LOCUS HSU75686 3065 bp mRNA linear HUM 16-OCT-2018
DEFINITION Homo sapiens polyadenylate binding protein mRNA, complete cds.
ACCESSION U75686
VERSION U75686.2
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3065)
AUTHORS Houng,A.K., Maggini,L., Clement,C.Y. and Reed,G.L.
TITLE Identification and structure of activated-platelet protein-1, a
protein with RNA-binding domain motifs that is expressed by
activated platelets
JOURNAL Eur. J. Biochem. 243 (1-2), 209-218 (1997)
PUBMED 9030741
REFERENCE 2 (bases 1 to 3065)
AUTHORS Reed,G.L. and Houng,A.
TITLE Direct Submission
JOURNAL Submitted (21-OCT-1996) Cardiovascular Biology, Harvard, 665
Huntington Ave. II-127, Boston, MA 01890, USA
REFERENCE 3 (bases 1 to 3065)
AUTHORS Reed,G.L. and Houng,A.
TITLE Direct Submission
JOURNAL Submitted (16-OCT-2018) Cardiovascular Biology, Harvard, 665
Huntington Ave. II-127, Boston, MA 01890, USA
REMARK Sequence update by database staff to remove vector contamination
COMMENT On Oct 16, 2018 this sequence version replaced U75686.1.
FEATURES Location/Qualifiers
source 1..3065
/db_xref="H-InvDB:HIT000221269"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
5'UTR 1..794
CDS 795..2729
/note="APP-1"
/codon_start=1
/product="polyadenylate binding protein"
/protein_id="AAB97309.1"
/translation="MNAAASSYPMASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCR
DMITRRSLGYAYVNFQQPADAERALDTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVF
IKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNG
MLLNDRKVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTL
SVKVMRDPNGKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAEL
KRKFEQLKQERISRYQGVNLYIKNLDDTIDDEKLRKEFSPFGSITSAKVMLEDGRSKG
FGFVCFSSPEEATKAVTEMNGRIVGSKPLYVALAQRKEERKAHLTNQYMQRVAGMRAL
PANAILNQFQPAAGGYFVPAVPQAQGRPPYYTPNQLAQMRPNPRWQQGGRPQGFQGMP
SAIRQSGPRPTLRHLAPTGSECPDRLAMDFGGAGAAQQGLTDSCQSGGVPTAVQNLAP
RAAVAAAAPRAVAPYKYASSVRSPHPAIQPLQAPQPAVHVQGQEPLTASMLAAAPPQE
QKQMLGERLFPLIQTMHSNLAGKITGMLLEIDNSELLHMLESPESLRSKVDEAVAVLQ
AHHAKKEAAQKVGAVAAATS"
3'UTR 2730..3065
BASE COUNT 744 a 817 c 828 g 676 t
ORIGIN
1 gcagcctgag gaaaaaaaga gaaaaagata aaaaaaatct gaaaacgctt caaaatcctg
61 aaaaaaaaaa ggaaaagaaa aaacgaatcc tcggagaacc cgcggggaag tcactttcgt
121 acgcttccgg cctgccccgc gcccgccgcc gcagcgcttg gcgtccgtcg gtctccgtcc
181 gtcggtccgg gggtgagccg cccgcccggc ccgccgtgcc ctccccccgc tcgggccccg
241 agccccgcgc cccggcctgc cccggcgcac cacgtgtccg tgctgccctt cgccgcccgc
301 ccggggtcgc cgagtcggcg cccacaaaga tttggtttcc ctctgcccgg cggttgtaat
361 cttaaaccgc cggagcccga ggcctatatt tatagagaaa cgcgtgtccc cgaggcccgc
421 cgtgggcagc gtccggtcgc ctcttaaagg atttttaccc ttcggaaggg gattccccgt
481 ttaatttttt tcctactttg attttttgaa atttggagcc ttcgcaccag gaccgcggag
541 aagtgcaaag tcgcggggag ggccgtattg tgcggagagc cttttgtctg cggtgctgcg
601 gccgtgggag ccggcccccg cctcccgttt ccgtcccgtc tccaagcccg ccgactccag
