LOCUS HSU76992 2672 bp mRNA linear HUM 13-NOV-1996
DEFINITION Human Tat-SF1 mRNA, complete cds.
ACCESSION U76992
VERSION U76992.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2672)
AUTHORS Zhou,Q. and Sharp,P.A.
TITLE Tat-SF1: cofactor for stimulation of transcriptional elongation by
HIV-1 Tat
JOURNAL Science 274 (5287), 605-610 (1996)
PUBMED 8849451
REFERENCE 2 (bases 1 to 2672)
AUTHORS Zhou,Q. and Sharp,P.A.
TITLE Direct Submission
JOURNAL Submitted (31-OCT-1996) Center for Cancer Research, Massachusetts
Institute of Technology, 40 Ames St., Cambridge, MA 02139, USA
FEATURES Location/Qualifiers
source 1..2672
/db_xref="H-InvDB:HIT000221323"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/cell_line="HL60"
gene 1..2672
/gene="Tat-SF1"
CDS 58..2322
/gene="Tat-SF1"
/function="cofactor required for Tat activation of HIV-1
transcription"
/note="similar to EWS and FUS/TLS77"
/codon_start=1
/product="Tat-SF1"
/protein_id="AAB18823.1"
/translation="MSGTNLDGNDEFDEQLRMQELYGDGKDGDTQTDAGGEPDSLGQQ
PTDTPYEWDLDKKAWFPKITEDFIATYQANYGFSNDGASSSTANVEDVHARTAEEPPQ
EKAPEPTDARKKGEKRKAESGWFHVEEDRNTNVYVSGLPPDITVDEFIQLMSKFGIIM
RDPQTEEFKVKLYKDNQGNLKGDGLCCYLKRESVELALKLLDEDEIRGYKLHVEVAKF
QLKGEYDASKKKKKCKDYKKKLSMQQKQLDWRPERRAGPSRMRHERVVIIKNMFHPMD
FEDDPLVLNEIREDLRVECSKFGQIRKLLLFDRHPDGVASVSFRDPEEADYCIQTLDG
RWFGGRQITAQAWDGTTDYQVEETSREREERLRGWEAFLNAPEANRGLSVQILSLLRK
AGPSRARHFSEHPSTSKMNAQETATGMAFEEPIDEKKFEKTEDGGEFEEGASENNAKE
SSPEKEAEEGCPEKESEEGCPKRGFEGSCSQKESEEGNPVRGSEEDSPKKESKKKTLK
NDCEENGLAKESEDDLNKESEEEVGPTKESEEDDSEKESDEDCSEKQSEDGSEREFEE
NGLEKDLDEEGSEKELHENVLDKELEENDSENSEFEDDGSEKVLDEEGSEREFDEDSD
EKEEEEDTYEKVFDDESDEKEDEEYADEKGLEAADKKAEEGDADEKLFEESDDKEDED
ADGKEVEDADEKLFEDDDSNEKLFDEEEDSSEKLFDDSDERGTLGGFGSVEEGPLSTG
SSFILSSDDDDDDI"
BASE COUNT 898 a 420 c 711 g 643 t
ORIGIN
1 agcgtcattt cggcctctta gttcttctga accctgctcc tgagctaggt aggaaacatg
61 agcggcacca acttggatgg gaacgatgag tttgatgagc agttgcgaat gcaagaattg
121 tacggagacg gcaaggatgg tgacacccag accgatgccg gcggagaacc cgattctctc
181 gggcagcagc cgacggacac tccctacgag tgggacctgg acaaaaaggc ttggttcccc
241 aagattactg aagatttcat tgctacatat caggccaatt atggcttctc taacgatggc
301 gcatctagtt ctaccgcaaa tgttgaagat gtccatgcta ggactgcaga ggaacctcca
361 caagaaaaag ccccggaacc cactgatgcc agaaagaagg gagaaaaaag aaaggctgag
421 tcaggatggt ttcatgttga agaagacaga aatacaaatg tatacgtgtc tggtttgcct
481 ccagatatta cagtggatga atttatacaa cttatgtcca agtttggcat tattatgaga
541 gatcctcaga cagaagaatt taaggtcaaa ctttacaaag ataatcaagg aaatcttaaa
