LOCUS HSU76638 2530 bp mRNA linear HUM 10-DEC-1996
DEFINITION Human BRCA1-associated RING domain protein (BARD1) mRNA, complete
cds.
ACCESSION U76638
VERSION U76638.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2530)
AUTHORS Wu,L.C., Wang,Z.W., Tsan,J.T., Spillman,M.A., Phung,A., Xu,X.L.,
Yang,M.C., Hwang,L.Y., Bowcock,A.M. and Baer,R.
TITLE Identification of a RING protein that can interact in vivo with the
BRCA1 gene product
JOURNAL Nat. Genet. 14 (4), 430-440 (1996)
PUBMED 8944023
REFERENCE 2 (bases 1 to 2530)
AUTHORS Wu,L.C., Wang,Z.W., Tsan,J.T., Spillman,M.A., Phung,A., Xu,X.L.,
Yang,M.-C.W., Hwang,L.-Y., Bowcock,A.M. and Baer,R.
TITLE Direct Submission
JOURNAL Submitted (29-OCT-1996) Microbiology, U.T. Southwestern Medical
Center, 6000 Harry Hines Boulevard, Dallas, TX 75235-9140, USA
FEATURES Location/Qualifiers
source 1..2530
/db_xref="H-InvDB:HIT000221303"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="2"
/map="2q"
/note="A composite sequence derived from two overlapping
cDNA clones (B202 and B230) of BARD1 mRNA"
gene 1..2530
/gene="BARD1"
CDS 74..2407
/gene="BARD1"
/codon_start=1
/product="BRCA1-associated RING domain protein"
/protein_id="AAB38316.1"
/translation="MPDNRQPRNRQPRIRSGNEPRSAPAMEPDGRGAWAHSRAALDRL
EKLLRCSRCTNILREPVCLGGCEHIFCSNCVSDCIGTGCPVCYTPAWIQDLKINRQLD
SMIQLCSKLRNLLHDNELSDLKEDKPRKSLFNDAGNKKNSIKMWFSPRSKKVRYVVSK
ASVQTQPAIKKDASAQQDSYEFVSPSPPADVSERAKKASARSGKKQKKKTLAEINQKW
NLEAEKEDGEFDSKEESKQKLVSFCSQPSVISSPQINGEIDLLASGSLTESECFGSLT
EVSLPLAEQIESPDTKSRNEVVTPEKVCKNYLTSKKSLPLENNGKRGHHNRLSSPISK
RCRTSILSTSGDFVKQTVPSENIPLPECSSPPSCKRKVGGTSGRKNSNMSDEFISLSP
GTPPSTLSSSSYRQVMSSPSAMKLLPNMAVKRNHRGETLLHIASIKGDIPSVEYLLQN
GSDPNVKDHAGWTPLHEACNHGHLKVVELLLQHKALVNTTGYQNDSPLHDAAKNGHVD
IVKLLLSYGASRNAVNIFGLRPVDYTDDESMKSLLLLPEKNESSSASHCSVMNTGQRR
DGPLVLIGSGLSSEQQKMLSELAVILKAKKYTEFDSTVTHVVVPGDAVQSTLKCMLGI
LNGCWILKFEWVKACLRRKVCEQEEKYEIPEGPRRSRLNREQLLPKLFDGCYFYLWGT
FKHHPKDNLIKLVTAGGGQILSRKPKPDSDVTQTINTVAYHARPDSDQRFCTQYIIYE
DLCNYHPERVRQGKVWKAPSSWFIDCVMSFELLPLDS"
BASE COUNT 762 a 522 c 587 g 659 t
ORIGIN
1 cagcttccct gtggtttccc gaggcttcct tgcttcccgc tctgcgagga gcctttcatc
61 cgaaggcggg acgatgccgg ataatcggca gccgaggaac cggcagccga ggatccgctc
121 cgggaacgag cctcgttccg cgcccgccat ggaaccggat ggtcgcggtg cctgggccca
181 cagtcgcgcc gcgctcgacc gcctggagaa gctgctgcgc tgctcgcgtt gtactaacat
241 tctgagagag cctgtgtgtt taggaggatg tgagcacatc ttctgtagta attgtgtaag
301 tgactgcatt ggaactggat gtccagtgtg ttacaccccg gcctggatac aagacttgaa
361 gataaataga caactggaca gcatgattca actttgtagt aagcttcgaa atttgctaca
