LOCUS HSU76420 3785 bp mRNA linear HUM 25-APR-1997
DEFINITION Human dsRNA adenosine deaminase DRADA2a (DRADA2a) mRNA, complete
cds.
ACCESSION U76420
VERSION U76420.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3785)
AUTHORS Lai,F., Chen,C.X., Carter,K.C. and Nishikura,K.
TITLE Editing of glutamate receptor B subunit ion channel RNAs by four
alternatively spliced DRADA2 double-stranded RNA adenosine
deaminases
JOURNAL Mol. Cell. Biol. 17 (5), 2413-2424 (1997)
PUBMED 9111310
REFERENCE 2 (bases 1 to 3785)
AUTHORS Nishikura,K.
TITLE Direct Submission
JOURNAL Submitted (28-OCT-1996) Room 256, The Wistar Institute, 3601 Spruce
Street, Philadelphia, PA 19104, USA
FEATURES Location/Qualifiers
source 1..3785
/db_xref="H-InvDB:HIT000221294"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/chromosome="21"
/map="21q22.3"
gene 1..3785
/gene="DRADA2a"
CDS 414..2519
/gene="DRADA2a"
/function="RNA editing enzyme"
/note="alternatively spliced"
/codon_start=1
/product="dsRNA adenosine deaminase DRADA2a"
/protein_id="AAC51240.1"
/translation="MDIEDEENMSSSSTDVKENRNLDNVSPKDGSTPGPGEGSQLSNG
GGGGPGRKRPLEEGSNGHSKYRLKKRRKTPGPVLPKNALMQLNEIKPGLQYTLLSQTG
PVHAPLFVMSVEVNGQVFEGSGPTKKKAKLHAAEKALRSFVQFPNASEAHLAMGRTLS
VNTDFTSDQADFPDTLFNGFETPDKAEPPFYVGSNGDDSFSSSGDLSLSASPVPASLA
QPPLPVLPPFPPPSGKNPVMILNELRPGLKYDFLSESGESHAKSFVMSVVVDGQFFEG
SGRNKKLAKARAAQSALAAIFNLHLDQTPSRQPIPSEGLQLHLPQVLADAVSRLVLGK
FGDLTDNFSSPHARRKVLAGVVMTTGTDVKDAKVISVSTGTKCINGEYMSDRGLALND
CHAEIISRRSLLRFLYTQLELYLNNKDDQKRSIFQKSERGGFRLKENVQFHLYISTSP
CGDARIFSPHEPILEEPADRHPNRKARGQLRTKIESGEGTIPVRSNASIQTWDGVLQG
ERLLTMSCSDKIARWNVVGIQGSLLSIFVEPIYFSSIILGSLYHGDHLSRAMYQRISN
IEDLPPLYTLNKPLLSGISNAEARQPGKAPNFSVNWTVGDSAIEVINATTGKDELGRA
SRLCKHALYCRWMRVHGKVPSHLLRSKITKPNVYHESKLAAKEYQAAKARLFTAFIKA
GLGAWVEKPTEQDQFSLTP"
BASE COUNT 900 a 1013 c 1060 g 812 t
ORIGIN
1 gcggcggcgg cggcggcggc ggcagcggcg gccaagcggc caggttggcg gccggggctc
61 cgggccgcgc gaggccacgg ccacgccgcg ccgctgcgca caaccaacga ggcagagcgc
121 cgcccggcgc gagactgcgg ccgaagcgtg gggcgcgcgt gcggaggacc aggcgcggcg
181 cggctgcggc tgagagtgga gcctttcagg ctggcatgga gagcttaagg ggcaactgaa
241 ggagacacac tggccaagcg cggagttctg cttacttcag tcctgctgag atactctctc
301 agtccgctcg caccgaagga agctgccttg ggatcagagc agacataaag ctagaaaaat
361 ttcaagacag aaacagtctc cgccagtcaa gaaaccctca aaagtatttt gccatggata
421 tagaagatga agaaaacatg agttccagca gcactgatgt gaaggaaaac cgcaatctgg
481 acaacgtgtc ccccaaggat ggcagcacac ctgggcctgg cgagggctct cagctctcca
541 atgggggtgg tggtggcccc ggcagaaagc ggcccctgga ggagggcagc aatggccact
601 ccaagtaccg cctgaagaaa aggaggaaaa caccagggcc cgtcctcccc aagaacgccc
661 tgatgcagct gaatgagatc aagcctggtt tgcagtacac actcctgtcc cagactgggc
721 ccgtgcacgc gcctttgttt gtcatgtctg tggaggtgaa tggccaggtt tttgagggct
781 ctggtcccac aaagaaaaag gcaaaactcc atgctgctga gaaggccttg aggtctttcg
841 ttcagtttcc taatgcctct gaggcccacc tggccatggg gaggaccctg tctgtcaaca
901 cggacttcac atctgaccag gccgacttcc ctgacacgct cttcaatggt tttgaaactc
961 ctgacaaggc ggagcctccc ttttacgtgg gctccaatgg ggatgactcc ttcagttcca
1021 gcggggacct cagcttgtct gcttccccgg tgcctgccag cctagcccag cctcctctcc
1081 ctgtcttacc accattccca cccccgagtg ggaagaatcc cgtgatgatc ttgaacgaac
