecular characterization of two mammalian bHLH-PAS domain
proteins selectively expressed in the central nervous system
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 94 (2), 713-718 (1997)
PUBMED 9012850
REFERENCE 2 (bases 1 to 1904)
AUTHORS Zhou,Y.-D., Barnard,M., Tian,H., Li,X., Ring,H.Z., Francke,U.,
Shelton,J., Richardson,J., Russell,D.W. and McKnight,S.L.
TITLE Direct Submission
JOURNAL Submitted (11-NOV-1996) Biochemistry, UT Southwestern, 5323 Harry
Hines Blvd., Dallas, TX 75235, USA
FEATURES Location/Qualifiers
source 1..1904
/db_xref="H-InvDB:HIT000221399"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/tissue_type="brain"
/clone_lib="Stratagene, Catalog No. 936206"
/dev_stage="fetus"
gene 1..1904
/gene="NPAS1"
CDS 25..1797
/gene="NPAS1"
/note="member of the bHLH-PAS family; one of two
transcripts, see GenBank Accession Number U77970"
/codon_start=1
/product="neuronal PAS1"
/protein_id="AAB47248.1"
/translation="MAAPYPGSGGGSEVKCVGGRGASVPWDFLPGLMVKAPSGPCLQA
QRKEKSRNAARSRRGKENLEFFELAKLLPLPGAISIQLDKASIVRLSVTYLRLRRFAA
LGAPPWGLRAAGPPAGLAPGRRGPAALVSEVFEQHLGGHILQSLDGFVFALNQEGKFL
YISETVSIYLGLSQVEMTGSSVFDYIHPGDHSEVLEQLGLRTTTPGPPTPSSVSSSSS
SSSSLADTPEIEASLTKVPPSSLVQERSFFVRMKSTLTKRGLHVKASGYKVIHVTGRL
RAHALGLVALGHTLPPAPLAELPLHGHMIVFRLSLGLTILACESRVSDHMDLGPSELV
GRSCYQFVHGQDATRIRQSHVDLLDKGQVMTGYYRWLQRAGGFVWLQSVATVAGSGKS
PGEHHVLWVSHVLSQAEGGQTPLDAFQLPASVACEEASSPGPEPTEPEPPTEGKQAVP
AENEAPQTQGKRIKVEPGPRETKGSEDSGDEDPSSHPATPRPEFTSVIRAGVLKQDPV
RPWGLAPPGDPPPTLLHAGFLPPVVRGLCTPGTIRYGPAELGLVYPHLQRLGPGPALP
EAFYPPLGLPYPGPAGTRLPRKGD"
BASE COUNT 304 a 685 c 614 g 301 t
ORIGIN
1 cccgcctgag cgagcccccc ggagatggcg gccccctatc ccggcagtgg cggcggaagc
61 gaggtcaaat gcgtgggagg ccgcggcgcc agcgtcccct gggactttct acccgggctg
121 atggtcaagg cgccgtccgg accgtgcctg caggcgcagc gcaaggagaa gtcccggaac
181 gcggcgcgct cgcggcgcgg gaaggagaac ctggagttct tcgagctggc caagcttctc
241 ccgctgcccg gcgccatctc catccagctg gacaaggctt ccatcgtgcg cctcagcgtc
301 acctacctcc gcctgcgccg gttcgccgcg ctgggggcgc cgccctgggg gctgagagcc
361 gcggggccgc cagctggcct cgccccaggc cgccgcggcc ccgcagcgct ggtctccgaa
421 gtcttcgagc agcacctggg aggtcacatc ttgcagtccc tggatggctt tgtgttcgcc
481 ttgaaccagg aaggaaaatt cctctacatc tcagagacag tctccatcta tctgggtctc
541 tcacaggtgg agatgacggg cagcagcgtc ttcgactaca ttcaccctgg ggaccactca
601 gaggtgctgg agcaactggg gctgcggacg acgacgcccg gccccccaac cccgtcctcc
661 gtctcctctt cctcctcctc ttcctcttcg cttgcagata cccccgagat cgaggccagc
721 ctcaccaagg tgcccccctc ctccctggtc caggagcgct ccttctttgt ccgcatgaaa
781 tccacgctca ccaagagggg gctgcacgtc aaggcctcag ggtacaaggt catccacgtg
841 actgggcgcc ttcgggccca cgccctgggc cttgtggccc tcgggcacac gttgcccccg
901 gcccccctgg ctgagctgcc actccatgga cacatgatcg tcttccgtct cagcctgggt
961 ctcaccatcc ttgcttgtga gagcagagtc agcgaccaca tggacctggg gccctcagag
1021 ctggtgggcc gcagctgcta ccagtttgtc cacggacaag acgccacgag gatccgccag
1081 agccacgtgg acttgctgga caagggtcag gtgatgactg gttactaccg ttggctgcag
1141 cgtgccgggg gcttcgtgtg gctgcagtct gtggccacag tggctgggag cgggaagagc
1201 cccggggagc accatgtgct ttgggtcagc cacgtgctca gccaagccga gggtggccaa
1261 actcctttgg atgccttcca gcttccagcc agcgtggcct gtgaggaggc atccagcccg
1321 gggccagagc ccacagagcc ggagcctccg acggaaggga agcaggctgt cccagcggag
1381 aacgaggccc cccagaccca gggcaaacgc atcaaagtgg agcccggccc gagggaaacc
1441 aaaggttccg aggacagtgg cgacgaggat ccctccagcc acccggccac accgaggccc
1501 gagttcacct ctgtcatccg ggcaggggtc ctgaagcagg atccggtgcg gccatggggc
1561 ctggcgcctc ccggggaccc cccgcccacc ctcctgcacg cgggcttcct gccgccggtg
1621 gtgcggggcc tgtgcacacc cggcaccatc cgctacggcc ccgcggagct gggcctggtg
1681 tacccgcacc tgcagaggct gggtccgggc cccgcgctcc cggaggcctt ttacccgccc
1741 ctgggcctgc cctacccggg gcccgcgggc accaggctgc cgcggaaggg ggactgagga
1801 ctggcagagc tgccggcgcc ggaccctgcg acaaccgggg tcccccagga cagtaggccc
1861 ggctctgccc gtagccctga gaattaaacg ccggctctcc ctgc
//