LOCUS HSU76702 2500 bp mRNA linear HUM 17-OCT-1998
DEFINITION Homo sapiens follistatin-related protein FLRG (FLRG) mRNA, complete
cds.
ACCESSION U76702
VERSION U76702.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2500)
AUTHORS Hayette,S., Gadoux,M., Martel,S., Bertrand,S., Tigaud,I.,
Magaud,J.P. and Rimokh,R.
TITLE FLRG (follistatin-related gene), a new target of chromosomal
rearrangement in malignant blood disorders
JOURNAL Oncogene 16 (22), 2949-2954 (1998)
PUBMED 9671416
REFERENCE 2 (bases 1 to 2500)
AUTHORS Rimokh,R.
TITLE Direct Submission
JOURNAL Submitted (30-OCT-1996) INSERM U453, Centre Leon Berard, 28 rue
Laennec, Lyon 69373, France
COMMENT Rimokh, R. Blood 83, 31-36, 1994.
FEATURES Location/Qualifiers
source 1..2500
/db_xref="H-InvDB:HIT000221318"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="19"
/map="19p13"
/tissue_type="placenta"
/dev_stage="term"
/note="cloning of a t(11;19)(q13;p13) chromosomal
breakpoint showed that the cyclin D1 gene (localized on
11q13) is juxtaposed to a chromosome 19 coding region
FLRG"
gene 1..2500
/gene="FLRG"
CDS 8..799
/gene="FLRG"
/note="secreted glycoprotein; similar to members of
follistatin-module-protein family"
/codon_start=1
/product="follistatin-related protein FLRG"
/protein_id="AAC64321.1"
/translation="MRPGAPGPLWPLPWGALAWAVGFVSSMGSGNPAPGGVCWLQQGQ
EATCSLVLQTDVTRAECCASGNIDTAWSNLTHPGNKINLLGFLGLVHCLPCKDSCDGV
ECGPGKACRMLGGRPRCECAPDCSGLPARLQVCGSDGATYRDECELRAARCRGHPDLS
VMYRGRCRKSCEHVVCPRPQSCVVDQTGSAHCVVCRAAPCPVPSSPGQELCGNNNVTY
ISSCHMRQATCFLGRSIGVRHAGSCAGTPEEPPGGESAEEEENFV"
repeat_region 1213..1524
/gene="FLRG"
/note="24-nucleotide repeat; new VNTR-type polymorphism;
present in FLRG 3' UTR"
/rpt_type=tandem
BASE COUNT 419 a 790 c 806 g 485 t
ORIGIN
1 gttcgccatg cgtcccgggg cgccagggcc actctggcct ctgccctggg gggccctggc
61 ttgggccgtg ggcttcgtga gctccatggg ctcggggaac cccgcgcccg gtggtgtttg
121 ctggctccag cagggccagg aggccacctg cagcctggtg ctccagactg atgtcacccg
181 ggccgagtgc tgtgcctccg gcaacattga caccgcctgg tccaacctca cccacccggg
241 gaacaagatc aacctcctcg gcttcttggg ccttgtccac tgccttccct gcaaagattc
301 gtgcgacggc gtggagtgcg gcccgggcaa ggcgtgccgc atgctggggg gccgcccgcg
361 ctgcgagtgc gcgcccgact gctcggggct cccggcgcgg ctgcaggtct gcggctcaga
421 cggcgccacc taccgcgacg agtgcgagct gcgcgccgcg cgctgccgcg gccacccgga
481 cctgagcgtc atgtaccggg gccgctgccg caagtcctgt gagcacgtgg tgtgcccgcg
541 gccacagtcg tgcgtcgtgg accagacggg cagcgcccac tgcgtggtgt gtcgagcggc
601 gccctgccct gtgccctcca gccccggcca ggagctttgc ggcaacaaca acgtcaccta
661 catctcctcg tgccacatgc gccaggccac ctgcttcctg ggccgctcca tcggcgtgcg
721 ccacgcgggc agctgcgcag gcacccctga ggagccgcca ggtggtgagt ctgcagaaga
781 ggaagagaac ttcgtgtgag cctgcaggac aggcctgggc ctggtgcccg aggcccccca
841 tcatcccctg ttatttattg ccacagcaga gtctaattta tatgccacgg acactcctta
901 gagcccggat tcggaccact tggggatccc agaacctccc tgacgatatc ctggaaggac
961 tgaggaaggg aggcctgggg gccggctggt gggtgggata gacctgcgtt ccggacactg
1021 agcgcctgat ttagggccct tctctaggat gccccagccc ctaccctaag acctattgcc
1081 ggggaggatt ccacacttcc gctcctttgg ggataaacct attaattatt gctactatca
1141 agagggctgg gcattctctg ctggtaattc ctgaagaggc atgactgctt ttctcagccc
1201 caagcctcta gtctgggtgt gtacggaggg tctagcctgg gtgtgtacgg agggtctagc
1261 ctgggtgagt acggagggtc tagcctgggt gagtacggag ggtctagcct gggtgagtac
1321 ggagagtcta gcctgggtgt gtatggagga tctagcctgg gtgagtatgg agggtctagc
1381 ctgggtgagt atggagggtc tagcctgggt gtgtatggag ggtctagcct gggtgagtat
1441 ggagggtcta gcctgggtgt gtatggaggg tctagcctgg gtgagtatgg agggtctagc
1501 ctgggtgtgt acggagggtc tagtctgagt gcgtgtgggg acctcagaac actgtgacct
1561 tagcccagca agccaggccc ttcatgaagg ccaagaaggc tgccaccatt ccctgccagc
1621 ccaagaactc cagcttcccc actgcctctg tgtgcccctt tgcgtcctgt gaaggccatt
1681 gagaaatgcc cagtgtgccc cctgggaaag ggcacggcct gtgctcctga cacgggctgt
1741 gcttggccac agaaccaccc agcgtctccc ctgctgctgt ccacgtcagt tcatgaggca
1801 acgtcgcgtg gtctcagacg tggagcagcc agcggcagct cagagcaggg cactgtgtcc
1861 ggcggagcca agtccactct gggggagctc tggcggggac cacgggccac tgctcaccca
1921 ctggccccga ggggggtgta gacgccaaga ctcacgcatg tgtgacatcc ggagtcctgg
1981 agccgggtgt cccagtggca ccactaggtg cctgctgcct ccacagtggg gttcacaccc
2041 agggctcctt ggtcccccac aacctgcccc ggccaggcct gcagacccag actccagcca
2101 gacctgcctc acccaccaat gcagccgggg ctggcgacac cagccaggtg ctggtcttgg
2161 gccagttctc ccacgacggc tcaccctccc ctccatctgc gttgatgctc agaatcgcct
2221 acctgtgcct gcgtgtaaac cacagcctca gaccagctat ggggagagga caacacggag
2281 gatatccagc ttccccggtc tggggtgagg agtgtgggga gcttgggcat cctcctccag
2341 cctcctccag cccccaggca gtgccttacc tgtggtgccc agaaaagtgc ccctaggttg
2401 gtgggtctac aggagcctca gccaggcagc ccaccccacc ctggggccct gcctcaccaa
2461 ggaaataaag actcaaagaa gccttttttt tttttttttt
//