1141 tgcgcccagg actcaagtat gacttcctct ccgagagcgg ggagagccat gccaagagct
1201 tcgtcatgtc tgtggtcgtg gatggtcagt tctttgaagg ctcggggaga aacaagaagc
1261 ttgccaaggc ccgggctgcg cagtctgccc tggccgccat ttttaacttg cacttggatc
1321 agacgccatc tcgccagcct attcccagtg agggtcttca gctgcattta ccgcaggttt
1381 tagctgacgc tgtctcacgc ctggtcctgg gtaagtttgg tgacctgacc gacaacttct
1441 cctcccctca cgctcgcaga aaagtgctgg ctggagtcgt catgacaaca ggcacagatg
1501 ttaaagatgc caaggtgata agtgtttcta caggaacaaa atgtattaat ggtgaataca
1561 tgagtgatcg tggccttgca ttaaatgact gccatgcaga aataatatct cggagatcct
1621 tgctcagatt tctttataca caacttgagc tttacttaaa taacaaagat gatcaaaaaa
1681 gatccatctt tcagaaatca gagcgagggg ggtttaggct gaaggagaat gtccagtttc
1741 atctgtacat cagcacctct ccctgtggag atgccagaat cttctcacca catgagccaa
1801 tcctggaaga accagcagat agacacccaa atcgtaaagc aagaggacag ctacggacca
1861 aaatagagtc tggtgagggg acgattccag tgcgctccaa tgcgagcatc caaacgtggg
1921 acggggtgct gcaaggggag cggctgctca ccatgtcctg cagtgacaag attgcacgct
1981 ggaacgtggt gggcatccag ggatccctgc tcagcatttt cgtggagccc atttacttct
2041 cgagcatcat cctgggcagc ctttaccacg gggaccacct ttccagggcc atgtaccagc
2101 ggatctccaa catagaggac ctgccacctc tctacaccct caacaagcct ttgctcagtg
2161 gcatcagcaa tgcagaagca cggcagccag ggaaggcccc caacttcagt gtcaactgga
2221 cggtaggcga ctccgctatt gaggtcatca acgccacgac tgggaaggat gagctgggcc
2281 gcgcgtcccg cctgtgtaag cacgcgttgt actgtcgctg gatgcgtgtg cacggcaagg
2341 ttccctccca cttactacgc tccaagatta ccaagcccaa cgtgtaccat gagtccaagc
2401 tggcggcaaa ggagtaccag gccgccaagg cgcgtctgtt cacagccttc atcaaggcgg
2461 ggctgggggc ctgggtggag aagcccaccg agcaggacca gttctcactc acgccctgac
2521 ccgggcagac atgatggggg gtgcaggggg ctgtgggcat ccagcgtcat cctccagaac
2581 ctcacatctg aactgggggc aggtgcatac cttggggagg gagtaggggg acacggggga
2641 ccaccaggtg tccacggttg tccccagcat ctcacatcag acctggggca ggtgcgcagt
2701 gtggggaggg gatggggtgc gtcagggccc agcatcgccg cctggcatct ctctgccgca
2761 gcatttcccc ttctgaaccg tccagtgact gctttcaatc tcggtttacg tttagaaatt
2821 gagttctact gagtagggct tccttaagtt taggaaaata gaaattactt tgtgtgaaat
2881 tcttgaataa ataatttatt cagagctagg aatgtggttt ataaaatagg aagtaattgt
2941 gtcaggtcac ttttatgcca cattatttta attgcaaaaa agcatctata tatggaggag
3001 ggtgggaaaa tagaggtagg aaatagtagc ctaaaggaaa tcgccacacg tctgtctaaa
3061 cttaggtctc ttttctccgt aggtacctcc ctgggtagtt ccacacacta ggttgtaaca
3121 gtctctccct gaggagcaga ctcccagcat ggtgtagcgt ggccctgtca tgcacatggg
3181 gtcccgcagc agtgactgtg tgtcctgcag aggcgtgacc caggcccctg tagccctcag
3241 cctcctctag aagcttctgt actccttgta ggatcagatc atggaaaact tttctcagtt
3301 tacttctaag taatcacaga taatacatgg ccagtaatcc caggctggcc attcattcag
3361 gttttttaaa ggatatttaa cttttatgga ctagaaggaa tcacgagggc tactgcacaa
3421 tacatggcct aagttccctc tgttccttcc tctgaatcga atggatgtgg gtgaccgccc
3481 gaaggccttc acaggatgga agtagaatga tttcagtaga tactcattct tggaaaatgc
3541 catagtttta aattattgtt tccagcttta tcaaagacat gtttgaaaaa taaaaagcat
3601 ccaagtgaga gctggtgaga ccacgtgctg ctggcgtagt gtaggccaga cattgacagt
3661 cctgacggga gctcagggct gcccagcgcc cagcgtgcac gggacggccc cacgacagag
3721 ggagtcagcc cgggaggtca ggagcgcggc gggcgagggc cctgtgtgga ccacctccac
3781 caagc
//