661 ctcgtcctcg ccgcgccggt gccacctgtg agccggcgcg ggcccgggct ccggctccga
721 aggcgcccct ttgtcctgcg gcgggcccga taagaagtcc tctggcgggg ctcggggtgg
781 tggggggcgg ggagatgaac gctgcggcca gcagctaccc catggcctcc ctgtacgtgg
841 gcgacctgca ttcggacgtc accgaggcca tgctgtacga aaagttcagc cccgcggggc
901 ctgtgctgtc catccgggtc tgccgcgata tgatcacccg ccgctccctg ggctatgcct
961 acgtcaactt ccagcagccg gccgacgctg agcgggcttt ggacaccatg aactttgatg
1021 tgattaaggg aaagccaatc cgcatcatgt ggtctcagag ggatccctct ttgagaaaat
1081 ctggtgtggg aaacgtcttc atcaagaacc tggacaaatc tatagataac aaggcacttt
1141 atgatacttt ttctgctttt ggaaacatac tgtcctgcaa ggtggtgtgt gatgagaacg
1201 gctctaaggg ttatgccttt gtccacttcg agacccaaga ggctgccgac aaggccatcg
1261 agaagatgaa tggcatgctc ctcaatgacc gcaaagtatt tgtgggcaga ttcaagtctc
1321 gcaaagagcg ggaagctgag cttggagcca aagccaagga attcaccaat gtttatatca
1381 aaaactttgg ggaagaggtg gatgatgaga gtctgaaaga gctattcagt cagtttggta
1441 agaccctaag tgtcaaggtg atgagagatc ccaatgggaa atccaaaggc tttggctttg
1501 tgagttacga aaaacacgag gatgccaata aggctgtgga agagatgaat ggaaaagaaa
1561 taagtggtaa aatcatattt gtaggccgtg cacaaaagaa agtagaacgg caggcagagt
1621 taaaacggaa atttgaacag ttgaaacagg agagaattag tcgatatcag ggggtgaatc
1681 tctacattaa gaacttggat gacactattg atgatgagaa attaaggaaa gaattttctc
1741 cttttggatc aattaccagt gctaaggtaa tgctggagga tggaagaagc aaagggtttg
1801 gcttcgtctg cttctcatct cctgaagaag caaccaaagc agtcactgag atgaatggac
1861 gcattgtggg ctccaagcca ctatatgttg ccctggccca gaggaaggaa gagagaaagg
1921 ctcacctgac caaccagtat atgcaacgag tggctggaat gagagcactt cctgccaatg
1981 ccatcttaaa tcagttccag cctgcagcgg gtggctactt tgtgccagca gtcccacagg
2041 ctcagggaag gcctccatat tatacaccta accagttagc acagatgagg cctaatccac
2101 gctggcagca aggtgggaga cctcaaggct tccaaggaat gccaagtgct atacgccagt
2161 ctgggcctcg tccaactctt cgccatctgg ctccaactgg gtctgagtgc ccggaccgct
2221 tggctatgga ctttggtggg gctggtgccg cccagcaagg gctgactgac agctgccagt
2281 ctggaggcgt tcccacagct gtgcagaact tagcgccacg cgctgctgtt gctgctgctg
2341 ctccccgggc tgttgccccc tacaaatacg cctccagtgt ccgcagccct catcctgcca
2401 tacagcctct gcaggcaccc cagcctgcgg tccatgtgca ggggcaggag ccactgactg
2461 cctccatgct ggctgcagca cccccccagg aacagaagca gatgctggga gaacgcttgt
2521 tcccactcat ccaaacaatg cattcaaatc tggctgggaa gatcacggga atgctgctgg
2581 agatagacaa ctctgagctg ctgcacatgt tagagtcccc cgagtctctc cgctccaagg
2641 tggatgaagc tgtagcagtt ctacaggctc atcatgccaa gaaagaagct gcccagaagg
2701 tgggcgctgt tgctgctgct acctcttaga caaggaaaaa ccgattcaaa agccaaataa
2761 ccccttatgg aattcaactc aaggtttgaa gacttcctag cttgtcctat ggacctcaac
2821 accaaggatt acaaattgca aatttaatag gtcattttgt atcaaaaggt caattatgaa
2881 gcacctagaa tttttcaatt atacgaatat gttctttggg ttctgctgtg gcccagacag
2941 tgttaacttt ttttttattg tgggttttga ttttttcccc cagaaattgg ttttatttga
3001 tgtacccaag tcttacgttt cccaataaag aaaaaaaatc tccataaaaa aagtcgagcg
3061 gccgc
//