421 tgacaatgag ctgtcagatt tgaaagaaga taaacctagg aaaagtttgt ttaatgatgc
481 aggaaacaag aagaattcaa ttaaaatgtg gtttagccct cgaagtaaga aagtcagata
541 tgttgtgagt aaagcttcag tgcaaaccca gcctgcaata aaaaaagatg caagtgctca
601 gcaagactca tatgaatttg tttccccaag tcctcctgca gatgtttctg agagggctaa
661 aaaggcttct gcaagatctg gaaaaaagca aaaaaagaaa actttagctg aaatcaacca
721 aaaatggaat ttagaggcag aaaaagaaga tggtgaattt gactccaaag aggaatctaa
781 gcaaaagctg gtatccttct gtagccaacc atctgttatc tccagtcctc agataaatgg
841 tgaaatagac ttactagcaa gtggctcctt gacagaatct gaatgttttg gaagtttaac
901 tgaagtctct ttaccattgg ctgagcaaat agagtctcca gacactaaga gcaggaatga
961 agtagtgact cctgagaagg tctgcaaaaa ttatcttaca tctaagaaat ctttgccatt
1021 agaaaataat ggaaaacgtg gccatcacaa tagactttcc agtcccattt ctaagagatg
1081 tagaaccagc attctgagca ccagtggaga ttttgttaag caaaccgtgc cctcagaaaa
1141 tataccattg cctgaatgtt cttcaccacc ttcatgcaaa cgtaaagttg gtggtacatc
1201 agggaggaaa aacagtaaca tgtccgatga attcattagt ctttcaccag gtacaccacc
1261 ttctacatta agtagttcaa gttacaggca agtgatgtct agtccctcag caatgaagct
1321 gttgcccaat atggctgtga aaagaaatca tagaggagag actttgctcc atattgcttc
1381 tattaagggc gacatacctt ctgttgaata ccttttacaa aatggaagtg atccaaatgt
1441 taaagaccat gctggatgga caccattgca tgaagcttgc aatcatgggc acctgaaggt
1501 agtggaatta ttgctccagc ataaggcatt ggtgaacacc accgggtatc aaaatgactc
1561 accacttcac gatgcagcca agaatgggca cgtggatata gtcaagctgt tactttccta
1621 tggagcctcc agaaatgctg ttaatatatt tggtctgcgg cctgtcgatt atacagatga
1681 tgaaagtatg aaatcgctat tgctgctacc agagaagaat gaatcatcct cagctagcca
1741 ctgctcagta atgaacactg ggcagcgtag ggatggacct cttgtactta taggcagtgg
1801 gctgtcttca gaacaacaga aaatgctcag tgagcttgca gtaattctta aggctaaaaa
1861 atatactgag tttgacagta cagtaactca tgttgttgtt cctggtgatg cagttcaaag
1921 taccttgaag tgtatgcttg ggattctcaa tggatgctgg attctaaaat ttgaatgggt
1981 aaaagcatgt ctacgaagaa aagtatgtga acaggaagaa aagtatgaaa ttcctgaagg
2041 tccacgcaga agcaggctca acagagaaca gctgttgcca aagctgtttg atggatgcta
2101 cttctatttg tggggaacct tcaaacacca tccaaaggac aaccttatta agctcgtcac
2161 tgcaggtggg ggccagatcc tcagtagaaa gcccaagcca gacagtgacg tgactcagac
2221 catcaataca gtcgcatacc atgcgagacc cgattctgat cagcgcttct gcacacagta
2281 tatcatctat gaagatttgt gtaattatca cccagagagg gttcggcagg gcaaagtctg
2341 gaaggctcct tcgagctggt ttatagactg tgtgatgtcc tttgagttgc ttcctcttga
2401 cagctgaata ttataccaga tgaacatttc aaattgaatt tgcacggttt gtgagagccc
2461 agtcattgta ctgtttttaa tgttcacatt tttacaaata ggtagagtca ttcatatttg
2521 tctttgaatc
//