601 ggagacggtc tttgctgtta tttgaaaaga gaatctgtgg aacttgcatt aaaacttttg
661 gatgaagatg aaattagagg ctacaaatta catgttgagg tggcaaagtt tcaactgaag
721 ggagaatatg atgcctcaaa gaagaagaag aagtgcaaag actataagaa gaagctgtct
781 atgcaacaaa agcagttgga ttggagacct gagaggcgag ccggaccatc ccggatgcgc
841 catgagcgag ttgtcatcat caagaatatg tttcatccta tggattttga ggatgatccg
901 ttggtgctga atgagatcag agaagacctt cgagtagagt gttcgaagtt tggacaaatt
961 aggaaactcc ttctctttga taggcaccca gatggtgtgg cctctgtgtc ctttcgggat
1021 ccagaggaag ctgattattg tattcagact ctcgatggaa gatggtttgg tggccgtcaa
1081 atcactgccc aggcatggga tgggactaca gattatcagg tggaggaaac ctcaagagaa
1141 agggaggaaa ggctgagagg atgggaggct ttcctcaatg ctcctgaggc caacagaggc
1201 cttagcgttc agattctgtc tctgcttcga aaggcagggc cttctagagc aaggcatttt
1261 tcagagcacc ccagcacatc taaaatgaat gctcaagaaa ctgcaactgg aatggcattt
1321 gaagaaccta tagatgagaa gaagtttgaa aagacagaag atgggggaga atttgaagaa
1381 ggtgcttctg aaaacaatgc taaggaaagt agccccgaaa aagaggctga agaaggctgc
1441 cctgaaaaag aatctgaaga gggctgcccc aaaagagggt ttgaaggcag ctgctcccaa
1501 aaagagtctg aagaaggcaa tcccgtaaga ggatctgaag aggatagtcc taaaaaagag
1561 tctaaaaaga agacactcaa aaatgattgt gaagagaatg gccttgcaaa ggaatctgaa
1621 gatgacctca acaaggagtc tgaagaggag gttggcccca caaaagagtc cgaagaagat
1681 gactcagaga aagagtctga tgaagactgc tctgaaaaac agtctgaaga tggctccgaa
1741 agagaatttg aagaaaatgg tctcgagaaa gatttggacg aggaaggttc tgaaaaggag
1801 cttcatgaaa atgttcttga caaagagtta gaagaaaatg actctgaaaa ctccgaattt
1861 gaagatgacg gctctgaaaa agtgttagat gaggaaggct ctgagagaga gtttgacgaa
1921 gattcagatg aaaaggaaga agaggaggat acatatgaaa aagtatttga tgatgagtct
1981 gatgagaaag aggatgaaga atatgcagat gaaaaggggc ttgaagctgc tgataaaaag
2041 gcggaagaag gtgatgcaga tgaaaagctg tttgaagagt cagatgacaa ggaagatgaa
2101 gatgcagatg gaaaggaagt tgaagatgct gacgaaaagt tgttcgaaga tgatgattcc
2161 aatgagaagt tgtttgatga ggaggaagat tccagtgaga agttgtttga cgattctgat
2221 gagaggggga ctttgggtgg ttttgggagt gttgaagaag ggcccctatc cactggcagc
2281 agctttattc tcagtagcga tgatgatgac gatgatattt aatcccttaa acttgctttt
2341 tagggagagt cctccatcta catttgcctg tgcttcaggg taattactag tagtgttaca
2401 tgaacatgtg catagtggta ggatgccatc agattaaagc attgaagtgt ttcattgtta
2461 cctgtaccta atggttttaa atatatgtta attgattgtt tagttaaaat gtcatagtta
2521 caatgcaagt aaactggata cttgttcttt tgtcagattt gttaaatgca tgcagaataa
2581 tatttttaag agtattgatt gaagtttgtg atattcatca ataaaaatga gttgataata
2641 tgcagaaact gaaaaaaaaa aaaaaaaaaa aa
//